Cited by 147Cardiac Arrhythmias and TreatmentsCardiac electrophysiology and arrhythmiasCongenital Heart Disease Studies

The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.

Familial Occurrence of Accessory Atrioventricular Pathways (Preexcitation Syndrome)

Vidaillet, Humberto J., Pressley, Joyce C., Henke, Elizabeth, Harrell, Frank E., German, Lawrence D.·1987·New England Journal of Medicine

DOI 10.1056/nejm198707093170201

Open this paper in CoChat — free account

Abstract

Accessory atrioventricular pathways, the anatomical structures responsible for the preexcitation syndromes, may result from a developmental failure to eradicate the remnants of the atrioventricular connections present during cardiogenesis. To study whether preexcitation syndromes could also be transmitted genetically, we determined the prevalence of preexcitation in the first-degree relatives of 383 of 456 consecutive patients (84 percent) with electrophysiologically proved accessory pathways. We compared the observed prevalence of preexcitation among the 2343 first-degree relatives with the frequency reported in the general population (0.15 percent). For 13 of the 383 index patients (3.4 percent), accessory pathways were documented in one or more first-degree relatives. At least 13 of the 2343 relatives identified (0.55 percent) had preexcitation; this prevalence was significantly higher than that in the general population (P less than 0.0001). Identification of affected relatives may have been incomplete because clinical information was obtained only about symptomatic relatives. Patients with familial preexcitation have a higher incidence of multiple accessory pathways and possibly an increased risk of sudden cardiac death. Our data suggest a hereditary contribution to the development of accessory pathways in humans. The pattern of inheritance appears to be autosomal dominant.

Integrity signals

Registry

Crossref · 10.1056/nejm198707093170201

Cites

18 of 18 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Aviat space environ med
(1992) · Applied Ergonomics · doi:10.1016/0003-6870(92)90338-v · Cited by 7,153
Ventricular fibrillation in the Wolff-Parkinson-White syndrome
Klein, G. J., Bashore, T. M., Sellers, T. D., Pritchett, E. L. C., Smith, W. M., & Gallagher, J. J. (1979) · New England Journal of Medicine · doi:10.1056/nejm197911153012003 · Cited by 830
Electrocardiographic Findings in 122,043 Individuals
Hiss, R. G., & Lamb, L. E. (1962) · Circulation · doi:10.1161/01.cir.25.6.947 · Cited by 494
The electrophysiologic basis and management of symptomatic recurrent tachycardia in patients with ebstein's anomaly of the tricuspid valve
Smith, W., Gallagher, J. J., Kerr, C. R., Sealy, W. C., Kasell, J. H., Benson, D. W., Reiter, M. J., Sterba, R., & Grant, A. O. (1982) · The American Journal of Cardiology · doi:10.1016/0002-9149(82)90048-0 · Cited by 178
THE SYNDROME OF SHORT P R INTERVAL, APPARENT BUNDLE BRANCH BLOCK, AND ASSOCIATED PAROXYSMAL TACHYCARDIA
Hunter, A., Papp, C., & Parkinson, J. (1940) · Heart · doi:10.1136/hrt.2.2.107 · Cited by 75
The electrocardiographic syndrome of short P-R interval and broad QRS complexes
Hejtmancik, M. R., & Herrmann, G. R. (1957) · American Heart Journal · doi:10.1016/0002-8703(57)90425-8 · Cited by 72
DEVELOPMENT AND HEALING OF RICKETS IN INTRAMEMBRANOUS BONE
BAILIE, J. M., & Irving, J. T. (1955) · Acta Medica Scandinavica · doi:10.1111/j.0954-6820.1955.tb16276.x · Cited by 50
A proposed autosomal dominant method of inheritance of the Wolff-Parkinson-White syndrome and supraventricular tachycardia
Gillette, P. C., Freed, D., & McNamara, D. G. (1978) · The Journal of Pediatrics · doi:10.1016/s0022-3476(78)80511-3 · Cited by 29
Pre-excitation syndrome: Facts and theories
(1980) · American Heart Journal · doi:10.1016/0002-8703(80)90298-7 · Cited by 24
Developmental Aspects and Natural History of Preexcitation Syndromes
Dunnigan, A. (1986) · Springer eBooks · doi:10.1007/978-1-4684-7526-5_2 · Cited by 21

