Clinical Practice Guideline (Update): Adult Sinusitis
Open accessAbstract
Objective: This update of a 2007 guideline from the American Academy of Otolaryngology—Head and Neck Surgery Foundation provides evidence‐based recommendations to manage adult rhinosinusitis, defined as symptomatic inflammation of the paranasal sinuses and nasal cavity. Changes from the prior guideline include a consumer added to the update group, evidence from 42 new systematic reviews, enhanced information on patient education and counseling, a new algorithm to clarify action statement relationships, expanded opportunities for watchful waiting (without antibiotic therapy) as initial therapy of acute bacterial rhinosinusitis (ABRS), and 3 new recommendations for managing chronic rhinosinusitis (CRS). Purpose: The purpose of this multidisciplinary guideline is to identify quality improvement opportunities in managing adult rhinosinusitis and to create explicit and actionable recommendations to implement these opportunities in clinical practice. Specifically, the goals are to improve diagnostic accuracy for adult rhinosinusitis, promote appropriate use of ancillary tests to confirm diagnosis and guide management, and promote judicious use of systemic and topical therapy, which includes radiography, nasal endoscopy, computed tomography, and testing for allergy and immune function. Emphasis was also placed on identifying multiple chronic conditions that would modify management of rhinosinusitis, including asthma, cystic fibrosis, immunocompromised state, and ciliary dyskinesia. Action statements: The update group made strong recommendations that clinicians (1) should distinguish presumed ABRS from acute rhinosinusitis (ARS) caused by viral upper respiratory infections and noninfectious conditions and (2) should confirm a clinical diagnosis of CRS with objective documentation of sinonasal inflammation, which may be accomplished using anterior rhinoscopy, nasal endoscopy, or computed tomography. The update group made recommendations that clinicians (1) should either offer watchful waiting (without antibiotics) or prescribe initial antibiotic therapy for adults with uncomplicated ABRS; (2) should prescribe amoxicillin with or without clavulanate as first‐line therapy for 5 to 10 days (if a decision is made to treat ABRS with an antibiotic); (3) should reassess the patient to confirm ABRS, exclude other causes of illness, and detect complications if the patient worsens or fails to improve with the initial management option by 7 days after diagnosis or worsens during the initial management; (4) should distinguish CRS and recurrent ARS from isolated episodes of ABRS and other causes of sinonasal symptoms; (5) should assess the patient with CRS or recurrent ARS for multiple chronic conditions that would modify management, such as asthma, cystic fibrosis, immunocompromised state, and ciliary dyskinesia; (6) should confirm the presence or absence of nasal polyps in a patient with CRS; and (7) should recommend saline nasal irrigation, topical intranasal corticosteroids, or both for symptom relief of CRS. The update group stated as options that clinicians may (1) recommend analgesics, topical intranasal steroids, and/or nasal saline irrigation for symptomatic relief of viral rhinosinusitis; (2) recommend analgesics, topical intranasal steroids, and/or nasal saline irrigation) for symptomatic relief of ABRS; and (3) obtain testing for allergy and immune function in evaluating a patient with CRS or recurrent ARS. The update group made recommendations that clinicians (1) should not obtain radiographic imaging for patients who meet diagnostic criteria for ARS, unless a complication or alternative diagnosis is suspected, and (2) should not prescribe topical or systemic antifungal therapy for patients with CRS.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
ARS is defined as sudden onset of sinonasal symptoms with sinonasal inflammation lasting less than 4 weeks.
“ARS is defined as the sudden onset of sinonasal symptoms with associated sinonasal inflammation that lasts less than 4 weeks.1,137,138,266,267”
From International Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (2018) · cites this paper as [137]
The Introduction (p. 2) classifies ARS as lasting less than 4 weeks, supporting the duration. The guideline’s definition (p. 9) specifies purulent nasal drainage accompanied by nasal obstruction or facial pain-pressure-fullness; it does not define ARS by sudden onset or by associated sinonasal inflammation alone. (LLM, conf=0.85)
Experimental — accuracy not yet measuredFever is not included in other ARS guidelines due to its low specificity and sensitivity.
“Fever is not included in other guidelines, due to its low specificity and sensitivity.137”
From International Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (2018) · cites this paper as [137]
In “Transition from Viral to Bacterial Infection” (p. 10), the guideline says fever has about 50% sensitivity and specificity for ABRS and explains that it therefore did not include fever as a cardinal diagnostic sign. The same section says other guidelines do use high fever in criteria for severe presentations, so this source does not support the broader claim that fever is omitted from other guidelines generally. (LLM, conf=0.88)
Experimental — accuracy not yet measuredRARS is defined as at least 4 episodes of ARS per year, with disease-free intervals between episodes.
“RARS is defined as at least 4 episodes of ARS per year, with disease-free intervals between episodes.1,137,138,266,268”
From International Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (2018) · cites this paper as [137]
The Introduction (p. 2) describes recurrent ARS as four or more annual episodes of rhinosinusitis without persistent symptoms between them. The Recurrent Acute Rhinosinusitis section (p. 21) specifies a narrower diagnostic requirement: each episode must meet the criteria for acute bacterial rhinosinusitis (ABRS), not merely ARS. (LLM, conf=0.84)
Experimental — accuracy not yet measuredDevelopment of acute, moderate to severe symptoms and nasal purulence may be consistent with ARS or RARS rather than AR.
“The development of acute, moderate to severe symptoms, and nasal purulence may be consistent with ARS or RARS rather than AR.1,137,138”
From International Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (2018) · cites this paper as [137]
The guideline defines ARS by acute purulent nasal drainage accompanied by nasal obstruction or facial pain-pressure-fullness (Cardinal Symptoms of Acute Rhinosinusitis, p. 6). It defines RARS by four or more qualifying bacterial episodes per year (Recurrent Acute Rhinosinusitis, p. 21), so one episode of acute symptoms does not establish RARS. The cited passages do not establish moderate-to-severe symptoms as a distinguishing feature or directly compare this presentation with allergic rhinitis. (LLM, conf=0.84)
Experimental — accuracy not yet measuredModerate to severe facial pain and/or fever are atypical for isolated AR and may indicate ARS or acute exacerbation of CRS, differentiated by duration and chronicity.
“Moderate to severe facial pain and/or fever would also be atypical for isolated AR and may indicate the presence of an episode of ARS or an acute exacerbation of CRS, differentiated by duration and chronicity of symptoms.1,137,138”
From International Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (2018) · cites this paper as [137]
The Introduction (p. 2) distinguishes ARS from CRS by duration and notes that CRS can have acute exacerbations; the CRS section (p. 20) lists fever and describes episodic infections. The Cardinal Symptoms section (p. 6) includes facial pain in ARS, but requires accompanying purulent nasal drainage. The guideline does not state that moderate-to-severe facial pain or fever is atypical of isolated allergic rhinitis, so that part is not supported by this source. (LLM, conf=0.84)
Experimental — accuracy not yet measured
Progressive worsening over a short period (5 days) suggests bacterial ARS.
“Progressive worsening over a short period of time (ie, 5 days) is also suggestive of bacterial ARS.137,138”
From International Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (2018) · cites this paper as [137]
The guideline’s “Transition from Viral to Bacterial Infection” section (p. 9) says that, between days 5 and 10, initial improvement followed by worsening (“double worsening”) is consistent with bacterial ARS. It does not say that progressive worsening over 5 days, without initial improvement, is suggestive of bacterial ARS. (LLM, conf=0.86)
Experimental — accuracy not yet measuredARS symptoms typically last days to weeks but no more than 4 weeks, while CRS symptoms persist daily for greater than 12 weeks.
“The timing of symptoms may also help delineate between rhinosinusitis and AR as ARS symptoms typically last days to weeks (but no more than 4 weeks), CRS symptoms persist daily for greater than 12 weeks.”
From International Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (2018) · cites this paper as [137]
The Introduction (p. 2) defines ARS as lasting up to 4 weeks and CRS as lasting more than 12 weeks; the CRS section (p. 20) also describes symptoms persisting beyond 12 weeks. The guideline does not specify that CRS symptoms must occur daily, so that added qualifier is not supported. (LLM, conf=0.84)
Experimental — accuracy not yet measuredARS symptoms include nasal congestion, nasal obstruction or nasal discharge, and facial pressure or pain, or anosmia or hyposmia.
“Symptoms include nasal congestion, nasal obstruction or nasal discharge, and facial pressure or pain, or anosmia/hyposmia.”
From International Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (2018) · cites this paper as [137]
The Cardinal Symptoms section (p. 6) supports nasal obstruction and facial pain or pressure, while the Definition (p. 9) treats congestion as another description of obstruction and lists anosmia and hyposmia as additional symptoms of acute bacterial rhinosinusitis. The claim omits an important qualification: the guideline defines acute rhinosinusitis by purulent, not just any, nasal drainage accompanied by obstruction or facial pain or pressure. (LLM, conf=0.86)
Experimental — accuracy not yet measuredFacial pressure and pain in ARS is described as moderate to severe.
