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Association of Thyroid Carcinoma with Gardner's Syndrome in Siblings
Abstract
WE are documenting the records of two sisters with Gardner's syndrome each of whom also had thyroid carcinoma. In view of the familial setting of their major illness, Gardner's syndrome, and its usual association with other tumors, the presence of thyroid carcinoma is probably meaningful.The most compelling aspect of Gardner's syndrome is familial polyposis of the large intestine, with a predisposition to colorectal cancer in early adulthood. Gardner and his colleagues described this condition with osteomas, fibromas and epidermal cysts and believed that the syndrome represents a disturbance in a single dominant gene.1 Newly reported cases, and the continuing . . .
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Cited by
HARACH, H. R., WILLIAMS, G. T., & WILLIAMS, E. D. (1994) · Histopathology · doi:10.1111/j.1365-2559.1994.tb01374.x · Cited by 259
Gastrointestinal manifestations of endocrine disease
Maser, C. (2006) · World Journal of Gastroenterology · doi:10.3748/wjg.v12.i20.3174 · Cited by 42
Adrenal carcinoma in a patient with Gardner's syndrome: imaging findings
Traill, Z., Tuson, J., & Woodham, C. (1995) · American Journal of Roentgenology · doi:10.2214/ajr.165.6.7484586 · Cited by 32
Metadata
- Authors
- Camiel, M. R., Mulé, J. E., Alexander, L. L., & Benninghoff, D. L.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1968-05-09
- Volume
- 278
- Issue
- 19
- Pages
- 1056-1058
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2089322236
- Cited by
- 224
- References
- 0
- FWCI
- 12.09
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Association of Thyroid Carcinoma with Gardner's Syndrome in Siblings. https://app.cochat.ai/papers/10.1056/nejm196805092781908
- The paper
- Camiel, M. R., Mulé, J. E., Alexander, L. L., & Benninghoff, D. L. (1968). Association of Thyroid Carcinoma with Gardner's Syndrome in Siblings. New England Journal of Medicine. https://doi.org/10.1056/nejm196805092781908
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
