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Surgically Confirmed Gallbladder Disease, Venous Thromboembolism, and Breast Tumors in Relation to Postmenopausal Estrogen Therapy
Abstract
The possible influence of estrogen-containing drugs (mainly conjugated estrogens) on gallbladder disease, venous thromboembolism and breast tumors in postmenopausal women 45 to 69 years of age was explored in a large hospital survey. As compared with controls, the estimate of relative risk for cases of surgically confirmed gallbladder disease occurring in otherwise healthy women was 2.5 (95 per cent confidence limits: 1.5 and 4.2), and the estimated incidence rate attributable to estrogens was 131 per 100,000 women at risk per year. Significant associations between estrogens and idiopathic venous thromboembolism, newly diagnosed breast cancer or benign breast tumors were not present. (N Engl J Med 290:15–19, 1974)
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Citations
Cited by
Hormone Therapy To Prevent Disease and Prolong Life in Postmenopausal Women
Grady, D., Rubin, S. M., Petitti, D. B., Fox, C. S., Black, D., Ettinger, B., Ernster, V. L., & Cummings, S. R. (1992) · Annals of Internal Medicine · doi:10.7326/0003-4819-117-12-1016 · Cited by 2,336
A Prospective Study of Postmenopausal Estrogen Therapy and Coronary Heart Disease
Stampfer, M. J., Willett, W. C., Colditz, G. A., Rosner, B., Speizer, F. E., & Hennekens, C. H. (1985) · New England Journal of Medicine · doi:10.1056/nejm198510243131703 · Cited by 850
Risk of venous thromboembolism in users of hormone replacement therapy
Daly, E., Vessey, M. P., Hawkins, M. M., Carson, J. L., Gough, P., & Marsh, S. (1996) · The Lancet · doi:10.1016/s0140-6736(96)07113-9 · Cited by 819
Hormonal Treatment of Postmenopausal Women
Wood, A. J. J., & Belchetz, P. E. (1994) · New England Journal of Medicine · doi:10.1056/nejm199404143301508 · Cited by 384
Hormone replacement therapy and risk of venous thromboembolism: population based case-control study
Gutthann, S. P., Rodriguez, L. A. G., Castellsague, J., & Oliart, A. D. (1997) · BMJ · doi:10.1136/bmj.314.7083.796 · Cited by 338
Metadata
- Authors
- the Boston Collaborative Drug Surveillance Program, B. U. M. C.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1974-01-03
- Volume
- 290
- Issue
- 1
- Pages
- 15-19
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W4232136535
- Cited by
- 345
- References
- 0
- FWCI
- 13.51
- Type
- journal article
- Language
- en
- Open access
- closed
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- the Boston Collaborative Drug Surveillance Program, B. U. M. C. (1974). Surgically Confirmed Gallbladder Disease, Venous Thromboembolism, and Breast Tumors in Relation to Postmenopausal Estrogen Therapy. New England Journal of Medicine. https://doi.org/10.1056/nejm197401032900104
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
