Transgenic rabbit model for human troponin I-based hypertrophic cardiomyopathy

Cardiac excitation–contraction coupling

Bers, D., & Despa, S. (2002) · Nature · doi:10.1038/415198a · Cited by 4,927 · see citing works

Hypertrophic Cardiomyopathy

Hypertensive, Y., & Chin, K. (1982) · Springer eBooks · doi:10.1007/978-3-642-68282-7 · Cited by 1,757 · see citing works

Hypertrophic Cardiomyopathy

Maron, B. J., Bonow, R. O., Cannon, R. O., Leon, M. B., & Epstein, S. E. (1987) · New England Journal of Medicine · doi:10.1056/nejm198703263161305 · Cited by 896 · see citing works

Relaxation in rabbit and rat cardiac cells: species-dependent differences in cellular mechanisms

Bassani, J. W., Bassani, R. A., & Bers, D. M. (1994) · The Journal of Physiology · doi:10.1113/jphysiol.1994.sp020130 · Cited by 662 · see citing works

Mutations in the cardiac troponin I gene associated with hypertrophic cardiomyopathy

Kimura, A., Harada, H., Park, J.-E., Nishi, H., Satoh, M., Takahashi, M., Hiroi, S., Sasaoka, T., Ohbuchi, N., Nakamura, T., et al. (1997) · Nature Genetics · doi:10.1038/ng0897-379 · Cited by 576 · see citing works

Dephosphorylation and Intracellular Redistribution of Ventricular Connexin43 During Electrical Uncoupling Induced by Ischemia

Beardslee, M. A., Lerner, D. L., Tadros, P. N., Laing, J. G., Beyer, E. C., Yamada, K. A., Kléber, A. G., Schuessler, R. B., & Saffitz, J. E. (2000) · Circulation Research · doi:10.1161/01.res.87.8.656 · Cited by 507 · see citing works

The Molecular Genetic Basis for Hypertrophic Cardiomyopathy

Marian, A. J., & Roberts, R. (2001) · Journal of Molecular and Cellular Cardiology · doi:10.1006/jmcc.2001.1340 · Cited by 436 · see citing works

Hypertrophic Cardiomyopathy

Maron, B. J., Bonow, R. O., Cannon, R. O., Leon, M. B., & Epstein, S. E. (1987) · New England Journal of Medicine · doi:10.1056/nejm198704023161405 · Cited by 370 · see citing works

Simvastatin Induces Regression of Cardiac Hypertrophy and Fibrosis and Improves Cardiac Function in a Transgenic Rabbit Model of Human Hypertrophic Cardiomyopathy

Patel, R., Nagueh, S. F., Tsybouleva, N., Abdellatif, M., Lutucuta, S., Kopelen, H. A., Quiñones, M. A., Zoghbi, W. A., Entman, M. L., Roberts, R., et al. (2001) · Circulation · doi:10.1161/hc2801.094031 · Cited by 353 · see citing works

Gap junction alterations in human cardiac disease

Severs, N. J. (2004) · Cardiovascular Research · doi:10.1016/j.cardiores.2003.12.007 · Cited by 301 · see citing works

Human connexin43 gap junction channels. Regulation of unitary conductances by phosphorylation.

Moreno, A. P., Sáez, J. C., Fishman, G. I., & Spray, D. C. (1994) · Circulation Research · doi:10.1161/01.res.74.6.1050 · Cited by 256 · see citing works

Reengineering Inducible Cardiac-Specific Transgenesis With an Attenuated Myosin Heavy Chain Promoter

Sanbe, A., Gulick, J. M., Hanks, M. C., Liang, Q., Osińska, H. E., & Robbins, J. M. (2003) · Circulation Research · doi:10.1161/01.res.0000065442.64694.9f · Cited by 249 · see citing works

A study of the factors responsible for rate‐dependent shortening of the action potential in mammalian ventricular muscle.

Boyett, M. R., & Jewell, B. R. (1978) · The Journal of Physiology · doi:10.1113/jphysiol.1978.sp012576 · Cited by 220 · see citing works

Modulation of excitation–contraction coupling by isoproterenol in cardiomyocytes with controlled SR Ca2+ load and Ca2+ current trigger

Ginsburg, K. S., & Bers, D. M. (2004) · The Journal of Physiology · doi:10.1113/jphysiol.2003.055384 · Cited by 184 · see citing works

Phenotypic diversity in hypertrophic cardiomyopathy

Arad, M. (2002) · Human Molecular Genetics · doi:10.1093/hmg/11.20.2499 · Cited by 183 · see citing works

