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Cited by 246Renal Diseases and GlomerulopathiesAcute Kidney Injury ResearchVasculitis and related conditions

The DOI matches its Crossref record; 17 of the 17 references it cites were found in a registry or an index.

Antitubular Basement-Membrane Antibodies in Methicillin-Associated Interstitial Nephritis

Border, Wayne A., Lehman, David H., Egan, J. D., Sass, Hope J., Glode, John E., Wilson, Curtis B.·1974·New England Journal of Medicine

Abstract

Abstract Antitubular basement-membrane antibodies were detected by indirect immunofluorescence in the serum of a patient in whom severe renal failure developed while he was receiving methicillin. A renal biopsy showed a severe mononuclear interstitial infiltrate with focal areas of tubular degeneration. IgG, C3 and a methicillin antigen assumed to be dimethoxyphenylpenicilloyl were present in a linear pattern along the tubular basement membrane but not along the glomerular basement membrane. The dimethoxyphenylpenicilloyl-tubular-basement-membrane hapten protein conjugate apparently led to an immune response with antitubular basement-membrane antibodies being involved in the immunopathogenesis of the patient's interstitial nephritis. (N Engl J Med 291:381–384, 1974)

Overview

Integrity signals

Registry

Crossref · 10.1056/nejm197408222910803

Cites

17 of 17 references verified0 citation errors · 0 not checkable

Statistics

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Verification

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Citations

Cites

Show all 17 references

Research works printed but not linked: 4

  1. Gilbert, 1970, Ann Allergy, 28, 378
  2. Sugisaki, 1973, Lab Invest, 28, 658
  3. Weinstein L: Penicillin, The Pharmacological Basis of Therapeutics. Third edition. Edited by LS Goodman, A Gilman. New York, The Macmillan Company, 1965, pp 1193–1229
  4. Eisen HN: Antibody-antigen reactions, Microbiology. Second edition. Edited by BD Davis, R Dulbecco, HN Eisen, et al. Hagerstown, Maryland, Harper and Row, 1973, pp 359–404

Cited by

See all 246

Metadata

Authors
Border, W. A., Lehman, D. H., Egan, J. D., Sass, H. J., Glode, J. E., & Wilson, C. B.
Affiliations
Creighton University (US)
Venue
New England Journal of Medicine
Published
1974-08-22
Volume
291
Issue
8
Pages
381-384
ISSN
  • 0028-4793 (ISSN-L)
  • 1533-4406
OpenAlex
W2332571552
Cited by
246
References
17
Citations by year
2026: 3 · 2025: 3 · 2024: 2 · 2023: 1 · 2022: 4 · 2020: 1 · 2019: 2 · 2017: 3 · 2016: 2 · 2015: 5 · 2014: 2 · 2013: 2 · 2012: 1
FWCI
17.81
Type
journal article
Language
en
Open access
closed
Locations
  • New England Journal of Medicine (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Nephrology › Renal Diseases and Glomerulopathies
  • Health Sciences › Medicine › Nephrology › Acute Kidney Injury Research
  • Health Sciences › Medicine › Rheumatology › Vasculitis and related conditions
Keywords
drug-induced nephrotoxicity, methicillin, tubular basement membrane, immunopathogenesis, renal failure, tubular degeneration, C3 deposition
MeSH terms
Adult, Animals, Haplorhini, Antigens, Autoantibodies, Basement Membrane, Biopsy, Complement System Proteins, Drug Hypersensitivity, Fluorescent Antibody Technique, Haptens, Humans, Immunoglobulin G, Immune Sera, Kidney, Kidney Glomerulus, Kidney Tubules, Male, Methicillin, Nephritis, Interstitial, Protein Binding, Rabbits

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This page
CoChat. (2026). Citation check: Antitubular Basement-Membrane Antibodies in Methicillin-Associated Interstitial Nephritis. https://app.cochat.ai/papers/10.1056/nejm197408222910803
The paper
Border, W. A., Lehman, D. H., Egan, J. D., Sass, H. J., Glode, J. E., & Wilson, C. B. (1974). Antitubular Basement-Membrane Antibodies in Methicillin-Associated Interstitial Nephritis. New England Journal of Medicine. https://doi.org/10.1056/nejm197408222910803

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.