Show all 18 references

Research works printed but not linked: 8

Zipes DP. Specific arrhythmias: diagnosis and treatment. In: Braunwald E, ed. Heart disease. 2nd ed. Philadelphia: W.B. Saunders, 1984:718.
Critelli, 1981, G Ital Cardiol, 11, 1883
Joseph, 1958, Semaine Hopitaux Paris, 34, 552
Kupatz, 1956, Neue Oesterr Zschr Kinderh, 1, 59
Nasser, 1971, J Indiana State Med Assoc, 64, 111
Tamm, 1956, Helv Paediatr Acta, 11, 78
Öhnell, 1944, Acta Med Scand [Suppl], 152, 1
Warner, 1958, Clin Res, 6, 18

Sorted by citations

Items 101–147 of 147

Wolff-Parkinson-White Syndrome Treated with Radiofrequency Ablation in Father and His Son
Kang, B. H., Kim, H. J., Namgung, J., Kim, J. S., Hong, K. P., Park, J. E., & Seo, J. D. (2002) · Korean Circulation Journal · doi:10.4070/kcj.2002.32.8.715 · Cited by 2
Evaluation and Management of the Asymptomatic Child with Wolff–Parkinson–White
Haxel, C. S., Flyer, J. N., Silver, E. S., & Liberman, L. (2016) · Current Pediatrics Reports · doi:10.1007/s40124-016-0096-1 · Cited by 2
A New Mechanism of Supraventricular Tachycardia: Gene Mutation
Gao, J., Luo, R., & Li, X. (2025) · Current Cardiology Reviews · doi:10.2174/011573403x320610250108113731 · Cited by 2
CARDIOMYOPATHIE HYPERTROPHIQUE FAMILIALE ASSOCIÉE À UN SYNDROME DE WOLFF-PARKINSON-WHITE
Mahdhaoui, A., Bouraoui, H., Tabarki, B. M., Majdoub, M., Trimeche, B., Mahdhaoui, N., Chabrak, S., Ernez-Hajri, S., Jeridi, G., & Ammar, H. (2003) · Acta Clinica Belgica · doi:10.1179/acb.2003.58.1.008 · Cited by 1
Electrophysiological Characteristics of Accessory Pathways with Prolonged Retrograde Conduction
Lin, K., Kuo, C.-T., Luqman, N., Hsu, K., WANG, C., Hsu, T., & Lee, Y. (2004) · Pacing and Clinical Electrophysiology · doi:10.1111/j.1540-8159.2004.00616.x · Cited by 1
The Wolf-Parkinson-White ECG Pattern – Assessing the Mortality Risk
Pósán, E. (2015) · Journal of Insurance Medicine · doi:10.17849/0743-6661-45.1.48 · Cited by 1
Inherited Wolff–Parkinson–White Syndrome
Liu, Y., Xue, Y., Wu, S., & Hu, D. (2016) · Cardiovascular Innovations and Applications · doi:10.15212/cvia.2016.0002 · Cited by 1
Uso de Doador com Síndrome de Wolff-Parkinson-White no Transplante Cardíaco: Relato de Dois Casos e Revisão da Literatura
Stolf, N. A. G., Honorato, R., Fiorelli, A. I., Bacal, F., & Jatene, F. (2022) · Brazilian Journal of Transplantation · doi:10.53855/bjt.v25i3.443_pt · Cited by 1
Hypertrophic Cardiomyopathy and Wolff-Parkinson-White Syndrome in a Young African Soldier with Recurrent Syncope
Talle, M. A., Buba, F., Bonny, A., & Baba, M. M. (2019) · Case Reports in Cardiology · doi:10.1155/2019/1061065 · Cited by 1
Wolff–Parkinson–White syndrome: Review of published cases associated with head and neck/oral and maxillofacial procedures
Brooks, J. K., Howland, K. E., Coury, L. T., & Dyalram, D. (2022) · Oral Surgery · doi:10.1111/ors.12715 · Cited by 1
Use of Donor with Wolff-Parkinson-White Syndrome in Heart Transplantation: Report of Two Cases and Review of Literature
Stolf, N. A. G., Honorato, R., Fiorelli, A. I., Bacal, F., & Jatene, F. (2022) · Brazilian Journal of Transplantation · doi:10.53855/bjt.v25i3.443_en · Cited by 1