A transgenic rabbit model for human hypertrophic cardiomyopathy

Marian, A. J., Wu, Y., Lim, D.-S., McCluggage, M., Youker, K., Yu, Q.-T., Brugada, R., DeMayo, F., Quinones, M., & Roberts, R. (1999) · Journal of Clinical Investigation · doi:10.1172/jci7956 · Cited by 181 · see citing works

Altered Regulatory Properties of Human Cardiac Troponin I Mutants That Cause Hypertrophic Cardiomyopathy

Elliott, K., Watkins, H. C., & Redwood, C. S. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m002502200 · Cited by 153 · see citing works

Transgenic Modeling of a Cardiac Troponin I Mutation Linked to Familial Hypertrophic Cardiomyopathy

James, J. F., Zhang, Y., Osińska, H. E., Sanbe, A., Klevitsky, R., Hewett, T. E., & Robbins, J. M. (2000) · Circulation Research · doi:10.1161/01.res.87.9.805 · Cited by 149 · see citing works

New Insights into Myocardial Arrhythmogenesis: Distribution of Gap-Junctional Coupling in Normal, Ischaemic and Hypertrophied Human Hearts

Peters, N. S. (1996) · Clinical Science · doi:10.1042/cs0900447 · Cited by 141 · see citing works

Abnormal Cardiac Structure and Function in Mice Expressing Nonphosphorylatable Cardiac Regulatory Myosin Light Chain 2

Sanbe, A., Fewell, J. G., Gulick, J. M., Osińska, H. E., Lorenz, J. N., Hall, D. G., Murray, L. A., Kimball, T. R., Witt, S. A., & Robbins, J. M. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.30.21085 · Cited by 123 · see citing works

Change in synthesis rates of alpha- and beta-myosin heavy chains in rabbit heart after treatment with thyroid hormone.

Everett, A. W., Clark, W. A., Chizzonite, R., & Zak, R. (1983) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)32942-9 · Cited by 97 · see citing works

Cardiac Na/Ca Exchange Function in Rabbit, Mouse and Man: What's the Difference?

Bers, D. M. (2002) · Journal of Molecular and Cellular Cardiology · doi:10.1006/jmcc.2002.1530 · Cited by 94 · see citing works

Functional Consequences of the Mutations in Human Cardiac Troponin I Gene Found in Familial Hypertrophic Cardiomyopathy

Takahashi‐Yanaga, F., Morimoto, S., Harada, K., Minakami, R., Shiraishi, F., Ohta, M., Lu, Q.-W., Sasaguri, T., & Ohtsuki, I. (2001) · Journal of Molecular and Cellular Cardiology · doi:10.1006/jmcc.2001.1473 · Cited by 92 · see citing works

Functional significance of cardiac myosin essential light chain isoform switching in transgenic mice.

Fewell, J. G., Hewett, T. E., Sanbe, A., Klevitsky, R., Hayes, E., Warshaw, D. M., Maughan, D. W., & Robbins, J. M. (1998) · Journal of Clinical Investigation · doi:10.1172/jci2825 · Cited by 88 · see citing works

Investigation of a Truncated Cardiac Troponin T That Causes Familial Hypertrophic Cardiomyopathy

Redwood, C. S., Lohmann, K., Bing, W., Esposito, G. M., Elliott, K., Abdulrazzak, H., Knott, A., Purcell, I. F., Marston, S. B., & Watkins, H. C. (2000) · Circulation Research · doi:10.1161/01.res.86.11.1146 · Cited by 75 · see citing works

Invited Review: Pathophysiology of cardiac muscle contraction and relaxation as a result of alterations in thin filament regulation

Hernandez, O. M., Housmans, P. R., & Potter, J. D. (2001) · Journal of Applied Physiology · doi:10.1152/jappl.2001.90.3.1125 · Cited by 73 · see citing works

Essential role of troponin I in the positive inotropic response to isoprenaline in mouse hearts contracting auxotonically

Layland, J., Grieve, D., Cave, A. C., Sparks, E., Solaro, R. J., & Shah, A. M. (2004) · The Journal of Physiology · doi:10.1113/jphysiol.2004.061176 · Cited by 66 · see citing works

Myofilament Calcium Sensitivity and Cardiac Disease

Westfall, M. V., Borton, A. R., Albayya, F. P., & Metzger, J. M. (2002) · Circulation Research · doi:10.1161/01.res.0000034710.46739.c0 · Cited by 57 · see citing works

QT-interval variability in hypertrophic cardiomyopathy patients with cardiac arrest

Miorelli, M., Buja, G., Melacini, P., Fasoli, G., & Nava, A. K. (1994) · International Journal of Cardiology · doi:10.1016/0167-5273(94)90267-4 · Cited by 52 · see citing works

Cardiac muscle cell interaction: from microanatomy to the molecular make-up of the gap junction.

