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Hypertrophic Cardiomyopathy
Abstract
(Second of Two Parts)Interrelation between Pathophysiologic Mechanisms and Disease ManifestationsSymptomsThe chief symptoms of hypertrophic cardiomyopathy are exertional angina, dyspnea, fatigue, and impaired consciousness (transient spells of lightheadedness, near-syncope, and syncope). However, a direct, one-to-one correlation between a particular symptom and a single pathophysiologic mechanism does not always exist. For example, in a population of patients with hypertrophic cardiomyopathy, a general relation exists between the severity of symptoms and the magnitude of left ventricular hypertrophy19; however, this correlation is not absolute, and some patients with mild and localized hypertrophy may have severe symptoms,36 whereas other patients with . . .
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Citations
Cited by
(2004) · European Heart Journal · doi:10.1016/j.ehj.2004.06.002 · Cited by 557
Rosenzweig, A., Watkins, H., Hwang, D.-S., Miri, M., McKenna, W., Traill, T. A., Seidman, J. G., & Seidman, C. E. (1991) · New England Journal of Medicine · doi:10.1056/nejm199112193252501 · Cited by 181
Schaff, H. V., Brown, M. L., Dearani, J. A., Abel, M. D., Ommen, S. R., Sorajja, P., Tajik, A. J., & Nishimura, R. A. (2010) · The Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2009.07.079 · Cited by 91
Transgenic rabbit model for human troponin I-based hypertrophic cardiomyopathy
Sanbe, A., James, J., Tuzcu, V., Nas, S., Martin, L., Gulick, J., Osinska, H., Sakthivel, S., Klevitsky, R., Ginsburg, K. S., et al. (2005) · Circulation · doi:10.1161/01.cir.0000164234.24957.75 · Cited by 74
Kyriakidis, M., Triposkiadis, F., Dernellis, J., Androulakis, A. E., Mellas, P., Kelepeshis, G. A., & Gialafos, J. E. (1998) · Circulation · doi:10.1161/01.cir.97.14.1342 · Cited by 42
Metadata
- Authors
- Maron, B. J., Bonow, R. O., Cannon, R. O., Leon, M. B., & Epstein, S. E.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1987-04-02
- Volume
- 316
- Issue
- 14
- Pages
- 844-852
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W4292921485
- Cited by
- 370
- References
- 0
- FWCI
- 13.53
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Hypertrophic Cardiomyopathy. https://app.cochat.ai/papers/10.1056/nejm198704023161405
- The paper
- Maron, B. J., Bonow, R. O., Cannon, R. O., Leon, M. B., & Epstein, S. E. (1987). Hypertrophic Cardiomyopathy. New England Journal of Medicine. https://doi.org/10.1056/nejm198704023161405
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.