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Cited by 1,077

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

The Primary Immunodeficiencies

Rosen, Fred S., Cooper, Max D., Wedgwood, Ralph J. P.·1984·New England Journal of Medicine

Abstract

Selective Deficiency of Other Immunoglobulin IsotypesAs techniques have become available, isolated deficiencies of each immunoglobulin isotype or subclass have been described. Perhaps the best known is IgM deficiency, which has been associated with meningococcemia and other severe or recurrent infections.74,75 The decrease in serum IgM levels may not be primary in all instances. Patients with gluten enteropathy, for example, may have a marked isolated IgM deficiency that resolves on treatment with a gluten-free diet.76 From the viewpoint of immunobiology, the selective absence of IgM is difficult to explain, since IgM synthesis and secretion precede production of IgG and IgA. . . .

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Metadata

Authors
Rosen, F. S., Cooper, M. D., & Wedgwood, R. J. P.
Venue
New England Journal of Medicine
Published
1984-08-02
Volume
311
Issue
5
Pages
300-310
ISSN
  • 0028-4793 (ISSN-L)
  • 1533-4406
OpenAlex
W2035800046
Cited by
1,077
References
2
FWCI
9.27
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: The Primary Immunodeficiencies. https://app.cochat.ai/papers/10.1056/nejm198408023110506
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Rosen, F. S., Cooper, M. D., & Wedgwood, R. J. P. (1984). The Primary Immunodeficiencies. New England Journal of Medicine. https://doi.org/10.1056/nejm198408023110506

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.