Severs, N. J. (1995) · PubMed · Cited by 44 · see citing works

Anisomycin downregulates gap-junctional intercellular communication via the p38 MAP-kinase pathway

Ogawa, T., Hayashi, T., Kyoizumi, S., Kusunoki, Y., Nakachi, K., MacPhee, D. G., Trosko, J. E., Kataoka, K., & Yorioka, N. (2004) · Journal of Cell Science · doi:10.1242/jcs.01056 · Cited by 38 · see citing works

Deletion in the Cardiac Troponin I Gene in a Family From Northern Sweden with Hypertrophic Cardiomyopathy

Mörner, S., Richard, P., Kazzam, E. E., Hainque, B., Schwartz, K., & Waldenström, A. P. (2000) · Journal of Molecular and Cellular Cardiology · doi:10.1006/jmcc.1999.1099 · Cited by 37 · see citing works

Variability in the ratio of mutant to wildtype myosin heavy chain present in the soleus muscle of patients with familial hypertrophic cardiomyopathy. A new approach for the quantification of mutant to wildtype protein

Nier, V., Schultz, I., Brenner, B., Forssmann, W., & Raida, M. (1999) · FEBS Letters · doi:10.1016/s0014-5793(99)01433-7 · Cited by 35 · see citing works

Myosin light chain replacement in the heart

Sanbe, A., Gulick, J. M., Hayes, E. S., Warshaw, D. M., Osińska, H. E., Chan, C.-B., Klevitsky, R., & Robbins, J. M. (2000) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.2000.279.3.h1355 · Cited by 34 · see citing works

Fibroblast growth factor-2 stimulates embryonic cardiac mesenchymal cell proliferation

Choy, M., Oltjen, S. L., Otani, Y. S., Armstrong, M. T., & Armstrong, P. B. (1996) · Developmental Dynamics · doi:10.1002/(sici)1097-0177(199606)206:2 · Cited by 24 · see citing works

Genetic Manipulation of the Rabbit Heart via Transgenesis

James, J. F., Sanbe, A., Yager, K. L., Martin, L. A., Klevitsky, R., & Robbins, J. M. (2000) · Circulation · doi:10.1161/01.cir.101.14.1715 · Cited by 23 · see citing works

Characterization and Quantitation of Extracellular Collagen Matrix in Myocardium of Pigs with Spontaneously Occurring Hypertrophic Cardiomyopathy

Chiu, Y.-T., Liu, S., Liu, M., Chen, S. P., Lin, Y. H., Mao, S. J. T., & Chu, R. (1999) · Cardiovascular Pathology · doi:10.1016/s1054-8807(98)00031-3 · Cited by 23 · see citing works

Temporal Complexity of Repolarization and Mortality in Patients with Implantable Cardioverter Defibrillators

Perkiömäki, J. S., Couderc, J., Daubert, J. P., & Zaręba, W. (2003) · Pacing and Clinical Electrophysiology · doi:10.1046/j.1460-9592.2003.00298.x · Cited by 20 · see citing works

Small and large animal models in cardiac contraction research: advantages and disadvantages

Milani-Nejad, N., & Janssen, P. M. L. (2014) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2013.10.007 · Cited by 484 · see citing works

Functional consequences of abnormal Cx43 expression in the heart

Fontes, M. S. C., van Veen, T. A. B., de Bakker, J. M. T., & van Rijen, H. V. M. (2011) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2011.07.039 · Cited by 189 · see citing works

Lost in Transgenesis

Davis, J., Maillet, M., Miano, J. M., & Molkentin, J. D. (2012) · Circulation Research · doi:10.1161/circresaha.111.262717 · Cited by 113 · see citing works

Biology and Diseases of Rabbits

Nowland, M. H., Brammer, D. W., García, A., & Rush, H. G. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-409527-4.00010-9 · Cited by 103 · see citing works

Protective Effect of Geranylgeranylacetone via Enhancement of HSPB8 Induction in Desmin-Related Cardiomyopathy

Sanbe, A., Daicho, T., Mizutani, R., Endo, T., Miyauchi, N., Yamauchi, J., Tanonaka, K., Glabe, C. G., & Tanoue, A. (2009) · PLoS ONE · doi:10.1371/journal.pone.0005351 · Cited by 96 · see citing works