“Facial pressure and pain is described as moderate to severe.137”
From International Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (2018) · cites this paper as [137]
The Cardinal Symptoms of Acute Rhinosinusitis section (p. 6) identifies facial pain-pressure-fullness as a symptom of ARS. The Choice of Initial Antibiotic section (p. 17) mentions moderate-to-severe ABRS symptoms, but does not describe facial pressure or pain specifically as moderate to severe. (LLM, conf=0.88)
Experimental — accuracy not yet measuredA longer duration of illness suggests bacterial ARS.
“A longer duration of illness suggests bacterial ARS.137,138”
From International Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (2018) · cites this paper as [137]
CRS is divided into 2 main phenotypic groups: CRSwNP and CRSsNP.
“CRS is divided into 2 main phenotypic groups: CRSwNP and CRSsNP.”
From International Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (2018) · cites this paper as [137]
CRS is an inflammatory condition of the sinonasal cavity persisting for more than 12 weeks with at least 2 symptoms of nasal obstruction and congestion, mucopurulent nasal drainage, facial pressure or pain, and anosmia or hyposmia.
“CRS is an inflammatory condition of the sinonasal cavity persisting for more than 12 weeks with at least 2 symptoms of nasal obstruction and congestion, mucopurulent nasal drainage (anterior or posterior), facial pressure or pain, and anosmia/hyposmia.1,137,138,266,267”
From International Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (2018) · cites this paper as [137]
CRS patients must have objective evidence of sinonasal inflammation on nasal endoscopy (polyps, edema, mucopurulent rhinorrhea) or CT scans of the sinuses.
“In addition, patients must have objective evidence of sinonasal inflammation on either nasal endoscopy (polyps, edema, mucopurulent rhinorrhea) or on CT scans of the sinuses.137,138,266,267”
From International Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (2018) · cites this paper as [137]
Viral ARS is generally present for less than 10 days.
“In general, viral ARS is present for less than 10 days.”
From International Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (2018) · cites this paper as [137]
Prolonged duration of symptoms greater than 12 weeks should raise suspicions for CRS and prompt further investigation.
“A prolonged duration of symptoms (greater than 12 weeks) should raise suspicions for CRS and prompt further investigation.1,137,138”
From International Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (2018) · cites this paper as [137]
AR symptoms are variable in duration and tend to have seasonal or exposure-related fluctuations.
“In comparison, while AR symptoms are variable in duration, they tend to have seasonal or exposure-related fluctuations.1,137,138”
From International Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (2018) · cites this paper as [137]
The Introduction (p. 2) describes the duration of rhinosinusitis, not allergic rhinitis. Testing for Allergy (p. 26) discusses allergic rhinitis in relation to sinusitis but does not describe its symptom duration or seasonal or exposure-related fluctuations. Searches for those patterns found no passage addressing the claim. (LLM, conf=0.72)
Experimental — accuracy not yet measuredAR is typically not associated with purulent or unilateral nasal discharge.
“Conversely, AR is typically not associated with purulent or unilateral nasal discharge.”
From International Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (2018) · cites this paper as [137]
The Definition (p. 9) describes purulent discharge in acute rhinosinusitis, while Testing for Allergy (p. 26) discusses allergic rhinitis’s association with sinusitis. Neither passage characterizes discharge in allergic rhinitis as typically nonpurulent or nonunilateral. Searches for allergic-rhinitis symptoms and unilateral discharge found no passage addressing that claim. (LLM, conf=0.72)
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
8 retracted
Nasal saline irrigations for the symptoms of chronic rhinosinusitis
Harvey, R. J., Hannan, S. A., Badia, L., & Scadding, G. K. (2007) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd006394.pub2 · Cited by 298 · see citing works
RetractedNasal saline irrigations for the symptoms of chronic rhinosinusitis
Harvey, R. J., Hannan, S. A., Badia, L., & Scadding, G. K. (2007) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd006394 · Cited by 194 · see citing works
RetractedTopical steroids for nasal polyps
Kalish, L. H., Snidvongs, K., Sivasubramaniam, R., Cope, D. H., & Harvey, R. J. (2012) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd006549.pub2 · Cited by 132 · see citing works
RetractedTopical steroid for chronic rhinosinusitis without polyps
Snidvongs, K., Kalish, L. H., Sacks, R., Craig, J. C., & Harvey, R. J. (2011) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd009274 · Cited by 112 · see citing works
RetractedAntibiotics for acute maxillary sinusitis in adults
Ahovuo-Saloranta, A., Rautakorpi, U.-M., Borisenko, O., Liira, H., Williams, J. W., & Mākelä, M. (2014) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd000243.pub3 · Cited by 83 · see citing works
RetractedTopical and systemic antifungal therapy for the symptomatic treatment of chronic rhinosinusitis
Sacks, P., Harvey, R. J., Rimmer, J., Gallagher, R. M., & Sacks, R. (2011) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd008263.pub2 · Cited by 69 · see citing works
RetractedAntibiotics for acute maxillary sinusitis in adults
Ahovuo-Saloranta, A., Rautakorpi, U.-M., Borisenko, O., Liira, H., Williams, J. W., & Mākelä, M. (2015) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd000243.pub4 · Cited by 26 · see citing works
RetractedTopical steroid for chronic rhinosinusitis without polyps
Snidvongs, K., Kalish, L. H., Sacks, R., Craig, J. C., & Harvey, R. J. (2016) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd009274.pub2 · Cited by 20 · see citing works
RetractedEuropean Position Paper on Rhinosinusitis and Nasal Polyps 2020
Fokkens, W. J., Lund, V. J., Hopkins, C., Hellings, P. W., Kern, R., Reitsma, S., Toppila-Salmi, S., Bernal-Sprekelsen, M., Mullol, J., Alobid, I., et al. (2020) · Rhinology journal · doi:10.4193/rhin20.600 · Cited by 5,882 · see citing works
Self-citationOutpatient antibiotic use in Europe and association with resistance: a cross-national database study
Goossens, H., Ferech, M., Vander Stichele, R., & Elseviers, M. (2005) · The Lancet · doi:10.1016/s0140-6736(05)17907-0 · Cited by 3,359 · see citing works
Clinical Practice Guidelines We Can Trust
Board on Health Care Services (2011) · National Academies Press eBooks · doi:10.17226/13058 · Cited by 3,102 · see citing works
Craig, W. A. (1998) · Clinical Infectious Diseases · doi:10.1086/516284 · Cited by 2,908 · see citing works
Fokkens, W. J., Lund, V. J., Mullol, J., Bachert, C., Alobid, I., Baroody, F., Cohen, N., Cervin, A., Douglas, R., Gevaert, P., et al. (2012) · Rhinology journal · doi:10.4193/rhino12.000 · Cited by 2,387 · see citing works
Summary health statistics for U.S. adults: national health interview survey, 2012.
Blackwell, D. L., Lucas, J. W., & Clarke, T. C. (2014) · PubMed · Cited by 1,889 · see citing works
Current estimates from the National Health Interview Survey.
Ss, J. (1981) · PubMed · Cited by 1,866 · see citing works
Summary Health Statistics for U.S. Adults: National Health Interview Survey, 2006
Pleis, J. R., & Lethbridge‐Çejku, M. (2007) · PsycEXTRA Dataset · doi:10.1037/e403882008-001 · Cited by 1,432 · see citing works
Current estimates from the National Health Interview Survey, 1990.
