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Cited by 381

The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.

Thyroid Cancer Occurring as a Late Consequence of Head-and-Neck Irradiation: Evaluation of 1056 Patients

Favus, Murray J., Schneider, Arthur B., Stachura, Max E., Arnold, John E., Ryo, U. Yun, Pinsky, Steven M., Colman, Martin, Arnold, Margaret J., Frohman, Lawrence A.·1976·New England Journal of Medicine
DOI 10.1056/nejm197605062941901
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Abstract

From January 1 to September 30, 1974, we examined 1056 of 5266 subjects (20.1%) who had received therapeutic irradiation primarily for infections and inflammatory disease of the upper respiratory tract at our institution during the 1940's and 1950's. The tonsillar and nasopharyngeal region was the treatment site in 85% of those examined. Palpable nodular thyroid disease was found in 16.5%, and nonpalpable lesions were detected by 99m Tc pertechnetate thyroid imaging in an additional 10.7%, for a prevalence of nodular disease of 27.2%. Operation on 71% with nodular disease revealed thyroid cancer in 33% (60 of 182). Preliminary analysis for potential risk factors suggests a correlation between radiation exposure and the presence of thyroid nodules (P less than 0.001). These findings indicate that nodular thyroid disease, both benign and malignant, continues as a major health problem for at least 35 years in exposed subjects.

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Metadata

Authors
Favus, M. J., Schneider, A. B., Stachura, M. E., Arnold, J. E., Ryo, U. Y., Pinsky, S. M., Colman, M., Arnold, M. J., & Frohman, L. A.
Venue
New England Journal of Medicine
Publisher
Massachusetts Medical Society
Published
1976-05-06
Volume
294
Issue
19
Pages
1019-1025
ISSN
  • 0028-4793 (ISSN-L)
  • 1533-4406
DOI
10.1056/nejm197605062941901
OpenAlex
W2034009689
Cited by
381
References
9
FWCI
24.12
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Thyroid Cancer Occurring as a Late Consequence of Head-and-Neck Irradiation: Evaluation of 1056 Patients. https://app.cochat.ai/papers/10.1056/nejm197605062941901
The paper
Favus, M. J., Schneider, A. B., Stachura, M. E., Arnold, J. E., Ryo, U. Y., Pinsky, S. M., Colman, M., Arnold, M. J., & Frohman, L. A. (1976). Thyroid Cancer Occurring as a Late Consequence of Head-and-Neck Irradiation: Evaluation of 1056 Patients. New England Journal of Medicine. https://doi.org/10.1056/nejm197605062941901

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.