Increased myofilament Ca2+-sensitivity and arrhythmia susceptibility

Huke, S., & Knollmann, B. C. (2010) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2010.01.011 · Cited by 86 · see citing works

Severe Heart Failure and Early Mortality in a Double-Mutation Mouse Model of Familial Hypertrophic Cardiomyopathy

Tsoutsman, T., Kelly, M., Ng, D. C. H., Tan, J. K., Tu, E., Lam, L., Bogoyevitch, M. A., Seidman, C. E., Seidman, J. G., & Semsarian, C. (2008) · Circulation · doi:10.1161/circulationaha.107.755777 · Cited by 80 · see citing works

Forced Expression of α-Myosin Heavy Chain in the Rabbit Ventricle Results in Cardioprotection Under Cardiomyopathic Conditions

James, J., Martin, L., Krenz, M., Quatman, C., Jones, F., Klevitsky, R., Gulick, J., & Robbins, J. (2005) · Circulation · doi:10.1161/01.cir.0000164233.09448.b1 · Cited by 77 · see citing works

MR tagging demonstrates quantitative differences in regional ventricular wall motion in mice, rats, and men

Liu, W., Ashford, M. W., Chen, J., Watkins, M. P., Williams, T. A., Wickline, S. A., & Yu, X. (2006) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.01016.2005 · Cited by 74 · see citing works

Abnormalities in sodium current and calcium homoeostasis as drivers of arrhythmogenesis in hypertrophic cardiomyopathy

Coppini, R., Santini, L., Olivotto, I., Ackerman, M. J., & Cerbai, E. (2020) · Cardiovascular Research · doi:10.1093/cvr/cvaa124 · Cited by 72 · see citing works

Impaired relaxation is the main manifestation in transgenic mice expressing a restrictive cardiomyopathy mutation, R193H, in cardiac TnI

Du, J., Liu, J., Feng, H., Hossain, M., Gobara, N., Zhang, C., Li, Y., Jean-Charles, P.-Y., Jin, J., & Huang, X.-P. (2008) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.91506.2007 · Cited by 73 · see citing works

On the emerging role of rabbit as human disease model and the instrumental role of novel transgenic tools

Duranthon, V., Beaujean, N., Brunner, M. P., Odening, K. E., Santos, A. N., Kacskovıcs, I., Hiripi, L., Weinstein, E. J., & Bösze, Z. (2012) · Transgenic Research · doi:10.1007/s11248-012-9599-x · Cited by 67 · see citing works

Application of rabbits in biomedical research: a review.

Bösze, Z., & Houdebine, L. (2010) · World Rabbit Science · doi:10.4995/wrs.2006.712 · Cited by 66 · see citing works

Inherited cardiomyopathies caused by troponin mutations.

Lu, Q., Wu, X. Y., & Morimoto, S. (2013) · Europe PMC (PubMed Central) · doi:10.3969/j.issn.1671-5411.2013.01.014 · Cited by 63 · see citing works

Functional Consequences of the Human Cardiac Troponin I Hypertrophic Cardiomyopathy Mutation R145G in Transgenic Mice

Wen, Y., Pinto, J. R., Gomes, A. V., Xu, Y., Wang, Y., Wang, Y., Potter, J. D., & Kerrick, W. G. L. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m801661200 · Cited by 60 · see citing works

Designing Heart Performance by Gene Transfer

Davis, J., Westfall, M. V., Townsend, D., Blankinship, M. J., Herron, T. J., Guerrero‐Serna, G., Wang, W., Devaney, E. J., & Metzger, J. M. (2008) · Physiological Reviews · doi:10.1152/physrev.00039.2007 · Cited by 58 · see citing works

ESC working group on cardiac cellular electrophysiology position paper: relevance, opportunities, and limitations of experimental models for cardiac electrophysiology research

Odening, K. E., Gomez, A. M., Dobrev, D., Fabritz, L., Heinzel, F. R., Mangoni, M. E., Molina, C. E., Sacconi, L., Smith, G. L., Štengl, M., et al. (2021) · EP Europace · doi:10.1093/europace/euab142 · Cited by 58 · see citing works

Enhanced Transmural Fiber Rotation and Connexin 43 Heterogeneity Are Associated With an Increased Upper Limit of Vulnerability in a Transgenic Rabbit Model of Human Hypertrophic Cardiomyopathy

Ripplinger, C. M., Li, W., Hadley, J., Chen, J., Rothenberg, F. G., Lombardi, R., Wickline, S. A., Marian, A. J., & Efimov, I. R. (2007) · Circulation Research · doi:10.1161/circresaha.107.161240 · Cited by 55 · see citing works