Adams, P. F., Hendershot, G. E., & Marano, M. A. (1987) · PubMed · Cited by 1,104 · see citing works
Pharmacodynamics of intravenous ciprofloxacin in seriously ill patients
Forrest, A., Nix, D. E., Ballow, C. H., Goss, T. F., Birmingham, M. C., & Schentag, J. J. (1993) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.37.5.1073 · Cited by 1,101 · see citing works
The Primary Immunodeficiencies
Rosen, F. S., Cooper, M. D., & WEDGWOOD, R. J. P. (1984) · New England Journal of Medicine · doi:10.1056/nejm198408023110506 · Cited by 1,097 · see citing works
Bolger, W. E., Parsons, D. S., & Butzin, C. A. (1991) · The Laryngoscope · doi:10.1288/00005537-199101000-00010 · Cited by 1,018 · see citing works
Adult Chronic Rhinosinusitis: Definitions, Diagnosis, Epidemiology, and Pathophysiology
Benninger, M. S., Ferguson, B. J., Hadley, J. A., Hamilos, D. L., Jacobs, M. R., Kennedy, D. W., Lanza, D. C., Marple, B. F., Osguthorpe, J. D., Stankiewicz, J. A., et al. (2003) · Otolaryngology · doi:10.1016/s0194-5998(03)01397-4 · Cited by 942 · see citing works
The Diagnosis and Incidence of Allergic Fungal Sinusitis
Ponikau, J. U., Sherris, D. A., Kern, E. B., Homburger, H. A., Frigas, E., Gaffey, T. A., & Roberts, G. D. (1999) · Mayo Clinic Proceedings · doi:10.4065/74.9.877 · Cited by 918 · see citing works
Clinical practice guideline: Adult sinusitis
Rosenfeld, R. M., Andes, D. R., Bhattacharyya, N., Cheung, D., Eisenberg, S., Ganiats, T. G., Gelzer, A. D., Hamilos, D. L., Haydon, R. C., Hudgins, P. A., et al. (2007) · Otolaryngology · doi:10.1016/j.otohns.2007.06.726 · Cited by 909 · see citing works
Self-citationLanza, D. C., & Kennedy, D. W. (1997) · Otolaryngology · doi:10.1016/s0194-5998(97)70001-9 · Cited by 757 · see citing works
The Relationship between Antimicrobial Use and Antimicrobial Resistance in Europe
Bronzwaer, S. L. A. M., Cars, O., Buchholz, U., Mölstad, S., Goettsch, W., Veldhuijzen, I. K., Kool, J. L., Sprenger, M. J. W., Degener, J. E., & System, P. I. T. E. A. R. S. (2002) · Emerging infectious diseases · doi:10.3201/eid0803.010192 · Cited by 691 · see citing works
The health impact of chronic sinusitis in patients seeking otolaryngologic care
Gliklich, R. E., & Metson, R. B. (1995) · Otolaryngology · doi:10.1016/s0194-5998(95)70152-4 · Cited by 687 · see citing works
Computed tomographic study of the common cold
Gwaltney, J. M., Phillips, C. D., Miller, R. D., & Riker, D. K. (1994) · New England Journal of Medicine · doi:10.1056/nejm199401063300105 · Cited by 668 · see citing works
Relationships Between Authors of Clinical Practice Guidelines and the Pharmaceutical Industry
Choudhry, N. K. (2002) · JAMA · doi:10.1001/jama.287.5.612 · Cited by 645 · see citing works
IDSA Clinical Practice Guideline for Acute Bacterial Rhinosinusitis in Children and Adults
Chow, A. W., Benninger, M. S., Brook, I., Brożek, J., Goldstein, E. J. C., Hicks, L. A., Pankey, G. A., Seleznick, M. J., Volturo, G., Wald, E. R., et al. (2012) · Clinical Infectious Diseases · doi:10.1093/cid/cis370 · Cited by 590 · see citing works
Self-citationEditors and Reviewers: Supporting Peer‐Review Publishing
Benninger, M. S. (2003) · Otolaryngology–Head and Neck Surgery · doi:10.1053/hn.2003.v128.amhn0312811 · Cited by 557 · see citing works
Otolaryngology‐Head and Neck Surgery
Meltzer, E. O., Hamilos, D. L., Hadley, J. A., Lanza, D. C., Marple, B. F., Nicklas, R. A., Bachert, C., Baraniuk, J. N., Baroody, F. M., Benninger, M. S., et al. (2004) · Otolaryngology · doi:10.1016/j.otohns.2004.09.067 · Cited by 557 · see citing works
Self-citationAntimicrobial Treatment Guidelines for Acute Bacterial Rhinosinusitis
Partnership, S. A. A. H. (2004) · Otolaryngology · doi:10.1016/j.otohns.2003.12.003 · Cited by 532 · see citing works
Wald, E. R., Applegate, K. E., Bordley, C., Darrow, D. H., Glode, M. P., Marcy, S. M., Nelson, C. E., Rosenfeld, R. M., Shaikh, N., Smith, M. J., et al. (2013) · PEDIATRICS · doi:10.1542/peds.2013-1071 · Cited by 530 · see citing works
Self-citationPractice parameter for the diagnosis and management of primary immunodeficiency
Bonilla, F. A., Bernstein, I. L., Khan, D. A., Ballas, Z. K., Chinen, J., Frank, M. M., Kobrynski, L. J., Levinson, A. I., Mazer, B. D., Nelson, R. P., et al. (2005) · Annals of Allergy Asthma & Immunology · doi:10.1016/s1081-1206(10)61142-8 · Cited by 518 · see citing works
Chow, A. W., Benninger, M. S., Brook, I., Brożek, J., Goldstein, E. J. C., Hicks, L. A., Pankey, G. A., Seleznick, M. J., Volturo, G., Wald, E. R., et al. (2012) · Clinical Infectious Diseases · doi:10.1093/cid/cir1043 · Cited by 504 · see citing works
Self-citationJarvis, D., Newson, R., Lotvall, J., Hastan, D., Tomassen, P., Keil, T., Gjomarkaj, M., Forsberg, B., Gunnbjornsdottir, M., Minov, J., et al. (2012) · Allergy · doi:10.1111/j.1398-9995.2011.02709.x · Cited by 485 · see citing works
Infections in 252 Patients with Common Variable Immunodeficiency
Oksenhendler, É., Gérard, L., Fieschi, C., Malphettes, M., Mouillot, G., Jaussaud, R., Viallard, J., Gardembas, M., Galicier, L., SCHLEINITZ, N., et al. (2008) · Clinical Infectious Diseases · doi:10.1086/587669 · Cited by 475 · see citing works
Jacobs, M. R. (2003) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkg321 · Cited by 469 · see citing works
Orange, J. S., Ballow, M. C., Stiehm, E. R., Ballas, Z. K., Chinen, J., de la Morena, M., Kumararatne, D. S., Harville, T., Hesterberg, P. E., Koleilat, M., et al. (2012) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2012.07.002 · Cited by 455 · see citing works
Antibiotics for the common cold and acute purulent rhinitis.
Arroll, B., & Kenealy, T. (2005) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd000247.pub2 · Cited by 439 · see citing works
Pharmacokinetics and pharmacodynamics of antibiotics in otitis media
Craig, W. A., & Andes, D. R. (1996) · The Pediatric Infectious Disease Journal · doi:10.1097/00006454-199603000-00015 · Cited by 438 · see citing works
Antibiotics for the common cold and acute purulent rhinitis
Kenealy, T. W., & Arroll, B. (2013) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd000247.pub3 · Cited by 434 · see citing works
Nasal polyps in asthma and rhinitis
Settipane, G. A., & Chafee, F. H. (1977) · Journal of Allergy and Clinical Immunology · doi:10.1016/0091-6749(77)90171-3 · Cited by 424 · see citing works
Acute Community-Acquired Sinusitis
Gwaltney, J. M. (1996) · Clinical Infectious Diseases · doi:10.1093/clinids/23.6.1209 · Cited by 413 · see citing works
Ray, N. F., Baraniuk, J. N., Thamer, M., et al. (1999) · Journal of Allergy and Clinical Immunology · doi:10.1016/s0091-6749(99)70464-1 · Cited by 390 · see citing works
Shiffman, R. N., Dixon, J. K., Brandt, C., Essaihi, A., Hsiao, A., Michel, G., & O’Connell, R. T. (2005) · BMC Medical Informatics and Decision Making · doi:10.1186/1472-6947-5-23 · Cited by 389 · see citing works
EAACI Position Paper on Rhinosinusitis and Nasal Polyps Executive Summary
Fokkens, W. J., Lund, V. J., Bachert, C., Clement, P. A. R., Helllings, P., Holmström, M., Jones, N. S., Kalogjera, L., Kennedy, D. W., Kowalski, M. L., et al. (2005) · Allergy · doi:10.1111/j.1398-9995.2005.00830.x · Cited by 384 · see citing works
Epidemiology and Economic Impact of Rhinosinusitis
Anand, V. K. (2004) · Annals of Otology Rhinology & Laryngology · doi:10.1177/00034894041130s502 · Cited by 380 · see citing works
The diagnosis and management of sinusitis: A practice parameter update
Slavin, R. G., Spector, S. L., Bernstein, I. L., Slavin, R. G., Kaliner, M., Kennedy, D. W., Virant, F. S., Wald, E. R., Khan, D. A., Blessing-Moore, J., et al. (2005) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2005.09.048 · Cited by 375 · see citing works
