Cited by 352Antibiotic Use and ResistanceAntibiotic Resistance in BacteriaPharmaceutical and Antibiotic Environmental Impacts

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Changes in Intestinal Flora of Farm Personnel after Introduction of a Tetracycline-Supplemented Feed on a Farm

Levy, Stuart B., FitzGerald, George B., Macone, Ann B.·1976·New England Journal of Medicine

DOI 10.1056/nejm197609092951103

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Abstract

A prospective study was undertaken to determine whether feeding farm animals antibiotics in feed caused changes in the intestinal bacterial flora of farm dwellers and their neighbors. Chickens were fed tetracycline-supplemented feed (tet-feed), and, as expected, within one week their intestinal flora contained almost entirely tetracycline-resistant organisms. Increased numbers of resistant intestinal bacteria also appeared, but more slowly, in farm members, but not their neighbors. Within five and six months, 31.3 per cent of weekly fecal samples from farm dwellers contained greater than 80 per cent tetracycline-resistant bacteria as compared to 6.8 per cent of the samples from the neighbors (P less than 0.001). Seven of the 11 farm members, but only three of the 24 neighbors, had two or more fecal samples containing greater than 80 per cent tetracycline-resistant coliforms (P less than 0.01). These resistant bacteria contained transferable plasmids conferring multiple antibiotic resistances. Selective pressure by tet-feed for antibiotic-resistant bacteria in chickens extends to human beings in contact with chickens and the feed.

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Antibiotic Susceptibility Testing by a Standardized Single Disk Method
Bauer, A. W., Kirby, W. M. M., Sherris, J. C., & Turck, M. (1966) · American Journal of Clinical Pathology · doi:10.1093/ajcp/45.4_ts.493 · Cited by 18,523
REPLICA PLATING AND INDIRECT SELECTION OF BACTERIAL MUTANTS
Lederberg, J., & Lederberg, E. M. (1952) · Journal of Bacteriology · doi:10.1128/jb.63.3.399-406.1952 · Cited by 1,355
INFECTIVE HEREDITY OF MULTIPLE DRUG RESISTANCE IN BACTERIA
Watanabe, T. (1963) · Bacteriological Reviews · doi:10.1128/br.27.1.87-115.1963 · Cited by 737
INFECTIVE HEREDITY OF MULTIPLE DRUG RESISTANCE IN BACTERIA
Watanabe, T. (1963) · Bacteriological Reviews · doi:10.1128/mmbr.27.1.87-115.1963 · Cited by 335
The Ecology of Transferable Drug Resistance in the Enterobacteria
Anderson, E. S. (1968) · Annual Review of Microbiology · doi:10.1146/annurev.mi.22.100168.001023 · Cited by 333
Spread of antibiotic-resistant plasmids from chicken to chicken and from chicken to man
Levy, S. B., FitzGerald, G. B., & Macone, A. B. (1976) · Nature · doi:10.1038/260040a0 · Cited by 325
Self-citation
Drug Resistance and its Transfer in Salmonella typhimurium
Anderson, E. S., & Lewis, M. J. (1965) · Nature · doi:10.1038/206579a0 · Cited by 202
R FACTORS IN ESCHERICHIA COLI IN FÆCES AFTER ORAL CHEMOTHERAPY IN GENERAL PRACTICE
Datta, N., Brumfitt, W., Faiers, M., Ørskov, F., Reeves, D. S., & Ørskov, I. (1971) · The Lancet · doi:10.1016/s0140-6736(71)91042-7 · Cited by 101
The effect of continuous administration of diets containing low levels of tetracyclines on the incidence of drug-resistant Bacterium coli in the faeces of pigs and chickens: the sensitivity of the Bact. coli to other chemotherapeutic agents.
Smith, H. W., & Crabb, W. E. (1957) · Veterinary Record · Cited by 88
Antibiotic resistance and transmissible R-factors in the intestinal coliform flora of healthy adults and children in an urban and a rural community
Linton, K. B., Lee, P. A., Richmond, M. H., Gillespie, W. A., Rowland, A. J., & Baker, V. N. (1972) · Journal of Hygiene · doi:10.1017/s0022172400022130 · Cited by 70

Show all 23 references

Research works printed but not linked: 3

1971, Ann NY Acad Sci, 182, 1
Richmond, 1974, Microbiology, 27
Smith, 1957, Vet Rec, 69, 24

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Deckers, J. (2016) · Ubiquity Press eBooks · doi:10.5334/bay · Cited by 60
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Brown, M. B., & Roberts, M. C. (1991) · Veterinary Microbiology · doi:10.1016/0378-1135(91)90124-x · Cited by 28
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Scioli, C., Esposito, S., ANZILOTTI, G., Pavone, A., & Pennucci, C. (1983) · Poultry Science · doi:10.3382/ps.0620382 · Cited by 27
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Self-citation
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Escherichia coli mastitis.
Hill, A. W., & Gyles, C. L. (1994) · Cited by 23
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Pillai, S. D., Widmer, K. W., Maciorowski, K. G., & Ricke, S. C. (1997) · Journal of Environmental Science and Health Part A Environmental Science and Engineering and Toxicology · doi:10.1080/10934529709376635 · Cited by 22
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Authors: Levy, S. B., FitzGerald, G. B., & Macone, A. B.
Affiliations: Tufts University (US)
ORCID: Levy, Stuart B.
Venue: New England Journal of Medicine
Publisher: Massachusetts Medical Society
Published: 1976-09-09
Volume: 295
Issue: 11
Pages: 583-588
ISSN: 0028-4793 (ISSN-L)
1533-4406
DOI: 10.1056/nejm197609092951103
OpenAlex: W2325966728
Cited by: 352
References: 23
Citations by year: 2025: 7 · 2024: 8 · 2023: 6 · 2022: 5 · 2021: 10 · 2020: 14 · 2019: 8 · 2018: 10 · 2017: 15 · 2016: 19 · 2015: 15 · 2014: 18 · 2013: 14 · 2012: 8
FWCI: 26.97
Type: journal article
Language: en
Open access: closed
Locations: New England Journal of Medicine (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Infectious Diseases › Antibiotic Use and Resistance
Health Sciences › Medicine › Microbiology (medical) › Antibiotic Resistance in Bacteria
Physical Sciences › Environmental Science › Pollution › Pharmaceutical and Antibiotic Environmental Impacts
Keywords: tetracycline resistance, antibiotic resistance, intestinal bacterial flora, farm workers, poultry feed, chickens, coliform bacteria, plasmid-mediated resistance, selection pressure
MeSH terms: Adolescent, Adult, Agriculture, Animals, Animal Feed, Animals, Domestic, Bacteria, Chickens, Child, Child, Preschool, Drug Resistance, Microbial, Eggs, Feces, Female, Food Microbiology, Humans, Intestines, Male, Occupations, R Factors, Tetracyclines

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Changes in Intestinal Flora of Farm Personnel after Introduction of a Tetracycline-Supplemented Feed on a Farm

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