Rabbit models of heart disease

Pogwizd, S. M., & Bers, D. M. (2008) · Drug Discovery Today Disease Models · doi:10.1016/j.ddmod.2009.02.001 · Cited by 53 · see citing works

Animal and in silico models for the study of sarcomeric cardiomyopathies

Duncker, D. J., Bakkers, J., Brundel, B. J. J. M., Robbins, J. M., Tardiff, J. C., & Carrier, L. (2015) · Cardiovascular Research · doi:10.1093/cvr/cvv006 · Cited by 54 · see citing works

A point mutation (R192H) in the C-terminus of human cardiac troponin I causes diastolic dysfunction in transgenic mice

Du, J., Zhang, C., Liu, J., Sidky, C., & Huang, X. P. (2006) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2006.08.018 · Cited by 53 · see citing works

Oxidative Stress and Myocardial Gene Alterations Associated with Doxorubicin-Induced Cardiotoxicity in Rats Persist for 2 Months after Treatment Cessation

Richard, C., Ghibu, S., Delemasure, S., Guilland, J.-C., Rosiers, C. D., Zeller, M., Cottin, Y., Rochette, L., & Vergely, C. (2011) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.111.185892 · Cited by 51 · see citing works

Genetic basis and molecular biology of cardiac arrhythmias in cardiomyopathies

Marian, A. J., Asatryan, B., & Wehrens, X. H. T. (2020) · Cardiovascular Research · doi:10.1093/cvr/cvaa116 · Cited by 47 · see citing works

Troponin and cardiomyopathy

Chang, A. N., Parvatiyar, M. S., & Potter, J. D. (2008) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2007.12.081 · Cited by 46 · see citing works

In Vivo Analysis of Troponin C Knock-In (A8V) Mice

Martins, A. S., Parvatiyar, M. S., Feng, H., Bos, J. M., Gonzalez-Martinez, D., Vukmirovic, M., Turna, R. S., Sanchez‐Gonzalez, M. A., Badger, C.-D., Zorio, D. A. R., et al. (2015) · Circulation Cardiovascular Genetics · doi:10.1161/circgenetics.114.000957 · Cited by 44 · see citing works

A quantitative comparison of regional myocardial motion in mice, rabbits and humans using in-vivo phase contrast CMR

Jung, B., Odening, K. E., Dall'Armellina, E., Föll, D., Menza, M., Markl, M., & Schneider, J. E. (2012) · Journal of Cardiovascular Magnetic Resonance · doi:10.1186/1532-429x-14-87 · Cited by 44 · see citing works

Allele and species dependent contractile defects by restrictive and hypertrophic cardiomyopathy-linked troponin I mutants

Davis, J., Wen, H., Edwards, T., & Metzger, J. M. (2008) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2008.02.274 · Cited by 43 · see citing works

Comparison of Glycerol, Lactamide, Acetamide and Dimethylsulfoxide as Cryoprotectants of Japanese White Rabbit Spermatozoa

Kashiwazaki, N., OKUDA, Y., Seita, Y., Hisamatsu, S., Sonoki, S., Shino, M., Masaoka, T., & Inomata, T. (2006) · Journal of Reproduction and Development · doi:10.1262/jrd.18008 · Cited by 41 · see citing works

Molecular insights from a novel cardiac troponin I mouse model of familial hypertrophic cardiomyopathy

Tsoutsman, T., Chung, J., Doolan, A., Nguyen, L., Williams, I. A., Tu, E., Lam, L., Bailey, C. G., Rasko, J. E. J., Allen, D. G., et al. (2006) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2006.07.016 · Cited by 37 · see citing works

Hypertrophic cardiomyopathy R403Q mutation in rabbit β-myosin reduces contractile function at the molecular and myofibrillar levels

Lowey, S., Bretton, V., Joel, P. B., Trybus, K. M., Gulick, J. M., Robbins, J. M., Kalganov, A., Cornachione, A. S., & Rassier, D. E. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1802967115 · Cited by 35 · see citing works

Progressive troponin I loss impairs cardiac relaxation and causes heart failure in mice

Liu, J., Du, J., Zhang, C., Walker, J. W., & Huang, X. (2007) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.01379.2006 · Cited by 34 · see citing works

On Mice, Rabbits, and Human Heart Failure

Marian, A. J. (2005) · Circulation · doi:10.1161/01.cir.0000167559.13502.9a · Cited by 33 · see citing works