Antibiotic Selection Pressure and Resistance in Streptococcus pneumoniae and Streptococcus pyogenes
Albrich, W. C., Monnet, D. L., & Harbarth, S. (2004) · Emerging infectious diseases · doi:10.3201/eid1003.030252 · Cited by 374 · see citing works
Intracranial complications of paranasal sinusitis: A combined institutional review
Clayman, G. L., Adams, G. L., Paugh, D. R., & Koopmann, C. F. (1991) · The Laryngoscope · doi:10.1288/00005537-199103000-00003 · Cited by 348 · see citing works
Incremental Health Care Utilization and Expenditures for Chronic Rhinosinusitis in the United States
Bhattacharyya, N. (2011) · Annals of Otology Rhinology & Laryngology · doi:10.1177/000348941112000701 · Cited by 345 · see citing works
Rhinosinusitis in severe asthma
Bresciani, M., Paradis, L., Des Roches, A., Vernhet, H., Vachier, I., Godard, P., Bousquet, J., & Chanez, P. (2001) · Journal of Allergy and Clinical Immunology · doi:10.1067/mai.2001.111593 · Cited by 345 · see citing works
Rhinosinusitis: Developing guidance for clinical trials
Meltzer, E. O., Hamilos, D. L., Hadley, J. A., Lanza, D. C., Marple, B. F., Nicklas, R. A., Adinoff, A., Bachert, C., Borish, L., Chinchilli, V. M., et al. (2006) · Otolaryngology · doi:10.1016/j.otohns.2006.09.014 · Cited by 326 · see citing works
Classifying Recommendations for Clinical Practice Guidelines
Steering Committee on Quality Improvement and Management (2004) · Pediatrics · doi:10.1542/peds.2004-1260 · Cited by 322 · see citing works
Concerning the nature of intolerance to aspirin
Samter, M., & Beers, R. F. (1967) · Journal of Allergy · doi:10.1016/0021-8707(67)90076-7 · Cited by 319 · see citing works
Prevalence of Incidental Abnormalities on Computed Tomographic Scans of the Paranasal Sinuses
Havas, T. E., Motbey, J., & Gullane, P. J. (1988) · Archives of Otolaryngology - Head and Neck Surgery · doi:10.1001/archotol.1988.01860200040012 · Cited by 317 · see citing works
Canadian clinical practice guidelines for acute and chronic rhinosinusitis
Desrosiers, M., Evans, G. A., Keith, P. K., Wright, E. D., Kaplan, A., Bouchard, J., Ciavarella, A., Doyle, P. W., Javer, A. R., Leith, E. S., et al. (2011) · Allergy, Asthma & Clinical Immunology · doi:10.1186/1710-1492-7-2 · Cited by 313 · see citing works
Chronic sinusitis in severe asthma is related to sputum eosinophilia
ten Brinke, A., Grootendorst, D. C., Schmidt, J. T., de Bruïne, F. T., van Buchem, M. A., Sterk, P. J., Rabe, K. F., & Bel, E. H. (2002) · Journal of Allergy and Clinical Immunology · doi:10.1067/mai.2002.122458 · Cited by 311 · see citing works
Thornsberry, C., Jones, M. E., Hickey, M. L., et al. (1999) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/44.6.749 · Cited by 300 · see citing works
Ambrose, P. G., Grasela, D. M., Grasela, T. H., Passarell, J. A., Mayer, H., & Pierce, P. F. (2001) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.45.10.2793-2797.2001 · Cited by 299 · see citing works
(2020) · American Academy of Pediatrics eBooks · doi:10.1542/9781610024358-part05-ch16 · Cited by 295 · see citing works
Newman, L. J. (1994) · JAMA · doi:10.1001/jama.271.5.363 · Cited by 293 · see citing works
Clinical Study and Literature Review of Nasal Irrigation
Tomooka, L. T., Murphy, C., & Davidson, T. M. (2000) · The Laryngoscope · doi:10.1097/00005537-200007000-00023 · Cited by 286 · see citing works
Chronic rhinosinusitis: An enhanced immune response to ubiquitous airborne fungi
Shin, S., Ponikau, J. U., Sherris, D. A., Congdon, D. J., Frigas, E., Homburger, H. A., Swanson, M. C., Gleich, G. J., & Kita, H. (2004) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2004.08.012 · Cited by 276 · see citing works
Schreiber, C. P., Hutchinson, S. L., Webster, C. J., Ames, M. H., Richardson, M. S., & Powers, C. (2004) · Archives of Internal Medicine · doi:10.1001/archinte.164.16.1769 · Cited by 276 · see citing works
Choosing Wisely: Prevalence and Correlates of Low-Value Health Care Services in the United States
Colla, C. H., Morden, N. E., Sequist, T. D., Schpero, W. L., & Rosenthal, M. B. (2014) · Journal of General Internal Medicine · doi:10.1007/s11606-014-3070-z · Cited by 275 · see citing works
Nuorti, J. P., Butler, J. C., Crutcher, J. M., Guevara, R. E., Welch, D., Holder, P. F., & Elliott, J. A. (1998) · New England Journal of Medicine · doi:10.1056/nejm199806253382601 · Cited by 270 · see citing works
Gwaltney, J. M., Scheld, W. M., Sande, M. A., & Sydnor, A. (1992) · Journal of Allergy and Clinical Immunology · doi:10.1016/0091-6749(92)90169-3 · Cited by 264 · see citing works
Incidence and associated premorbid diagnoses of patients with chronic rhinosinusitis
Tan, B. K., Chandra, R. K., Pollak, J., Kato, A., Conley, D. B., Peters, A. T., Grammer, L. C., Avila, P. C., Kern, R. C., Stewart, W. F., et al. (2013) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2013.02.002 · Cited by 256 · see citing works
Self-citationBhattacharyya, T., Piccirillo, J. F., & Wippold, F. J. (1997) · Archives of Otolaryngology - Head and Neck Surgery · doi:10.1001/archotol.1997.01900110039006 · Cited by 254 · see citing works
Self-citationBernstein, I. L., & Ww, S. (1995) · PubMed · Cited by 248 · see citing works
Rhinosinusitis Diagnosis and Management for the Clinician: A Synopsis of Recent Consensus Guidelines
Meltzer, E. O., & Hamilos, D. L. (2011) · Mayo Clinic Proceedings · doi:10.4065/mcp.2010.0392 · Cited by 246 · see citing works
Younis, R. T., Anand, V. K., & Davidson, B. L. (2002) · The Laryngoscope · doi:10.1097/00005537-200202000-00005 · Cited by 239 · see citing works
Meltzer, E. O., Bachert, C., & Staudinger, H. W. (2005) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2005.08.044 · Cited by 238 · see citing works
Settipane, G. A. (1996) · Allergy and Asthma Proceedings · doi:10.2500/108854196778662246 · Cited by 234 · see citing works
Principles of Appropriate Antibiotic Use for Acute Rhinosinusitis in Adults: Background
Hickner, J. M., Bartlett, J. G., Besser, R. E., Gonzales, R., Hoffman, J. R., & Sande, M. A. (2001) · Annals of Internal Medicine · doi:10.7326/0003-4819-134-6-200103200-00017 · Cited by 234 · see citing works
Hissaria, P., Smith, W., Wormald, P. J., Taylor, J. H., Vadas, M. A., Gillis, D., & Kette, F. E. (2006) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2006.03.012 · Cited by 231 · see citing works
Clinical Evaluation for Sinusitis
Williams, J. W., Simel, D. L., Roberts, L., & Samsa, G. (1992) · Annals of Internal Medicine · doi:10.7326/0003-4819-117-9-705 · Cited by 230 · see citing works
Productivity costs in patients with refractory chronic rhinosinusitis
Rudmik, L. R., Smith, T. L., Schlosser, R. J., Hwang, P. H., Mace, J. C., & Soler, Z. M. (2014) · The Laryngoscope · doi:10.1002/lary.24630 · Cited by 228 · see citing works
Saline nasal irrigation for acute upper respiratory tract infections
King, D., Mitchell, B., Williams, C. P., & Spurling, G. K. (2015) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd006821.pub3 · Cited by 226 · see citing works
Clinical Practice Guideline Development Manual, Third Edition
Rosenfeld, R. M., Shiffman, R. N., & Robertson, P. (2012) · Otolaryngology · doi:10.1177/0194599812467004 · Cited by 226 · see citing works
Self-citationBSACI guidelines for the management of rhinosinusitis and nasal polyposis
Scadding, G. K., Durham, S. R., Mirakian, R. M., Jones, N. S., Drake‐Lee, A., Ryan, D. P., Dixon, T. A., Huber, P. A. J., & Nasser, S. M. (2007) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.2007.02889.x · Cited by 225 · see citing works
Pearlman, A. N., Chandra, R. K., Conley, D. B., et al. (2010) · Springer eBooks · doi:10.1007/978-3-642-11412-0_2 · Cited by 224 · see citing works
