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Immunologic Mechanisms of Penicillin Allergy: A Haptenic Model System for the Study of Allergic Diseases of Man
Abstract
THE immunologic mechanisms of penicillin allergy are of interest to physicians, not only because of their practical value but also because they can serve as a model for the study of the immunologic mechanisms mediating human allergic diseases in general. Untoward reactions to drugs are not all allergic in mechanism, and the same clinical manifestation can have different fundamental causes. As examples, syncope after injection of penicillin may result from a vasovagal fear reaction or from true anaphylaxis, and hemolytic anemia may be due to a biochemical abnormality of the red blood cell (for example, that induced by primaquine) or . . .
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Cited by
Allergy Diagnostic Testing: An Updated Practice Parameter
Bernstein, I. L., Li, J. T., Bernstein, D. I., Hamilton, R., Spector, S. L., Tan, R., Sicherer, S., Golden, D. B. K., Khan, D. A., Nicklas, R. A., et al. (2008) · Annals of Allergy, Asthma & Immunology · doi:10.1016/s1081-1206(10)60305-5 · Cited by 723
A Controlled Trial of Immunotherapy in Insect Hypersensitivity
Hunt, K. J., Valentine, M. D., Sobotka, A. K., Benton, A. W., Amodio, F. J., & Lichtenstein, L. M. (1978) · New England Journal of Medicine · doi:10.1056/nejm197807272990401 · Cited by 710
Castells, M., Khan, D. A., & Phillips, E. J. (2019) · New England Journal of Medicine · doi:10.1056/nejmra1807761 · Cited by 270
Antitubular Basement-Membrane Antibodies in Methicillin-Associated Interstitial Nephritis
Border, W. A., Lehman, D. H., Egan, J. D., Sass, H. J., Glode, J. E., & Wilson, C. B. (1974) · New England Journal of Medicine · doi:10.1056/nejm197408222910803 · Cited by 246
THE PENICILLINS: A REVIEW AND UPDATE
Miller, E. L. (2002) · Journal of Midwifery & Women's Health · doi:10.1016/s1526-9523(02)00330-6 · Cited by 147
Metadata
- Authors
- Levine, B. B.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1966-11-17
- Volume
- 275
- Issue
- 20
- Pages
- 1115-1125
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W1975164622
- Cited by
- 262
- References
- 0
- FWCI
- 10.34
- Type
- journal article
- Language
- en
- Open access
- closed
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- Levine, B. B. (1966). Immunologic Mechanisms of Penicillin Allergy: A Haptenic Model System for the Study of Allergic Diseases of Man. New England Journal of Medicine. https://doi.org/10.1056/nejm196611172752009
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