Phospholamban overexpression in transgenic rabbits

Pattison, J. S., Waggoner, J. R., James, J. F., Martin, L. J., Gulick, J. M., Osińska, H. E., Klevitsky, R., Kranias, E. G., & Robbins, J. M. (2007) · Transgenic Research · doi:10.1007/s11248-007-9139-2 · Cited by 31 · see citing works

Transgenic rabbit models for cardiac disease research

Hornyik, T., Rieder, M., Castiglione, A., Major, P., Baczkó, I., Brunner, M. P., Koren, G., & Odening, K. E. (2021) · British Journal of Pharmacology · doi:10.1111/bph.15484 · Cited by 31 · see citing works

Passive ventricular remodeling in cardiac disease: focus on heterogeneity

Kessler, E. L., Boulaksil, M., van Rijen, H. V. M., Vos, M. A., & van Veen, T. A. B. (2014) · Frontiers in Physiology · doi:10.3389/fphys.2014.00482 · Cited by 29 · see citing works

Role of the acidic N′ region of cardiac troponin I in regulating myocardial function

Sadayappan, S., Finley, N. L., Howarth, J. W., Osińska, H. E., Klevitsky, R., Lorenz, J. N., Rosevear, P. R., & Robbing, J. (2007) · The FASEB Journal · doi:10.1096/fj.07-9458com · Cited by 27 · see citing works

A One Health Approach to Hypertrophic Cardiomyopathy.

Ueda, Y., & Stern, J. A. (2017) · Europe PMC (PubMed Central) · Cited by 26 · see citing works

Diastolic dysfunction and thin filament dysregulation resulting from excitation–contraction uncoupling in a mouse model of restrictive cardiomyopathy

Davis, J., Yasuda, S., Palpant, N. J., Martindale, J. J., Stevenson, T. K., Converso, K. L., & Metzger, J. M. (2012) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2012.05.018 · Cited by 25 · see citing works

Modelling genetic diseases for drug development: Hypertrophic cardiomyopathy

Santini, L., Palandri, C., Nediani, C., Cerbai, E., & Coppini, R. (2020) · Pharmacological Research · doi:10.1016/j.phrs.2020.105176 · Cited by 24 · see citing works

Ultrastructural changes, increased oxidative stress, inflammation, and altered cardiac hypertrophic gene expressions in heart tissues of rats exposed to incense smoke

Al-Attas, O. S., Hussain, T., Ahmed, M., Al‐Daghri, N. M., Mohammed, A. A., Rosas, E. D., Gambhir, D., & Sumague, T. S. (2015) · Environmental Science and Pollution Research · doi:10.1007/s11356-015-4212-5 · Cited by 24 · see citing works

The potential impact of new generation transgenic methods on creating rabbit models of cardiac diseases

Bösze, Z., Major, P., Baczkó, I., Odening, K. E., Bodrogi, L., Hiripi, L., & Varró, A. (2016) · Progress in Biophysics and Molecular Biology · doi:10.1016/j.pbiomolbio.2016.05.007 · Cited by 21 · see citing works

Upregulation of Myocardial and Vascular Phosphodiesterase 9A in A Model of Atherosclerotic Cardiovascular Disease

Priksz, D., Bombicz, M., Varga, B., Kurucz, A., Gesztelyi, R., Balla, J., Tóth, A., Papp, Z., Szilvássy, Z., & Juhász, B. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19102882 · Cited by 17 · see citing works

Transgenic Rabbit Models: Now and the Future

Matsuhisa, F., Kitajima, S., Nishijima, K., Akiyoshi, T., Morimoto, M., & Fan, J. (2020) · Applied Sciences · doi:10.3390/app10217416 · Cited by 16 · see citing works

Phenotypic variation and targeted therapy of hypertrophic cardiomyopathy using genetic animal models

Gannon, M. P., & Link, M. S. (2019) · Trends in Cardiovascular Medicine · doi:10.1016/j.tcm.2019.11.009 · Cited by 13 · see citing works

Role of Animal Models in HCM Research

Shephard, R., & Semsarian, C. (2009) · Journal of Cardiovascular Translational Research · doi:10.1007/s12265-009-9120-y · Cited by 14 · see citing works

Experimental Models of Hypertrophic Cardiomyopathy

van den Dolder, F. W., Dinani, R., Warnaar, V. A. J., Vuckovic, S., Passadouro, A. S., Nassar, A. A., Ramsaroep, A. X., Burchell, G. B., Schoonmade, L. J., van der Velden, J., et al. (2025) · JACC Basic to Translational Science · doi:10.1016/j.jacbts.2024.10.017 · Cited by 14 · see citing works

