The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Treatment of Refractory Heart Failure with Infusion of Nitroprusside
Abstract
Abstract Sodium nitroprusside infused in 18 patients with intractable heart failure (nine with ischemic heart disease and nine with cardiomyopathy) produced a prompt reduction of left ventricular filling pressure (pulmonary wedge or left ventricular end-diastolic pressure) from an average of 32.2 to 17.2 mm Hg and a rise in cardiac output from an average of 2.98 to 5.2 liters per minute. Mean arterial pressure fell by 15 mm Hg, and heart rate was slightly but significantly slowed. Stroke volume and forward ejection fraction were nearly doubled. Responses were similar in ischemic heart disease and cardiomyopathy. A diuresis and natriuresis accompanied the infusion, and the clinical response was sustained in five patients in whom the drug was continued for 24 to 72 hours. These results suggest that intractable heart failure may be effectively treated by reduction in impedance to left ventricular ejection. (N Engl J Med 291:587–592, 1974)
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Cardiovascular effects of glucagon in man
Parmley, W. W., Glick, G., & Sonnenblick, E. H. (1968) · New England Journal of Medicine · doi:10.1056/nejm196807042790103 · Cited by 246
Cited by
Effect of Vasodilator Therapy on Mortality in Chronic Congestive Heart Failure
Cohn, J. N., Archibald, D. G., Ziesche, S., Franciosa, J. A., Harston, W. E., Tristani, F. E., Dunkman, W. B., Jacobs, W., Francis, G. S., Flohr, K. H., et al. (1986) · New England Journal of Medicine · doi:10.1056/nejm198606123142404 · Cited by 2,400
Self-citationDobutamine: A New Synthetic Cardioactive Sympathetic Amine
Koch-Weser, J., Sonnenblick, E. H., Frishman, W. H., & LeJemtel, T. H. (1979) · New England Journal of Medicine · doi:10.1056/nejm197901043000105 · Cited by 344
Franciosa, J. A., Blank, R. C., & Cohn, J. N. (1978) · The American Journal of Medicine · doi:10.1016/0002-9343(78)90047-5 · Cited by 104
Self-citationHo, D., Yan, L., Iwatsubo, K., Vatner, D. E., & Vatner, S. F. (2010) · Heart Failure Reviews · doi:10.1007/s10741-010-9183-5 · Cited by 68
Metadata
- Authors
- Guiha, N. H., Cohn, J. N., Mikulic, E., Franciosa, J. A., & Limas, C. J.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1974-09-19
- Volume
- 291
- Issue
- 12
- Pages
- 587-592
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2315615479
- Cited by
- 379
- References
- 1
- FWCI
- 19.15
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Treatment of Refractory Heart Failure with Infusion of Nitroprusside. https://app.cochat.ai/papers/10.1056/nejm197409192911201
- The paper
- Guiha, N. H., Cohn, J. N., Mikulic, E., Franciosa, J. A., & Limas, C. J. (1974). Treatment of Refractory Heart Failure with Infusion of Nitroprusside. New England Journal of Medicine. https://doi.org/10.1056/nejm197409192911201
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