Newman, L. J. (1994) · JAMA · doi:10.1001/jama.1994.03510290045035 · Cited by 222 · see citing works
Young, J., Sutter, A. D., Merenstein, D., van Essen, G. A., Kaiser, L., Varonen, H., Williamson, I. G., & Bucher, H. C. (2008) · The Lancet · doi:10.1016/s0140-6736(08)60416-x · Cited by 221 · see citing works
Association between Severity of Asthma and Degree of Chronic Rhinosinusitis
Lin, D. C., Chandra, R. K., Tan, B. K., Zirkle, W., Conley, D. B., Grammer, L. C., Kern, R. C., Schleimer, R. P., & Peters, A. T. (2011) · American Journal of Rhinology and Allergy · doi:10.2500/ajra.2011.25.3613 · Cited by 216 · see citing works
Self-citationNava, J. M., Bella, F., Garau, J., Lite, J., Morera, M., Martí, C. D., Fontanals, D., Font, B., Solas, V. P., Úriz, S., et al. (1994) · Clinical Infectious Diseases · doi:10.1093/clinids/19.5.884 · Cited by 215 · see citing works
The Accuracy of Computed Tomography in the Diagnosis of Chronic Rhinosinusitis
Bhattacharyya, N., & Fried, M. P. (2003) · The Laryngoscope · doi:10.1097/00005537-200301000-00023 · Cited by 214 · see citing works
Effectiveness of the new serotypes in the 13-valent pneumococcal conjugate vaccine
Miller, E., Andrews, N. J., Waight, P. A., Slack, M., & George, R. C. (2011) · Vaccine · doi:10.1016/j.vaccine.2011.09.112 · Cited by 205 · see citing works
Clinical and Symptom Criteria for the Accurate Diagnosis of Chronic Rhinosinusitis
Bhattacharyya, N. (2006) · The Laryngoscope · doi:10.1097/01.mlg.0000224508.59725.19 · Cited by 202 · see citing works
Lildholdt, T., Rundcrantz, H., & Lindqvist, N. (1995) · Clinical Otolaryngology · doi:10.1111/j.1365-2273.1995.tb00007.x · Cited by 202 · see citing works
Health state utility values in patients undergoing endoscopic sinus surgery
Soler, Z. M., Wittenberg, E., Schlosser, R. J., Mace, J. C., & Smith, T. L. (2011) · The Laryngoscope · doi:10.1002/lary.21847 · Cited by 202 · see citing works
Imaging of Rhinosinusitis and Its Complications: Plain Film, CT, and MRI
Mafee, M. F., Tran, B. H., & Chapa, A. R. (2006) · Clinical Reviews in Allergy & Immunology · doi:10.1385/criai:30:3:165 · Cited by 199 · see citing works
Rabago, D., Zgierska, A. E., Mundt, M. P., Barrett, B. P., Bobula, J. A., & Maberry, R. (2002) · PubMed · Cited by 198 · see citing works
Concordant genotype of upper and lower airways P aeruginosa and S aureus isolates in cystic fibrosis
Mainz, J. G., Naehrlich, L., Schien, M., Käding, M., Schiller, I., Mayr, S., Schneider, G., Wiedemann, B., Wiehlmann, L., Cramer, N., et al. (2009) · Thorax · doi:10.1136/thx.2008.104711 · Cited by 194 · see citing works
Allergy in patients with acute maxillary sinusitis
Savolainen, S. (1989) · Allergy · doi:10.1111/j.1398-9995.1989.tb02234.x · Cited by 176 · see citing works
Rudmik, L. R., Hoy, M. Y., Schlosser, R. J., Harvey, R. J., Welch, K. C., Lund, V. J., & Smith, T. L. (2012) · International Forum of Allergy & Rhinology · doi:10.1002/alr.21096 · Cited by 175 · see citing works
Cost Burden of Chronic Rhinosinusitis
Bhattacharyya, N., Orlandi, R. R., Grebner, J., & Martinson, M. (2011) · Otolaryngology · doi:10.1177/0194599810391852 · Cited by 174 · see citing works
Self-citationNasal Saline for Chronic Sinonasal Symptoms
Pynnonen, M. A., Mukerji, S. S., Kim, H. M., Adams, M. E., & Terrell, J. E. (2007) · Archives of Otolaryngology - Head and Neck Surgery · doi:10.1001/archotol.133.11.1115 · Cited by 170 · see citing works
Etiology and Antimicrobial Treatment of Acute Sinusitis
Gwaltney, J. M., Sydnor, A., & Sande, M. A. (1981) · Annals of Otology Rhinology & Laryngology · doi:10.1177/00034894810903s216 · Cited by 169 · see citing works
Clinical Profile and recurrence of nasal polyps
Drake‐Lee, A., Lowe, D., Swanston, A. R., et al. (1984) · The Journal of Laryngology & Otology · doi:10.1017/s0022215100147462 · Cited by 166 · see citing works
Gwaltney, J. M. (1967) · JAMA · doi:10.1001/jama.202.6.494 · Cited by 166 · see citing works
Sahm, D. F., Jones, M. E., Hickey, M. L., et al. (2000) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/45.4.457 · Cited by 162 · see citing works
Treatment of chronic rhinosinusitis and its effects on asthma
Ragab, S. M., Scadding, G. K., Lund, V. J., & Saleh, H. A. (2006) · European Respiratory Journal · doi:10.1183/09031936.06.00043305 · Cited by 160 · see citing works
Antibiotics and Topical Nasal Steroid for Treatment of Acute Maxillary Sinusitis
Williamson, I. G., Rumsby, K., Benge, S., Moore, M. V., Smith, P. W. F., Cross, M., & Little, P. S. (2007) · JAMA · doi:10.1001/jama.298.21.2487 · Cited by 160 · see citing works
Chronic rhinosinusitis: Allergy and sinus computed tomography relationships
井上, 英., & Shah, S. B. (2000) · Otolaryngology · doi:10.1067/mhn.2000.110961 · Cited by 159 · see citing works
Meltzer, E. O., Charous, B. L., Busse, W. W., Zinreich, S. J., Lorber, R. R., & Danzig, M. R. (2000) · Journal of Allergy and Clinical Immunology · doi:10.1067/mai.2000.109056 · Cited by 158 · see citing works
DelGaudio, J. M. (2005) · The Laryngoscope · doi:10.1097/01.mlg.0000163751.00885.63 · Cited by 158 · see citing works
Intranasal Budesonide Spray as an Adjunct to Oral Antibiotic Therapy for Acute Sinusitis in Children
Barlan, I. B., Erkan, E., Bakır, M., Berrak, S. G., & Başaran, M. M. (1997) · Annals of Allergy Asthma & Immunology · doi:10.1016/s1081-1206(10)63223-1 · Cited by 152 · see citing works
Outpatient Use of Erythromycin: Link to Increased Erythromycin Resistance in Group A Streptococci
Seppälä, H., Klaukka, T., Lehtonen, R., NENONEN, E., Finnish Study Group for Antimicrobial Resistance, & Huovinen, P. (1995) · Clinical Infectious Diseases · doi:10.1093/clinids/21.6.1378 · Cited by 152 · see citing works
Intranal flunisolide spray as an adjunct to oral antibiotic therapy for sinusitis
Meltzer, E. O., Orgel, H. A., BACKHAUS, J., Busse, W. W., Druce, H. M., Metzger, W. J., Mitchell, D. Q., Seiner, J. C., Shapiro, G. G., Bavel, J. H. V., et al. (1993) · Journal of Allergy and Clinical Immunology · doi:10.1016/0091-6749(93)90058-n · Cited by 148 · see citing works
Sources of bias for authors of clinical practice guidelines
Detsky, A. S. (2006) · Canadian Medical Association Journal · doi:10.1503/cmaj.061181 · Cited by 147 · see citing works
Radiologic Correlates of Symptom‐Based Diagnostic Criteria for Chronic Rhinosinusitis
Hwang, P. H., Irwin, S. B., Griest, S. E., Caro, J. E., & Nesbit, G. M. (2003) · Otolaryngology · doi:10.1016/s0194-5998(02)23295-7 · Cited by 147 · see citing works
Perennial allergic rhinitis and chronic sinusitis: correlation with rhinologic risk factors
Berrettini, S., Carabelli, A., Sellari‐Franceschini, S., Bruschini, L., Quartieri, F., Sconosciuto, F., & Abruzzese, A. (1999) · Allergy · doi:10.1034/j.1398-9995.1999.00813.x · Cited by 145 · see citing works
A practical guide for the diagnosis and treatment of acute sinusitis.
Low, D. E., Desrosiers, M. Y., McSherry, J., et al. (1997) · PubMed · Cited by 145 · see citing works
Principles of Appropriate Antibiotic Use for Acute Sinusitis in Adults
Snow, V. T., Mottur-Pilson, C., & Hickner, J. M. (2001) · Annals of Internal Medicine · doi:10.7326/0003-4819-134-6-200103200-00016 · Cited by 144 · see citing works
Wilson, K. F., McMains, K. C., & Orlandi, R. R. (2014) · International Forum of Allergy & Rhinology · doi:10.1002/alr.21258 · Cited by 143 · see citing works
Self-citationAnalysis of Symptoms and Clinical Signs in the Maxillary Sinus Empyema
Berg, O., & Carenfelt, C. (1988) · Acta Oto-Laryngologica · doi:10.3109/00016488809097017 · Cited by 143 · see citing works
Are nasal polyps an allergic phenomenon?
