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Change of seizure frequency in pregnant epileptic women.
Open accessAbstract
The effect of pregnancy on seizure frequency was monitored prospectively in 136 pregnancies of 122 epileptic women. Pregnancy did not influence the seizure frequency in 68 pregnancies (50%). In 50 pregnancies (37%) the number of seizures increased during pregnancy or puerperium. The seizure frequency decreased in 18 pregnancies (13%). In 34 out of 50 pregnancies (68%) the increase was associated with non-compliance with the drug regimen or sleep deprivation. In seven out of 18 pregnancies (39%) improvement was related to correction of non-compliance or sleep deprivation during the pregestational nine months. Insufficiently low plasma concentrations of antiepileptic drugs were found in 47% of the women with uncontrolled epilepsy during pregnancy. The course of epilepsy during pregnancy is primarily influenced by non-compliance, sleep deprivation during pregnancy, and inadequate therapy before and during pregnancy. With good medical attention pregnancy itself seems to have only a minimal influence on the course of epilepsy.
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Citations
Cited by
Seizure Disorders and Pregnancy
Dalessio, D. J. (1985) · New England Journal of Medicine · doi:10.1056/nejm198502283120906 · Cited by 93
Metadata
- Authors
- Schmidt, D., Canger, R., Avanzini, G., Battino, D., Cusi, C., Beck-Mannagetta, G., Koch, S., Rating, D., & Janz, D.
- Venue
- Journal of Neurology, Neurosurgery & Psychiatry
- Publisher
- BMJ
- Published
- 1983-08-01
- Volume
- 46
- Issue
- 8
- Pages
- 751-755
- ISSN
- 0022-3050 (ISSN-L)
- OpenAlex
- W2036005775
- Cited by
- 182
- References
- 0
- FWCI
- 2.65
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: Change of seizure frequency in pregnant epileptic women. https://app.cochat.ai/papers/10.1136/jnnp.46.8.751
- The paper
- Schmidt, D., Canger, R., Avanzini, G., Battino, D., Cusi, C., Beck-Mannagetta, G., Koch, S., Rating, D., & Janz, D. (1983). Change of seizure frequency in pregnant epileptic women. Journal of Neurology, Neurosurgery & Psychiatry. https://doi.org/10.1136/jnnp.46.8.751
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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