The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.
Etoposide (VP-16–213): Current Status of an Active Anticancer Drug
Abstract
IN the 12 years since its introduction into clinical trials in the United States, etoposide (VP-16–213; epipodophyllotoxin; 4′-demethyl-9-[4,6–0-ethylidene-D-glucopyranoside]) has been demonstrated to be active in the treatment of several neoplastic disorders. Both etoposide and its congener teniposide (VM-26) have been the subjects of a program of detailed clinical research by the National Cancer Institute. Although data on teniposide are as yet incomplete, etoposide has been demonstrated to have cytotoxic activity against several tumors, including testicular and small-cell lung cancers, lymphoma, leukemia, and Kaposi's sarcoma associated with the acquired immunodeficiency syndrome (AIDS). In several other diseases, as we will show, its . . .
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Cites
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Etoposide (VP-16): Current Status and New Developments
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Yang, J., Liu, X., Bhalla, K., Kim, C. N., Ibrado, A. M., Cai, J., Peng, T.-I., Jones, D. P., & Wang, X. (1997) · Science · doi:10.1126/science.275.5303.1129 · Cited by 4,911
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Nepali, K., Sharma, S., Sharma, M., Bedi, P. M. S., & Dhar, K. L. (2014) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2014.03.018 · Cited by 435
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Metadata
- Authors
- O'Dwyer, P. J., Leyland-Jones, B., Alonso, M. T., Marsoni, S., & Wittes, R. E.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1985-03-14
- Volume
- 312
- Issue
- 11
- Pages
- 692-700
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2040785900
- Cited by
- 358
- References
- 19
- FWCI
- 8.46
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Etoposide (VP-16–213): Current Status of an Active Anticancer Drug. https://app.cochat.ai/papers/10.1056/nejm198503143121106
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- O'Dwyer, P. J., Leyland-Jones, B., Alonso, M. T., Marsoni, S., & Wittes, R. E. (1985). Etoposide (VP-16–213): Current Status of an Active Anticancer Drug. New England Journal of Medicine. https://doi.org/10.1056/nejm198503143121106
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