Caplin, I., Jt, H., & Spahn, J. (1971) · PubMed · Cited by 143 · see citing works
Rhinovirus Infections in an Industrial Population
Gwaltney, J. M. (1967) · JAMA · doi:10.1001/jama.1967.03130190100014 · Cited by 143 · see citing works
Evaluating the diagnosis of chronic rhinosinusitis based on clinical guidelines and endoscopy
Bhattacharyya, N., & Lee, L. N. (2010) · Otolaryngology · doi:10.1016/j.otohns.2010.04.012 · Cited by 142 · see citing works
Nasal Endoscopy and the Definition and Diagnosis of Chronic Rhinosinusitis
Stankiewicz, J. A., & Chow, J. M. (2002) · Otolaryngology · doi:10.1067/mhn.2002.125602 · Cited by 139 · see citing works
Ponikau, J. U., Sherris, D. A., Kephart, G. M., Kern, E. B., Congdon, D. J., Adolphson, C. R., Springett, M. J., Gleich, G. J., & Kita, H. (2005) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2005.03.049 · Cited by 139 · see citing works
Poetker, D. M., Jakubowski, L. A., Lal, D., Hwang, P. H., Wright, E. D., & Smith, T. L. (2012) · International Forum of Allergy & Rhinology · doi:10.1002/alr.21072 · Cited by 137 · see citing works
A systematic review of the use of intranasal steroids in the treatment of chronic rhinosinusitis
Joe, S. A., Thambi, R., & Huang, J. (2008) · Otolaryngology–Head and Neck Surgery · doi:10.1016/j.otohns.2008.05.628 · Cited by 136 · see citing works
Lindbæk, M., Hjortdahl, P., & Johnsen, U. L.-H. (1996) · PubMed · Cited by 135 · see citing works
Immune Dysfunction in Refractory Sinusitis in a Tertiary Care Setting
Chee, L. W. J., Graham, S. M., Carothers, D. G., & Ballas, Z. K. (2001) · The Laryngoscope · doi:10.1097/00005537-200102000-00008 · Cited by 134 · see citing works
Prospective Analysis of Sinus Symptoms and Correlation with Paranasal Computed Tomography Scan
Kenny, T. J., Duncavage, J. A., Bracikowski, J. P., Yıldırım, A., MURRAY, J. J., & Tanner, S. B. (2001) · Otolaryngology · doi:10.1067/mhn.2001.116779 · Cited by 132 · see citing works
Aukema, A. A. C., Mulder, P. G. H., & Fokkens, W. J. (2005) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2004.12.1144 · Cited by 130 · see citing works
Systemic corticosteroids for acute sinusitis
Venekamp, R. P., Thompson, M., Hayward, G., Heneghan, C. J., Mar, C. D., Perera, R., Glasziou, P., & Rovers, M. M. (2014) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd008115.pub3 · Cited by 126 · see citing works
National burden of antibiotic use for adult rhinosinusitis
Smith, S. S., Evans, C. T., Tan, B. K., Chandra, R. K., Smith, S. B., & Kern, R. C. (2013) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2013.07.009 · Cited by 123 · see citing works
Virgin, F. W., Rowe, S. M., Wade, M. B., Gaggar, A., Leon, K. J., Young, K. R., & Woodworth, B. A. (2012) · American Journal of Rhinology and Allergy · doi:10.2500/ajra.2012.26.3705 · Cited by 119 · see citing works
A Clinical Trial of Hypertonic Saline Nasal Spray in Subjects With the Common Cold or Rhinosinusitis
Adam, P. (1998) · Archives of Family Medicine · doi:10.1001/archfami.7.1.39 · Cited by 118 · see citing works
Benninger, M. S., Payne, S. C., Ferguson, B. J., Hadley, J. A., & Ahmad, N. (2006) · Otolaryngology · doi:10.1016/j.otohns.2005.10.010 · Cited by 118 · see citing works
Preston, S. L., Drusano, G. L., Berman, A. L., Fowler, C. L., Chow, A. T., Dornseif, B. E., Reichl, V., Natarajan, J., Wong, F. A., & Corrado, M. L. (1998) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.42.5.1098 · Cited by 117 · see citing works
Alkire, B. C., & Bhattacharyya, N. (2010) · The Laryngoscope · doi:10.1002/lary.20804 · Cited by 117 · see citing works
Intranasal steroids for acute sinusitis
Trestioreanu, A. Z., & Yaphe, J. (2013) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd005149.pub4 · Cited by 116 · see citing works
Taylor, M. J., Ponikau, J. U., Sherris, D. A., Kern, E. B., Gaffey, T. A., Kephart, G. M., & Kita, H. (2002) · Otolaryngology · doi:10.1067/mhn.2002.128896 · Cited by 112 · see citing works
Mortuaire, G., de Gabory, L. L. T., Francois, M., Massé, G., Bloch, F., Brion, N., Jankowski, R., & Serrano, É. (2013) · European Annals of Otorhinolaryngology Head and Neck Diseases · doi:10.1016/j.anorl.2012.09.005 · Cited by 112 · see citing works
Ikeda, K., Tamura, G., Shimomura, A., Suzuki, H., Nakabayashi, S., Tanno, N., Oshima, T., & Takasaka, T. (1999) · Annals of Otology Rhinology & Laryngology · doi:10.1177/000348949910800407 · Cited by 111 · see citing works
Harrison, C. J., Woods, C., Stout, G., et al. (2009) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkn538 · Cited by 110 · see citing works
Atopic profile of patients failing medical therapy for chronic rhinosinusitis
Tan, B. K., Zirkle, W., Chandra, R. K., Lin, D. C., Conley, D. B., Peters, A. T., Grammer, L. C., Schleimer, R. P., & Kern, R. C. (2011) · International Forum of Allergy & Rhinology · doi:10.1002/alr.20025 · Cited by 109 · see citing works
Self-citationBenitez, P. A., Alobid, I., de Haro, J., et al. (2006) · The Laryngoscope · doi:10.1097/01.mlg.0000205218.37514.0f · Cited by 109 · see citing works
Steinke, D. T., & Davey, P. G. (2001) · Clinical Infectious Diseases · doi:10.1086/321848 · Cited by 109 · see citing works
Falagas, M., Giannopoulou, K., Vardakas, K., Dimopoulos, G., & Karageorgopoulos, D. (2008) · Lancet. Infectious Diseases (Print) · doi:10.1016/s1473-3099(08)70202-0 · Cited by 109 · see citing works
Characteristics of Bony Erosion in Allergic Fungal Rhinosinusitis
Nussenbaum, B. A., Marple, B. F., & Schwade, N. D. (2001) · Otolaryngology · doi:10.1067/mhn.2001.112573 · Cited by 107 · see citing works
A Comparison of Symptom Scores and Radiographic Staging Systems in Chronic Rhinosinusitis
Bhattacharyya, N. (2005) · American Journal of Rhinology · doi:10.1177/194589240501900210 · Cited by 106 · see citing works
Vashishta, R., Soler, Z. M., Nguyen, S. A., & Schlosser, R. J. (2013) · International Forum of Allergy & Rhinology · doi:10.1002/alr.21182 · Cited by 106 · see citing works
Diagnosis and treatment of acute bacterial rhinosinusitis.
Lau, J., Zucker, D. R., Engels, E. A., et al. (1999) · PubMed · Cited by 106 · see citing works
Corticosteroid Treatment in Chronic Rhinosinusitis: The Possibilities and the Limits
Mullol, J., Obando, A., Pujols, L., & Alobid, I. (2009) · Immunology and Allergy Clinics of North America · doi:10.1016/j.iac.2009.07.001 · Cited by 105 · see citing works
Cady, R. K., Dodick, D. W., Levine, H. L., et al. (2005) · Mayo Clinic Proceedings · doi:10.4065/80.7.908 · Cited by 105 · see citing works
Cowan, M. J., Gladwin, M. T., & Shelhamer, J. H. (2001) · The American Journal of the Medical Sciences · doi:10.1097/00000441-200101000-00002 · Cited by 103 · see citing works
Nasal Pepsin Assay and pH Monitoring in Chronic Rhinosinusitis
Özmen, S., Yücel, Ö. T., Lay, İ., Özmen, Ö. A., Süslü, A. E., Öǧretmenoǧlu, O., & Önerci, M. (2008) · The Laryngoscope · doi:10.1097/mlg.0b013e318165e324 · Cited by 101 · see citing works
Recurrent Acute Rhinosinusitis
Bhattacharyya, N., Grebner, J., & Martinson, N. G. (2011) · Otolaryngology · doi:10.1177/0194599811426089 · Cited by 99 · see citing works
Lange, B., Holst, R., Thilsing, T., Bælum, J., & Kjeldsen, A. D. (2013) · Clinical Otolaryngology · doi:10.1111/coa.12189 · Cited by 99 · see citing works
Antibiotics for clinically diagnosed acute rhinosinusitis in adults
Lemiengre, M. B., van Driel, M., Merenstein, D., Young, J., & Sutter, A. I. D. (2012) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd006089.pub4 · Cited by 99 · see citing works
Does the Severity of Sinus Computed Tomography Findings Predict Outcome in Chronic Sinusitis?
