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Potential Epidemic of Creutzfeldt–Jakob Disease from Human Growth Hormone Therapy
Abstract
A DECADE after the demonstration that Creutzfeldt—Jakob disease could be accidentally transmitted from one person to another during brain or eye surgery,1 , 2 iatrogenic Creutzfeldt—Jakob disease has reappeared as a result of earlier therapy with human growth hormone, with the ominous possibility of a burgeoning epidemic.Within just a few months, three young adults in the United States have died from the disease, confirmed neuropathologically in two patients and clinically detected but unconfirmed in one3; an additional neuropathologically confirmed case has been identified in Great Britain.4 Salient data on these four cases are summarized in Table 1. (The details of both . . .
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Metadata
- Authors
- Brown, P., Gajdusek, D. C., Gibbs, C. J., & Asher, D. M.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1985-09-19
- Volume
- 313
- Issue
- 12
- Pages
- 728-731
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W1964187029
- Cited by
- 231
- References
- 0
- FWCI
- 10.21
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Potential Epidemic of Creutzfeldt–Jakob Disease from Human Growth Hormone Therapy. https://app.cochat.ai/papers/10.1056/nejm198509193131205
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- Brown, P., Gajdusek, D. C., Gibbs, C. J., & Asher, D. M. (1985). Potential Epidemic of Creutzfeldt–Jakob Disease from Human Growth Hormone Therapy. New England Journal of Medicine. https://doi.org/10.1056/nejm198509193131205
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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