The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.
Neurotoxicity of Commonly Used Antineoplastic Agents
Abstract
Nitrogen Mustard (NSC-762)Nitrogen mustard (mechlorethamine) is the prototype of the "alkylating agent" class of Cytotoxic drugs. Favorable therapeutic effects from nitrogen mustard are common in Hodgkin's disease and other lymphomas and some solid tumors. The major toxicities of nitrogen mustard are bone-marrow suppression and gastrointestinal disturbances.There have been no reports of serious or life-threatening neurologic toxicity due to intravenous nitrogen mustard when conventional doses were used, except for a recent case presented by Bethlenfalvay and Bergin.85 They described a patient with Hodgkin's disease in whom chills, fever, hemiplegia, and coma developed within one week after each of two . . .
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Cites
Combination Chemotherapy in the Treatment of Advanced Hodgkin's Disease
DEVITA, V. T., SERPICK, A. A., & CARBONE, P. P. (1970) · Annals of Internal Medicine · doi:10.7326/0003-4819-73-6-881 · Cited by 1,436
Vincristine‐induced neuropathy: A clinical study of fifty leukemic patients
Sandier, S. G., Tobin, W., & Henderson, E. S. (1969) · Neurology · doi:10.1212/wnl.19.4.367 · Cited by 300
VINCRISTINE NEUROPATHY: CLINICAL AND ELECTROPHYSIOLOGICAL OBSERVATIONS
CASEY, E. B., JELLIFE, A. M., LE QUESNE, P. M., & MILLETT, Y. L. (1973) · Brain · doi:10.1093/brain/96.1.69 · Cited by 293
The neuromyopathy of vincristine in man
Bradley, W. G., Lassman, L. P., Pearce, G. W., & Walton, J. N. (1970) · Journal of the Neurological Sciences · doi:10.1016/0022-510x(70)90013-4 · Cited by 261
NEURONAL CHANGES INDUCED BY INTRATHECAL VINCRISTINE SULFATE
SCHOCHET, S. S., LAMPERT, P. W., & EARLE, K. M. (1968) · Journal of Neuropathology and Experimental Neurology · doi:10.1097/00005072-196810000-00008 · Cited by 205
The Physiology of Human Penile Erection
WEISS, H. D. (1972) · Annals of Internal Medicine · doi:10.7326/0003-4819-76-5-793 · Cited by 198
Self-citationShelanski, M. L. (1969) · Archives of Neurology · doi:10.1001/archneur.1969.00480080099012 · Cited by 136
Vincristine Neurotoxicity and Abnormal Secretion of Antidiuretic Hormone
Robertson, G. L. (1973) · Archives of Internal Medicine · doi:10.1001/archinte.1973.03650110061013 · Cited by 127
METHYL-HYDRAZINE IN TREATMENT OF HODGKIN'S DISEASE AND VARIOUS FORMS OF HÆMATOSARCOMA AND LEUKÆMIA
Mathé, G., Schweisguth, O., Schneider, M., Amiel, J. L., Bérumen, L., Brulé, G., Cattan, A. R., & Schwarzenberg, L. (1963) · The Lancet · doi:10.1016/s0140-6736(63)92854-x · Cited by 88
Suskind, R. M., Brusilow, S. W., & Zehr, J. E. (1972) · The Journal of Pediatrics · doi:10.1016/s0022-3476(72)80381-0 · Cited by 73
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Wefel, J. S., Kesler, S. R., Noll, K. R., & Schagen, S. B. (2015) · CA: A Cancer Journal for Clinicians · doi:10.3322/caac.21258 · Cited by 532
Chemotherapy-induced neuropathy: A comprehensive survey
Miltenburg, N. C., & Boogerd, W. (2014) · Cancer Treatment Reviews · doi:10.1016/j.ctrv.2014.04.004 · Cited by 431
The clinical pharmacology and use of antimicrotubule agents in cancer chemotherapeutics
Rowinsky, E. K., & Donehower, R. C. (1991) · Pharmacology & Therapeutics · doi:10.1016/0163-7258(91)90086-2 · Cited by 321
Vincristine hyperalgesia in the rat: A model of painful vincristine neuropathy in humans
Aley, K. O., Reichling, D. B., & Levine, J. D. (1996) · Neuroscience · doi:10.1016/0306-4522(96)00020-6 · Cited by 185
Lowenthal, R. M., & Eaton, K. (1996) · Hematology/Oncology Clinics of North America · doi:10.1016/s0889-8588(05)70378-6 · Cited by 104
Metadata
- Authors
- Weiss, H. D., Walker, M. D., & Wiernik, P. H.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1974-07-18
- Volume
- 291
- Issue
- 3
- Pages
- 127-133
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W3118885491
- Cited by
- 268
- References
- 10
- FWCI
- 4.49
- Type
- journal article
- Language
- en
- Open access
- closed
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- Weiss, H. D., Walker, M. D., & Wiernik, P. H. (1974). Neurotoxicity of Commonly Used Antineoplastic Agents. New England Journal of Medicine. https://doi.org/10.1056/nejm197407182910305
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
