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Nonassociation of Adrenocorticosteroid Therapy and Peptic Ulcer
Abstract
IT is "known" that adrenocorticosteroid therapy is frequently complicated by the appearance or reactivation of peptic ulcers,1 and that these ulcers are often associated with bleeding and perforation.2 3 4 The basis for this knowledge is difficult to define. Although there are many anecdotal reports of the development of peptic ulcer in patients receiving adrenocorticosteroid (steroid) treatment that go back to the early days of cortisone therapy5 6 7 and several series of patients with a high incidence of ulcers,2 3 4 , 8 , 9 no definitive description of this relation can be found, and no objective confirmation of this association exists. A few reports that failed to find . . .
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Cited by
Meta-Analysis in Clinical Research
L'ABBÉ, K. A., DETSKY, A. S., & O'ROURKE, K. (1987) · Annals of Internal Medicine · doi:10.7326/0003-4819-107-2-224 · Cited by 1,267
Liu, D., Ahmet, A., Ward, L., Krishnamoorthy, P., Mandelcorn, E. D., Leigh, R., Brown, J. P., Cohen, A., & Kim, H. (2013) · Allergy, Asthma & Clinical Immunology · doi:10.1186/1710-1492-9-30 · Cited by 1,268
Corticosteroid Use and Peptic Ulcer Disease: Role of Nonsteroidal Anti-inflammatory Drugs
Piper, J. M., Ray, W. A., Daugherty, J. R., & Griffin, M. R. (1991) · Annals of Internal Medicine · doi:10.7326/0003-4819-114-9-735 · Cited by 608
Corticosteroids and risk of gastrointestinal bleeding: a systematic review and meta-analysis
Narum, S., Westergren, T., & Klemp, M. (2014) · BMJ Open · doi:10.1136/bmjopen-2013-004587 · Cited by 327
ALBERT, R. K., MARTIN, T. R., & LEWIS, S. W. (1980) · Annals of Internal Medicine · doi:10.7326/0003-4819-92-6-753 · Cited by 300
Metadata
- Authors
- Conn, H. O., & Blitzer, B. L.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1976-02-26
- Volume
- 294
- Issue
- 9
- Pages
- 473-479
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W1976754613
- Cited by
- 353
- References
- 0
- FWCI
- 20.41
- Type
- journal article
- Language
- en
- Open access
- closed
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- Conn, H. O., & Blitzer, B. L. (1976). Nonassociation of Adrenocorticosteroid Therapy and Peptic Ulcer. New England Journal of Medicine. https://doi.org/10.1056/nejm197602262940905
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