Stewart, M. G., Donovan, D. T., Parke, R. B., et al. (2000) · Otolaryngology · doi:10.1067/mhn.2000.105922 · Cited by 96 · see citing works
Correlation of Allergy and Severity of Sinus Disease
Ramadan, H. H., Fornelli, R. A., Ortiz, A. O., & Rodman, S. M. (1999) · American Journal of Rhinology · doi:10.2500/105065899781367500 · Cited by 96 · see citing works
ACR Appropriateness Criteria ® Sinonasal Disease
Kirsch, C., Bykowski, J., Aulino, J. M., et al. (2017) · Journal of the American College of Radiology · doi:10.1016/j.jacr.2017.08.041 · Cited by 95 · see citing works
Computed Tomography Stage, Allergy Testing, and Quality of Life in Patients with Sinusitis
Krouse, J. H. (2000) · Otolaryngology · doi:10.1067/mhn.2000.109476 · Cited by 95 · see citing works
Pharyngeal acid Reflux in Patients with Single and Multiple Otolaryngologic Disorders
Ulualp, S. O., Toohill, R. J., & Shaker, R. (1999) · Otolaryngology · doi:10.1053/hn.1999.v121.a98010 · Cited by 93 · see citing works
Soler, Z. M., Oyer, S. L., Kern, R. C., Senior, B. A., Kountakis, S. E., Marple, B. F., & Smith, T. L. (2012) · International Forum of Allergy & Rhinology · doi:10.1002/alr.21064 · Cited by 93 · see citing works
Imaging for Staging of Rhinosinusitis
Zinreich, S. J. (2004) · Annals of Otology Rhinology & Laryngology · doi:10.1177/00034894041130s506 · Cited by 92 · see citing works
Ioannidis, J. P. A. (2001) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/48.5.677 · Cited by 88 · see citing works
Staphylococcus aureus Is a Major Pathogen in Acute Bacterial Rhinosinusitis: A Meta-Analysis
Payne, S. C., & Benninger, M. S. (2007) · Clinical Infectious Diseases · doi:10.1086/522763 · Cited by 88 · see citing works
Rhinosinusitis in cystic fibrosis: Not a simple story
Babiński, D., & Trawinska-Bartnicka, M. (2008) · International Journal of Pediatric Otorhinolaryngology · doi:10.1016/j.ijporl.2008.01.010 · Cited by 85 · see citing works
Zurlo, J. J., Feuerstein, I. M., Lebovics, R. S., et al. (1992) · The American Journal of Medicine · doi:10.1016/0002-9343(92)90045-d · Cited by 85 · see citing works
Effects of Buffered Saline Solution on Nasal Mucociliary Clearance and Nasal Airway Patency
Keojampa, B. K., Nguyen, M. H., & Ryan, M. W. (2004) · Otolaryngology · doi:10.1016/j.otohns.2004.05.026 · Cited by 84 · see citing works
Long‐term utility outcomes in patients undergoing endoscopic sinus surgery
Rudmik, L. R., Mace, J. C., Soler, Z. M., & Smith, T. L. (2013) · The Laryngoscope · doi:10.1002/lary.24135 · Cited by 83 · see citing works
Saline nasal irrigation for acute upper respiratory tract infections
Kassel, J. C., King, D. B., & Spurling, G. (2010) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd006821.pub2 · Cited by 82 · see citing works
The clinical diagnosis of acute purulent sinusitis in general practice--a review.
Lindbæk, M., & Hjortdahl, P. (2002) · PubMed · Cited by 81 · see citing works
Adjunct effect of loratadine in the treatment of acute sinusitis in patients with allergic rhinitis
Braun, J. J., Alabert, J. P., Michel, F. B., Quiniou, M.-J., Rat, C., Cougnard, J., Czarlewski, W., & Bousquet, J. (1997) · Allergy · doi:10.1111/j.1398-9995.1997.tb01044.x · Cited by 79 · see citing works
Use of topical nasal therapies in the management of Chronic rhinosinusitis
Wei, C. C., Adappa, N. D., & Cohen, N. A. (2013) · The Laryngoscope · doi:10.1002/lary.24066 · Cited by 78 · see citing works
Eccles, R., Jawad, M., Jawad, S., Angello, J. T., & Druce, H. M. (2005) · American Journal of Rhinology · doi:10.1177/194589240501900105 · Cited by 77 · see citing works
Prospects for ancillary treatment of sinusitis in the 1990s
Zeiger, R. S. (1992) · Journal of Allergy and Clinical Immunology · doi:10.1016/0091-6749(92)90173-y · Cited by 77 · see citing works
Brook, I., Foote, P. A., & Hausfeld, J. N. (2006) · Journal of Medical Microbiology · doi:10.1099/jmm.0.46346-0 · Cited by 77 · see citing works
Self-citationOccurrence of asymptomatic sinusitis in common cold and other acute ENT-infections.
Berg, O., Carenfelt, C., Rystedt, G., & Änggård, A. (1986) · PubMed · Cited by 77 · see citing works
Sinusitis in an Allergist's Office: Analysis of 200 Consecutive Cases
MCNALLY, P., White, M. V., & Kaliner, M. (1997) · Allergy and Asthma Proceedings · doi:10.2500/108854197778984374 · Cited by 76 · see citing works
Bacteriology of Maxillary Sinusitis in Relation to Character of Inflammation and Prior Treatment
Berg, O., Carenfelt, C., & Kronvall, G. (1988) · Scandinavian Journal of Infectious Diseases · doi:10.3109/00365548809032499 · Cited by 74 · see citing works
Falagas, M. E., Karageorgopoulos, D. E., Grammatikos, A. P., & Matthaiou, D. K. (2008) · British Journal of Clinical Pharmacology · doi:10.1111/j.1365-2125.2008.03306.x · Cited by 74 · see citing works
Antimicrobial treatment in acute maxillary sinusitis: A meta-analysis
de Bock, G. H., Dekker, F. W., Stolk, J. N., et al. (1997) · Journal of Clinical Epidemiology · doi:10.1016/s0895-4356(97)00117-0 · Cited by 74 · see citing works
A prospective analysis of incidental paranasal sinus abnormalities on CT head scans
FLINN, J. W., Chapman, M., Wightman, A. J. A., et al. (1994) · Clinical Otolaryngology · doi:10.1111/j.1365-2273.1994.tb01232.x · Cited by 73 · see citing works
Carr, T. F., Koterba, A. P., Chandra, R. K., Grammer, L. C., Conley, D. B., Harris, K. E., Kern, R. C., Schleimer, R. P., & Peters, A. T. (2011) · American Journal of Rhinology and Allergy · doi:10.2500/ajra.2011.25.3653 · Cited by 73 · see citing works
Self-citationCritchley, I. A., Brown, S. D., Traczewski, M. M., et al. (2007) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00971-07 · Cited by 73 · see citing works
Benninger, M. S., Appelbaum, P. C., Denneny, J. C., et al. (2002) · Otolaryngology · doi:10.1067/mhn.2002.124847 · Cited by 72 · see citing works
Lacroix, J. S., Ricchetti, A., Lew, D., Delhumeau, C., Morabia, A., Stalder, H., Terrier, F., & Kaiser, L. (2002) · Acta Oto-Laryngologica · doi:10.1080/00016480252814216 · Cited by 72 · see citing works
Gastroesophageal Reflux Disease and Chronic Sinusitis: In Search of an Esophageal–nasal Reflex
Wong, I., Rees, G. L., Greiff, L., Myers, J. C., Jamieson, G. G., & Wormald, P. (2010) · American Journal of Rhinology and Allergy · doi:10.2500/ajra.2010.24.3490 · Cited by 71 · see citing works
The Role of Ubiquitous Airborne Fungi in Chronic Rhinosinusitis
Ponikau, J. U., Sherris, D. A., Kephart, G. M., Adolphson, C. R., & Kita, H. (2006) · Clinical Reviews in Allergy & Immunology · doi:10.1385/criai:30:3:187 · Cited by 71 · see citing works
Treatment of Sinus Headache as Migraine: The Diagnostic Utility of Triptans
Kari, E., & DelGaudio, J. M. (2008) · The Laryngoscope · doi:10.1097/mlg.0b013e318182f81d · Cited by 70 · see citing works
ACR Appropriateness Criteria Sinonasal Disease
Cornelius, R. S., Martin, J., Wippold, F. J., et al. (2013) · Journal of the American College of Radiology · doi:10.1016/j.jacr.2013.01.001 · Cited by 70 · see citing works
Upper and lower airway cultures in children with cystic fibrosis: Do not neglect the upper airways
Bonestroo, H. J. C., Groot, K. M. D. W., van der Ent, C. K., et al. (2010) · Journal of Cystic Fibrosis · doi:10.1016/j.jcf.2010.01.001 · Cited by 69 · see citing works
Aanæs, K., von Buchwald, C., Hjuler, T., Skov, M., Alanin, M. C., & Johansen, H. K. (2013) · American Journal of Rhinology and Allergy · doi:10.2500/ajra.2013.27.3829 · Cited by 67 · see citing works
Setzen, G., Ferguson, B. J., Han, J. K., Rhee, J. S., Cornelius, R. S., Froum, S., Gillman, G. S., Houser, S. M., Krakovitz, P. R., Monfared, A. S., et al. (2012) · Otolaryngology · doi:10.1177/0194599812463848 · Cited by 67 · see citing works
Self-citationH1-Antihistamines and the Central Nervous System
Welch, M. J. (2002) · CRC Press eBooks · doi:10.3109/9780203910375-16 · Cited by 66 · see citing works
Complications of Acute Sinusitis in Children
Maija Hytönen, T. A. (2000) · Acta Oto-Laryngologica · doi:10.1080/000164800454260 · Cited by 66 · see citing works
Nanl, S., Öztürk, Ö., Korkmaz, M., Tutkun, A., & Batman, Ç. (2002) · The Laryngoscope · doi:10.1097/00005537-200202000-00022 · Cited by 66 · see citing works
Cheng, Y. K., Decker, P. A., O’Byrne, M. M., et al. (2006) · Annals of Allergy Asthma & Immunology · doi:10.1016/s1081-1206(10)60794-6 · Cited by 64 · see citing works
Mudgil, S. P., Wise, S. W., Hopper, K. D., Kasales, C. J., Mauger, D. T., & Fornadley, J. A. (2002) · Annals of Allergy Asthma & Immunology · doi:10.1016/s1081-1206(10)62000-5 · Cited by 64 · see citing works
Flagged first, then by citations
Research works printed but not linked: 12
- [21]21. bronchitis, and community-acquired pneumonia. Clin Ther . 2004;26:2153-2162.