Effects of exercise on heart rate variability by time-domain, frequency-domain and non-linear analyses in equine athletes

Li, K. H. C., Lai, R. W. C., Du, Y., Ly, V., Li, D. C. Y., Lam, M. H. S., Roever, L., Fitzgerald-Smith, S., Li, G., Liu, T., et al. (2019) · F1000Research · doi:10.12688/f1000research.17997.1 · Cited by 11 · see citing works

Follow the white rabbit

Odening, K. E., & Kohl, P. K. (2016) · Progress in Biophysics and Molecular Biology · doi:10.1016/j.pbiomolbio.2016.06.002 · Cited by 9 · see citing works

Genetically modified rabbit models for cardiovascular medicine

Hou, Y., Zhang, X., Sun, X., Qin, Q., Chen, D., Jia, M., & Chen, Y. (2022) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2022.174890 · Cited by 8 · see citing works

Animal Models of Cardiomyopathies

Purevjav, E. (2019) · IntechOpen eBooks · doi:10.5772/intechopen.89033 · Cited by 8 · see citing works

Quantification of Beat-To-Beat Variability of Action Potential Durations in Langendorff-Perfused Mouse Hearts

Tse, G., Du, Y., Hao, G., Li, K. H. C., Chan, F. Y. W., Liu, T., Li, G., Bazoukis, G., Letsas, Κ. P., Wu, W. K. K., et al. (2018) · Frontiers in Physiology · doi:10.3389/fphys.2018.01578 · Cited by 8 · see citing works

Heartbeat dynamics in adrenergic blocker treated conscious beagle dogs

Li, D., Chiang, A. Y., Clawson, C. A., Main, B. W., & Leishman, D. J. (2008) · Journal of Pharmacological and Toxicological Methods · doi:10.1016/j.vascn.2008.05.005 · Cited by 7 · see citing works

CMV promoter is inadequate for expression of mutant human RyR2 in transgenic rabbits

Wakula, P., Bisping, E. H., Kockskämper, J., Post, H., Brauer, S., Deuter, M., Oehlmann, R., Besenfelder, U., Lai, F. A., Brem, G., et al. (2010) · Journal of Pharmacological and Toxicological Methods · doi:10.1016/j.vascn.2010.09.007 · Cited by 7 · see citing works

Mechanism of Ion Channel Impairment in the Occurrence of Arrhythmia in Patients with Hypertrophic Cardiomyopathy

Zhang, K., Wang, S., Li, X., Cui, H., & Lai, Y. (2023) · Cardiology in Review · doi:10.1097/crd.0000000000000612 · Cited by 5 · see citing works

In vivomodels of cardiac diseases: application to drug development and screening

Rokutan, H., Anker, S. D., & Springer, J. (2009) · Expert Opinion on Drug Discovery · doi:10.1517/17460440903460299 · Cited by 3 · see citing works

The Applications of Transgenic Rabbits in Agriculture and Biomedicine

Zabetian, M., Tahmooresp, M., & Hosseini, K. (2011) · Journal of Animal and Veterinary Advances · doi:10.3923/javaa.2011.780.790 · Cited by 3 · see citing works

General topic: applications of transgenic rabbits in biomedical research - based on literature search

Zhao, S., Wei, K., Yu, Q., Li, Y., Cheng, F., Wang, Y., Yang, P., Fan, J., & Liu, E. (2010) · World Rabbit Science · doi:10.4995/wrs.2010.7279 · Cited by 3 · see citing works

Molecular Pathways and Animal Models of Cardiomyopathies

Orgil, B., & Purevjav, E. (2024) · Advances in experimental medicine and biology · doi:10.1007/978-3-031-44087-8_64 · Cited by 3 · see citing works

Proliferative Potential of Cardiomyocytes in Hypertrophic Cardiomyopathy: Correlation with Myocardial Remodeling

Sukhacheva, T. V., Chudinovskikh, Y. A., Еремеева, М. В., Serov, R. A., & Bockeria, L. A. (2016) · Bulletin of Experimental Biology and Medicine · doi:10.1007/s10517-016-3566-0 · Cited by 3 · see citing works

Animal Models and Methods of Myocardial Infarction Induction and the Role of Tissue Engineering in the Regeneration of Damaged Myocardium

Fakhr, M. J., Dezfouli, M. R. M., & Chaleshtori, S. S. (2022) · Current Stem Cell Research & Therapy · doi:10.2174/1574888x17666221011085745 · Cited by 2 · see citing works

Familial Hypertrophic Cardiomyopathy-Related Troponin Mutations and Sudden Cardiac Death

