The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.
Seizure Disorders and Pregnancy
Abstract
THE objectives of treatment of the pregnant woman with epilepsy are to maintain the patient in a seizure-free state while minimizing when possible the adverse effects of the seizure disorder on the course of the pregnancy and the possible teratogenetic effects of some anticonvulsant agents on the fetus.Unless otherwise specifically indicated, the discussion in this paper will focus on primary generalized seizures (tonic–clonic or grand mal), including partial complex seizures that become generalized.Seizure Frequency in PregnancyPregnant women with epilepsy can be divided into two categories: those identified as having epilepsy before their child was conceived and in . . .
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“For example, the included studies often failed to report important treatment effect modifiers,46 such as family history of autism, ADHD and maternal IQ, severity of epilepsy making it impossible for us to explore their impact through subgroup analysis and meta-regression.”
Citations
Cites
Hanson, J. W., & Smith, D. W. (1975) · The Journal of Pediatrics · doi:10.1016/s0022-3476(75)80604-4 · Cited by 601
MATERNAL VALPROIC ACID AND CONGENITAL NEURAL TUBE DEFECTS
Robert, E., & Guibaud, P. (1982) · The Lancet · doi:10.1016/s0140-6736(82)90908-4 · Cited by 539
Hanson, J. W., Myrianthopoulos, N. C., Harvey, M. A. S., & Smith, D. W. (1976) · The Journal of Pediatrics · doi:10.1016/s0022-3476(76)80414-3 · Cited by 434
Nakane, Y., Okuma, T., Takahashi, R., Sato, Y., Wada, T., Sato, T., Fukushima, Y., Kumashiro, H., Ono, T., Takahashi, T., et al. (1980) · Epilepsia · doi:10.1111/j.1528-1157.1980.tb04320.x · Cited by 301
Diphenylhydantoin and Selected Congenital Malformations
Monson, R. R., Rosenberg, L. A., Hartz, S. C., Shapiro, S., Heinonen, O. P., & Slone, D. (1973) · New England Journal of Medicine · doi:10.1056/nejm197311152892001 · Cited by 237
Epilepsy and Pregnancy: A Report from the Oxford Record Linkage Study
Fedrick, J. (1973) · BMJ · doi:10.1136/bmj.2.5864.442 · Cited by 229
Epilepsy and Pregnancy: A Study of 153 Pregnancies in 59 Patients
Knight, A. H., & Rhind, E. G. (1975) · Epilepsia · doi:10.1111/j.1528-1157.1975.tb04726.x · Cited by 209
Change of seizure frequency in pregnant epileptic women.
Schmidt, D., Canger, R., Avanzini, G., Battino, D., Cusi, C., Beck-Mannagetta, G., Koch, S., Rating, D., & Janz, D. (1983) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.46.8.751 · Cited by 182
The fetal trimethadione syndrome
Lietman, P. S., Zackai, E. H., Mellman, W. J., Neiderer, B., & Hanson, J. W. (1975) · The Journal of Pediatrics · doi:10.1016/s0022-3476(75)80603-2 · Cited by 179
Mirkin, B. L. (1971) · The Journal of Pediatrics · doi:10.1016/s0022-3476(71)80025-2 · Cited by 161
Research works printed but not linked: 5
- Bjerkedal T, Egenaes J. Outcome of pregnancy in women with epilepsy, Norway 1967–1978: description of material. In: Janz D, Bossi L, Dam M, Helge H, Richens A, Schmidt D, eds. Epilepsy, pregnancy, and the child. New York: Raven Press, 1982:75–80.
- Egenaes J. Outcome of pregnancy in women with epilepsy — Norway, 1967 to 1978: complications during pregnancy and delivery. In: Janz D, Bossi L, Dam M, Helge H, Richens A, Schmidt D, eds. Epilepsy, pregnancy and the child. New York: Raven Press, 1982:81–5.
- Clifford, 1984, Am Fam Physician, 29, 271
- Janz D. On major malformations and minor anomalies in the offspring of parents with epilepsy: review of the literature. In: Janz D, Dam M, Bossi L, Helge H. Richens A, Schmidt D, eds. Epilepsy, pregnancy, and the child. New York: Raven Press, 1982:211–22.
- Pisciotta AV. Carbamazepine: hematological toxicity. In: Woodbury DM, Penry JK, Pippenger CE, eds. Antiepileptic drugs. New York: Raven Press, 1982:533–41.
Cited by
The Teratogenicity of Anticonvulsant Drugs
Holmes, L. B., Harvey, E. A., Coull, B. A., Huntington, K. B., Khoshbin, S., Hayes, A. M., & Ryan, L. M. (2001) · New England Journal of Medicine · doi:10.1056/nejm200104123441504 · Cited by 655
Veroniki, A. A., Rios, P., Cogo, E., Straus, S. E., Finkelstein, Y., Kealey, R., Reynen, E., Soobiah, C., Thavorn, K., Hutton, B., et al. (2017) · BMJ Open · doi:10.1136/bmjopen-2017-017248 · Cited by 222
Tomson, T., Lindbom, U., Ekqvist, B., & Sundqvist, A. (1994) · Epilepsia · doi:10.1111/j.1528-1157.1994.tb02921.x · Cited by 161
The Evaluation and Treatment of Seizures
Desforges, J. F., Scheuer, M. L., & Pedley, T. A. (1990) · New England Journal of Medicine · doi:10.1056/nejm199011223232107 · Cited by 160
Ulander, J., & Haymet, A. D. J. (2003) · Biophysical Journal · doi:10.1016/s0006-3495(03)74768-7 · Cited by 120
Metadata
- Authors
- Dalessio, D. J.
- Affiliations
- Scripps Clinic (US)
- Corresponding author
- Dalessio, Donald J.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1985-02-28
- Volume
- 312
- Issue
- 9
- Pages
- 559-563
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W1980820251
- Cited by
- 93
- References
- 23
- Citations by year
- 2017: 1 · 2015: 1
- FWCI
- 16.12
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Pharmacological Effects and Toxicity Studies
- Health Sciences › Medicine › Clinical Neurology › Epilepsy research and treatment
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Pregnancy and Medication Impact
- Keywords
- epilepsy in pregnancy, epilepsy, anticonvulsant teratogenicity, seizure frequency, tonic-clonic seizures, complex partial seizures, seizure control
- MeSH terms
- Abnormalities, Drug-Induced, Anticonvulsants, Carbamazepine, Drug Administration Schedule, Epilepsy, Female, Fetal Blood, Hemorrhage, Humans, Infant, Newborn, Monitoring, Physiologic, Phenytoin, Pregnancy, Pregnancy Complications, Trimethadione
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- Dalessio, D. J. (1985). Seizure Disorders and Pregnancy. New England Journal of Medicine. https://doi.org/10.1056/nejm198502283120906
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