- [41]41. Bronzwaer SL, Cars O, Buchholz U, et al. A European study on the relationship between antimicrobial use and antimicrobial resistance. Emerg Infect Dis . 2002;8:278-282.
- [59]59. Fokkens WJ, Lund VJ, Mullol J, et al. European position paper on rhinosinusitis and nasal polyps. Rhinology Suppl . 2012;23:1-298.
- [20]20. of rhinosinusitis. The CAFFS Trial: a randomized controlled trial. JAMA . 2001;286:3097-3105.
- [131]131. Ah-see K. Sinusitis (acute). Clin Evidence . 2006;15:1-11.
- [144]144. Brook I, Gober AE. Resistance to antibiotics used for therapy of otitis media and sinusitis: effect of previous antimicrobial therapy and smoking. Ann Otol Rhinol Laryngol . 1999;108:645647.
- [150]150. Craig WA. Pharmacokinetic/pharmacodynamic parameters: rationale for antibacterial dosing of mice and men. Clin Infect Dis . 1998;26:1-11.
- [181]181. Jarvis D, Newson R, Lotvall J, et al. Asthma in adults and its association with chronic rhinosinusitis: the GA2LEN survey in Europe. Allergy . 2012;67:91-98.
- [188]188. Gysin C, Alothman GA, Papsin BC. Sinonasal disease in cystic fibrosis: clinical characteristics, diagnosis, and management. Pediatr Pulmonol . 2000;30:481-489.
- [232]232. Van Dishoeck HAE. Allergy and infection of paranasal sinus. Adv Otolaryngol . 1961;10:1-29.
- [247]247. Lange B, Holst R, Thilsing T, et al. Quality of life and associated factors in persons with chronic rhinosinusitis in the general population. Clin Otolaryngol . 2013;38(6):474-480.
- [272]272. Scadding GK, Durham SR, Mirakian R, et al. BSACI guidelines for the management of rhinosinusitis and nasal polyposis. Clin Exp Allergy . 2008;38:260-275.
Cited by
Sorted by citations
Prevalence of inappropriate antibiotic prescriptions among US ambulatory care visits, 2010-2011
Fleming-Dutra, K. E., Hersh, A. L., Shapiro, D. J., Bartoces, M., Enns, E. A., File, T. M., Finkelstein, J. A., Gerber, J. S., Hyun, D. Y., Linder, J. A., et al. (2016) · JAMA · doi:10.1001/jama.2016.4151 · Cited by 1,740 · see citing works
Self-citationInternational Consensus Statement on Allergy and Rhinology: Rhinosinusitis
Orlandi, R. R., Kingdom, T. T., Hwang, P. H., Smith, T. L., Alt, J. A., Baroody, F. M., Batra, P. S., Bernal‐Sprekelsen, M., Bhattacharyya, N., Chandra, R. K., et al. (2016) · International Forum of Allergy & Rhinology · doi:10.1002/alr.21695 · Cited by 892 · see citing works
Self-citationInternational Consensus Statement on Allergy and Rhinology: Allergic Rhinitis
Wise, S. K., Lin, S. Y., Toskala, E., Orlandi, R. R., Akdis, C. A., Alt, J. A., Azar, A., Baroody, F. M., Bachert, C., Canonica, G. W., et al. (2018) · International Forum of Allergy & Rhinology · doi:10.1002/alr.22073 · Cited by 557 · see citing works
Self-citationVelasquez, N., Thamboo, A., Habib, A. R., Huang, Z., & Nayak, J. V. (2017) · International Forum of Allergy & Rhinology · doi:10.1002/alr.21842 · Cited by 112 · see citing works
Johnson, K. M., Dumkow, L. E., Burns, K. W., Yee, M. A., & Egwuatu, N. E. (2019) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofz393 · Cited by 39 · see citing works
Otolaryngologist perceptions of AI-based sinus CT interpretation
Massey, C. J., Asokan, A., Tietbohl, C., Morris, M., & Ramakrishnan, V. R. (2023) · American Journal of Otolaryngology · doi:10.1016/j.amjoto.2023.103932 · Cited by 10 · see citing works
- Authors
- Rosenfeld, R. M., Piccirillo, J. F., Chandrasekhar, S. S., Brook, I., Ashok Kumar, K., Kramper, M., Orlandi, R. R., Palmer, J. N., Patel, Z. M., Peters, A., Walsh, S. A., & Corrigan, M. D.
- Affiliations
- SUNY Downstate Health Sciences University (US)
- Washington University in St. Louis (US)
- New York Otology New York Head and Neck Institute New York New York USA
- Georgetown University (US)
- Department of Family Medicine University of Texas Health Sciences Center at San Antonio San Antonio Texas USA
- University of Utah (US)
- Hospital of the University of Pennsylvania (US)
- Emory University (US)
- Northwestern University (US)
- Consumers United for Evidence‐Based Healthcare Davis California USA
- American Academy of Otolaryngology — Head and Neck Surgery (US)
- Corresponding author
- Rosenfeld, Richard M.
- ORCID
- Venue
- Otolaryngology–Head and Neck Surgery
- Publisher
- Wiley
- Published
- 2015-04
- Volume
- 152
- Issue
- S2
- Pages
- S1-S39
- ISSN
- 0161-6439 (ISSN-L)
- 0194-5998
- 1097-6817
- OpenAlex
- W2149116105
- Cited by
- 1,159
- References
- 301
- Citations by year
- 2026: 35 · 2025: 98 · 2024: 118 · 2023: 120 · 2022: 122 · 2021: 106 · 2020: 138 · 2019: 116 · 2018: 99 · 2017: 91 · 2016: 91 · 2015: 21
- FWCI
- 90.39
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Otolaryngology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Otorhinolaryngology › Sinusitis and nasal conditions
- Health Sciences › Medicine › Infectious Diseases › Otolaryngology and Infectious Diseases
- Life Sciences › Immunology and Microbiology › Applied Microbiology and Biotechnology › Antibiotic Use and Resistance
- Keywords
- sinusitis, acute bacterial rhinosinusitis, chronic rhinosinusitis, expectant management, antibiotic therapy, amoxicillin-clavulanic acid, nasal endoscopy, computed tomography, anterior rhinoscopy, viral upper respiratory tract infection, asthma, cystic fibrosis, immunocompromised patients, ciliary dyskinesia, patient education, quality improvement, diagnostic accuracy
- MeSH terms
- Academies and Institutes, Adult, Anti-Bacterial Agents, Humans, Otolaryngology, Rhinitis, Sinusitis, Societies, Medical, United States, Watchful Waiting
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