Dewar, L. J., Liang, B., Li, Y., Sanatani, S., & Glen, F. (2012) · InTech eBooks · doi:10.5772/28144 · Cited by 1 · see citing works

Cardiomyopathies in Animals

Sasaki, K., Mutoh, T., Shirota, K., & Kawashima, R. (2017) · InTech eBooks · doi:10.5772/65060 · Cited by 1 · see citing works

Transgenic Animal Models of Cardiac Channelopathies: Benefits and Limitations

Odening, K. E., & Ziupa, D. (2018) · Cardiac and vascular biology · doi:10.1007/978-3-319-77812-9_15 · Cited by 1 · see citing works

Cardiovascular Activity

Vogel, H. G. (2007) · Springer eBooks · doi:10.1007/978-3-540-70995-4_2 · Cited by 1 · see citing works

Hypertrophic Cardiomyopathy

Marian, A. J. (2007) · Wiley eBooks · doi:10.1002/9780470691977.ch3 · Cited by 1 · see citing works

The Physiological Consequences of Hypertrophic Cardiomyopathy (HCM) and Restrictive Cardiomyopathy (RCM) Related Mutations in Human Cardiac Troponin I

Wen, Y. (2008)

Effect of beta-blockers on the heart rhythm complexity in children

Ugur, A., Nas, S., & Tuzcu, V. (2011) · Conference proceedings/Conference proceedings - IEEE International Conference on Systems, Man, and Cybernetics · doi:10.1109/icsmc.2011.6083825

Ανταπόκριση στη θεραπεία με αντιβιοτικά τελευταίας εκλογής λοιμώξεων σε πειραματόζωα (επίμυες, μύες, κονίκλους) από πολυανθεκτικά μικρόβια

Μιχαήλ, Γ. (2013) · doi:10.12681/eadd/29239

Jeffrey Robbins

Williams, R. (2010) · Circulation Research · doi:10.1161/res.0b013e3181efec3e

Molecular Pathways and Animal Models of Cardiomyopathies

Purevjav, E. (2015) · Springer eBooks · doi:10.1007/978-3-7091-1883-2_60

Theoretical modeling of triggered activity in cardiac arrhythmias

Zhong, M. (2019) · doi:10.17760/d20328769

Methods to Induce Cardiac Hypertrophy and Insufficiency

Gralinski, M., Neves, L. A. A., & Tiniakova, O. (2014) · Springer eBooks · doi:10.1007/978-3-642-27728-3_8-1

Stretch-mediated cardiac hypertrophy and extracellular matrix remodelling

Blaauw, E. (2013) · doi:10.26481/dis.20130913eb

Transgenic Modeling of a Cardiac Troponin I Mutation Linked to Familial Hypertrophic Cardiomyopathy

James, J. F., Zhang, Y., Osińska, H. E., Sanbe, A., Klevitsky, R., Hewett, T. E., & Robbins, J. M. (2000) · Circulation Research · doi:10.1161/01.res.87.9.805 · Cited by 149 · see citing works

Molecular insights from a novel cardiac troponin I mouse model of familial hypertrophic cardiomyopathy

Tsoutsman, T., Chung, J., Doolan, A., Nguyen, L., Williams, I. A., Tu, E., Lam, L., Bailey, C. G., Rasko, J. E. J., Allen, D. G., et al. (2006) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2006.07.016 · Cited by 37 · see citing works

A transgenic rabbit model for human hypertrophic cardiomyopathy

Marian, A. J., Wu, Y., Lim, D.-S., McCluggage, M., Youker, K., Yu, Q.-T., Brugada, R., DeMayo, F., Quinones, M., & Roberts, R. (1999) · Journal of Clinical Investigation · doi:10.1172/jci7956 · Cited by 181 · see citing works

Transgenic Mice with a Low Expression Rate of the FHC Linked Mutation cTnI-ΔK184 Exhibit Predominantly Signs of Diastolic Dysfunction

Iorga, B. I., Blaudeck, N., Dávila, A. J. L., Moellendorf, S., Gödecke, A., Stehle, R., & Pfitzer, G. (2012) · Biophysical Journal · doi:10.1016/j.bpj.2011.11.3049

Functional Consequences of the Human Cardiac Troponin I Hypertrophic Cardiomyopathy Mutation R145G in Transgenic Mice

Wen, Y., Pinto, J. R., Gomes, A. V., Xu, Y., Wang, Y., Wang, Y., Potter, J. D., & Kerrick, W. G. L. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m801661200 · Cited by 60 · see citing works