The DOI matches its Crossref record.
Adverse Nondrug Reactions
Open accessAbstract
Healthy university students and hospital staff taking no medications were surveyed by questionnaire to obtain data on the occurrence of many symptoms often listed as side effects of drugs. Of 670 people surveyed, 414 indicated that they had had no illnesses and taken no medications during the previous three days and were included in the study. Only 19 per cent of the 414 stated that they had experienced none of 25 symptoms listed in the previous 72 hours. The median number of symptoms experienced per person was two. Thirty people experienced six or more of these symptoms. In the study of adverse drug reactions proper controls are just as important as in any other form of research.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Common symptoms in ambulatory care: incidence, evaluation, therapy, and outcome
Kroenke, K., & Mangelsdorff, A. D. (1989) · The American Journal of Medicine · doi:10.1016/0002-9343(89)90293-3 · Cited by 947
Nonspecific medication side effects and the nocebo phenomenon
Barsky, A. J. (2002) · JAMA · doi:10.1001/jama.287.5.622 · Cited by 784
Patients presenting with somatic complaints: epidemiology, psychiatric co‐morbidity and management
Kroenke, K. (2003) · International Journal of Methods in Psychiatric Research · doi:10.1002/mpr.140 · Cited by 624
The Prevalence of Symptoms in Medical Outpatients and the Adequacy of Therapy
Arrington, M. E. (1990) · Archives of Internal Medicine · doi:10.1001/archinte.1990.00040031685016 · Cited by 367
How many functional somatic syndromes?
Nimnuan, C., Rabe-Hesketh, S., Wessely, S., & Hotopf, M. (2001) · Journal of Psychosomatic Research · doi:10.1016/s0022-3999(01)00224-0 · Cited by 269
Metadata
- Authors
- Reidenberg, M. M., Lowenthal, D. T., & Sacks, R.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1968-09-26
- Volume
- 279
- Issue
- 13
- Pages
- 678-679
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2329307791
- Cited by
- 242
- References
- 0
- FWCI
- 9.07
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Adverse Nondrug Reactions. https://app.cochat.ai/papers/10.1056/nejm196809262791304
- The paper
- Reidenberg, M. M., Lowenthal, D. T., & Sacks, R. (1968). Adverse Nondrug Reactions. New England Journal of Medicine. https://doi.org/10.1056/nejm196809262791304
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
