The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.
Risk of Infection after Penetrating Abdominal Trauma
Abstract
To identify the risk factors for the development of postoperative septic complications in patients with intestinal perforation after abdominal trauma, and to compare the efficacies of single-drug and dual-drug prophylactic antibiotic therapy, we studied 145 patients who presented with abdominal trauma and intestinal perforation at two hospitals between July 1979 and June 1982. Logistic-regression analysis showed that a higher risk of infection (P less than 0.05) was associated with increased age, injury to the left colon necessitating colostomy, a larger number of units of blood or blood products administered at surgery, and a larger number of injured organs. The presence of shock on arrival, which was found to increase the risk of infection when this factor was analyzed individually, did not add predictive power. Patients with postoperative sepsis were hospitalized significantly longer than were patients without infection (13.8 vs. 7.7 days, P less than 0.0001). Both treatment regimens--cefoxitin given alone and clindamycin and gentamicin given together--resulted in similar infection rates, drug toxicity, duration of hospitalization, and costs.
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Cites
Baker, S. P., O’Neill, B., Haddon, W. F., & Long, W. B. (1974) · PubMed · Cited by 7,946
BAKER, S. P., OʼNEILL, B., HADDON, W., & LONG, W. B. (1974) · The Journal of Trauma: Injury, Infection, and Critical Care · doi:10.1097/00005373-197403000-00001 · Cited by 7,292
Experimental Intra-Abdominal Abscesses in Rats: Development of an Experimental Model
Weinstein, W. M., Onderdonk, A. B., Bartlett, J. G., & Gorbach, S. L. (1974) · Infection and Immunity · doi:10.1128/iai.10.6.1250-1255.1974 · Cited by 336
GREEN, J. W., & WENZEL, R. P. (1977) · Annals of Surgery · doi:10.1097/00000658-197703000-00002 · Cited by 239
Risk Factors for Infection at the Operative Site after Abdominal or Vaginal Hysterectomy
Shapiro, M., Muñoz, A., Tager, I. B., Schoenbaum, S. C., & Polk, B. F. (1982) · New England Journal of Medicine · doi:10.1056/nejm198212303072701 · Cited by 178
Enterococcal Bacteremia Clinical Implications and Determinants of Death
GARRISON, R. N., FRY, D. E., BERBERICH, S., & POLK, H. C. (1982) · Annals of Surgery · doi:10.1097/00000658-198207000-00010 · Cited by 166
Risk factors for infection at the operative site after abdominal or vaginal hysterectomy
(1983) · American Journal of Infection Control · doi:10.1016/0196-6553(83)90034-2 · Cited by 160
Simultaneous antibiotic levels in “breakthrough” gram-negative rod bacteremia
Anderson, E. T., Young, L. S., & Hewitt, W. L. (1976) · The American Journal of Medicine · doi:10.1016/0002-9343(76)90328-4 · Cited by 135
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Cited by
Guideline for Prevention of Surgical Site Infection, 1999
Mangram, A. J., Horan, T. C., Pearson, M. L., Silver, L. C., Jarvis, W. R., & The Hospital Infection Control Practices Advisory Committee (1999) · Infection Control & Hospital Epidemiology · doi:10.1086/501620 · Cited by 4,595
Clinical Prediction Rules: Applications and Methodological Standards
Wasson, J. H., Sox, H. C., Neff, R. K., & Goldman, L. (1985) · New England Journal of Medicine · doi:10.1056/nejm198509263131306 · Cited by 1,357
Metronidazole: A Therapeutic Review and Update
Freeman, C. D., Klutman, N. E., & Lamp, K. C. (1997) · Drugs · doi:10.2165/00003495-199754050-00003 · Cited by 473
Monocyte HLA-DR antigen expression characterizes clinical outcome in the trauma patient
Hershman, M. J., Cheadle, W. G., Wellhausen, S. R., Davidson, P. F., & Polk, H. C. (1990) · Journal of British Surgery · doi:10.1002/bjs.1800770225 · Cited by 348
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Metadata
- Authors
- Nichols, R. L., Smith, J. W., Klein, D. B., Trunkey, D. D., Cooper, R. H., Adinolfi, M. F., & Mills, J.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1984-10-25
- Volume
- 311
- Issue
- 17
- Pages
- 1065-1070
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2320563228
- Cited by
- 313
- References
- 10
- FWCI
- 17.02
- Type
- journal article
- Language
- en
- Open access
- closed
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- Nichols, R. L., Smith, J. W., Klein, D. B., Trunkey, D. D., Cooper, R. H., Adinolfi, M. F., & Mills, J. (1984). Risk of Infection after Penetrating Abdominal Trauma. New England Journal of Medicine. https://doi.org/10.1056/nejm198410253111701
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
