The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Hypothalamic Dysfunction in Secondary Amenorrhea Associated with Simple Weight Loss
Abstract
We tested hypothalamic, pituitary and endocrine function in 19 patients with secondary amenorrhea associated with simple weight loss who did not have anorexia nervosa to evaluate the effects of weight loss on these systems. Thermoregulation at 10 degrees C and 49 degrees C was abnormal and correlated with the percentage below ideal body weight (r = 0.62, P less than 0.02, and r = 0.55, P less than 0.05, respectively). Partial diabetes insipidus was found in 27 per cent of patients with simple weight loss. They had delayed peak plasma luteinizing hormone levels after 10 microgram of luteinizing-hormone-releasing factor, which was correlated with percentage below ideal body weight (r = 0.49, P less than 0.05). Delayed peak plasma thyrotropin levels after 500 microgram of thyrotropin-releasing factor were found. No prolactin, pituitary, thyroid or adrenal abnormalities were present. These findings are qualitatively similar to results of studies in 29 patients with anorexia nervosa, but less severe and less frequently present. We conclude that hypothalamic dysfunction may be caused by weight loss per se.
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Frisch, R. E., & McArthur, J. W. (1974) · Science · doi:10.1126/science.185.4155.949 · Cited by 1,412
Characterization of the normal temporal pattern of plasma corticosteroid levels.
KRIEGER, D. T., ALLEN, W., RIZZO, F., & KRIEGER, H. P. (1971) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-32-2-266 · Cited by 549
Cortisol Secretion and Metabolism in Anorexia Nervosa
Boyar, R. M., Hellman, L. D., Roffwarg, H., Katz, J., Zumoff, B., O'Connor, J., Bradlow, H. L., & Fukushima, D. K. (1977) · New England Journal of Medicine · doi:10.1056/nejm197701272960403 · Cited by 285
Cited by
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Skole, D., & Tucker, C. (1993) · Science · doi:10.1126/science.260.5116.1905 · Cited by 1,590
Metabolic fuels and reproduction in female mammals
Wade, G. N., & Schneider, J. E. (1992) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(05)80183-6 · Cited by 686
ACSM Position Stand: The Female Athlete Triad
Otis, C. L., Drinkwater, B., Johnson, M., Loucks, A., & Wilmore, J. (1997) · Medicine & Science in Sports & Exercise · doi:10.1097/00005768-199705000-00037 · Cited by 515
Comparative and evolutionary dimensions of the energetics of human pregnancy and lactation.
Dufour, D. L., & Sauther, M. L. (2002) · American Journal of Human Biology · doi:10.1002/ajhb.10071 · Cited by 326
Endocrine markers of semistarvation in healthy lean men in a multistressor environment
Friedl, K. E., Moore, R. J., Hoyt, R. W., Marchitelli, L. J., Martinez-Lopez, L. E., & Askew, E. W. (2000) · Journal of Applied Physiology · doi:10.1152/jappl.2000.88.5.1820 · Cited by 316
Metadata
- Authors
- Vigersky, R. A., Andersen, A. E., Thompson, R. H., & Loriaux, D. L.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1977-11-24
- Volume
- 297
- Issue
- 21
- Pages
- 1141-1145
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2001974806
- Cited by
- 311
- References
- 3
- FWCI
- 10.74
- Type
- journal article
- Language
- en
- Open access
- closed
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