The DOI matches its Crossref record.
Aerosolized Ribavirin Treatment of Infants with Respiratory Syncytial Viral Infection: A Randomized Double-Blind Study
Abstract
We evaluated a new antiviral agent, ribavirin, in the treatment of infants hospitalized with lower-respiratory-tract disease from respiratory syncytial virus. Ribavirin or placebo was administered to 33 infants in a double-blind manner by continuous aerosol for three to six days. Seventeen infants were treated with placebo, and 16 with ribavirin. By the end of treatment, infants receiving ribavirin had significantly greater improvement in their overall score for severity of illness, in lower-respiratory-tract signs, and in arterial oxygen saturation. Viral shedding was also diminished in the treated groups as compared with the placebo group. No side effects or toxicity were associated with the aerosol therapy. Isolates of respiratory syncytial virus obtained from the infants over the course of therapy showed no change in sensitivity to ribavirin.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Acute respiratory illness in the community: frequency of illness and the agents involved
Monto, A. S., & Sullivan, K. M. (1993) · Epidemiology and Infection · doi:10.1017/s0950268800050779 · Cited by 458
Wu, H., Pfarr, D. S., Johnson, S., Brewah, Y. A., Woods, R. M., Patel, N. K., White, W. I., Young, J. F., & Kiener, P. A. (2007) · Journal of Molecular Biology · doi:10.1016/j.jmb.2007.02.024 · Cited by 373
Kim, H. W., Wyatt, R. G., Fernie, B. F., Brandt, C. D., Arrobio, J. O., Jeffries, B. C., & Parrott, R. H. (1983) · Journal of Clinical Microbiology · doi:10.1128/jcm.18.6.1399-1404.1983 · Cited by 66
Chimote, G., & Banerjee, R. (2009) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.31959 · Cited by 41
Metadata
- Authors
- Hall, C. B., McBride, J. T., Walsh, E. E., Bell, D. M., Gala, C. L., Hildreth, S., Ten Eyck, L. G., & Hall, W. J.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1983-06-16
- Volume
- 308
- Issue
- 24
- Pages
- 1443-1447
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2319815586
- Cited by
- 550
- References
- 0
- FWCI
- 31.83
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Aerosolized Ribavirin Treatment of Infants with Respiratory Syncytial Viral Infection: A Randomized Double-Blind Study. https://app.cochat.ai/papers/10.1056/nejm198306163082403
- The paper
- Hall, C. B., McBride, J. T., Walsh, E. E., Bell, D. M., Gala, C. L., Hildreth, S., Ten Eyck, L. G., & Hall, W. J. (1983). Aerosolized Ribavirin Treatment of Infants with Respiratory Syncytial Viral Infection: A Randomized Double-Blind Study. New England Journal of Medicine. https://doi.org/10.1056/nejm198306163082403
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