Evaluation of fetal heart rate artifacts, hemodynamics and digoxin treatment in fetal tachyarrhythmia by Doppler measurement of fetal blood flow — case report of a pre-excitation syndrome
Gonser, M., Dietl, J., Pfeiffer, K., & Clees, J. P. (1989) · Journal of Perinatal Medicine · doi:10.1515/jpme.1989.17.6.411 · Cited by 1
Absence of PRKAG2 Mutation in Isolated Familial Wolff-Parkinson-White Syndrome-A Case Report
Wang, C. S., Tsai, C., Lin, Y., Hsu, K., Tseng, C.-D., Lin, J., & Ho, Y. (2005) · Zhōnghuá mínguó xīnzàngxué huì zázhì · Cited by 1
Wolff–Parkinson–White Syndrome
Salerno, J. C. (2016) · doi:10.1002/9781119046899.ch28 · Cited by 1
Management of Arrhythmia: Medications, Electrophysiology Studies and Ablation
Zakhary, D. R., Germano, J. J., & Josephson, M. E. (2014) · Springer eBooks · doi:10.1007/978-1-4471-4956-9_16
A Case of Coronary Artery Bypass Grafting in a Patient with Wolff-Parkinson-White Syndrome
杉山, 佳., 茂, 保., 俊隆, 賀., 乗松, 東., Ozawa, N., 秋田, 作., Omoto, T., 久米, 誠., & 壮介, 木. (2006) · Japanese Journal of Cardiovascular Surgery · doi:10.4326/jjcvs.35.37
The Wolff-Parkinson-White Syndrome and the Risk of Sudden Death
Gollob, M. H., Samie, R., Birnie, D. H., Green, M. S., & Gow, R. M. (2008) · Springer eBooks · doi:10.1007/978-1-84628-854-8_46
Pérdida permanente de la preexcitación tipo Wolff-Parkinson-White
García, C. M., Ramírez, E. M., & Ramírez, F. B. (2003) · FMC - Formación Médica Continuada en Atención Primaria · doi:10.1016/s1134-2072(03)75978-7
Mapping und Ablation bei Präexzitationssyndromen
Bode, K., Arya, A., Hindricks, G., & Wetzel, U. (2009) · Der Kardiologe · doi:10.1007/s12181-009-0174-5
WHITE, Paul Dudley
Beighton, P., & Beighton, G. (1997) · Springer eBooks · doi:10.1007/978-1-4471-0925-9_96
Surgery for cardiac arrhythmias
Bennett, J. G. (1988) · BMJ · doi:10.1136/bmj.296.6638.1687
Atrioventricular Nodal Reentry Tachycardia
Bradley, D. J., Bergen, N. H. V., & LaPage, M. J. (2015) · Springer eBooks · doi:10.1007/978-1-4939-2739-5_5
Antiarrhythmic therapy in patients with additional atrioventricular connective pathways: should we remember about it in the era of catheter ablation?
Tsaregorodtsev, D. A., Vasyukov, S. S., Sedov, A. V., Beraya, M. M., & Sulimov, V. A. (2016) · Russian Journal of Cardiology and Cardiovascular Surgery · doi:10.17116/kardio20169176-81
The Genetics of Cardiac Electrophysiology in Humans
Pyeritz, R. E. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-383834-6.00057-4
Electrophysiology, Pacing, and Devices
Stephenson, E. A., & Davis, A. M. (2009) · Elsevier eBooks · doi:10.1016/b978-0-7020-3064-2.00022-9
Asymptomatische ventrikuläre Präexzitation – was tun?
Hessling, G. (2019) · Kardiologie up2date · doi:10.1055/a-0674-6726
Atrio-ventricularis reentry tachycardia az AV-csomó kihagyásával, avagy kettős járulékos köteg fiatal, egészséges betegnél
Piros, K., Nagy, K. V., Szegedi, N., Osztheimer, I., Salló, Z., Perge, P., Herczeg, S., Merkely, B. P., & Gellér, L. (2019) · Cardiologia Hungarica · doi:10.26430/chungarica.2019.49.3.178
Inherited Cardiomyopathies
Teekakirikul, P., Ho, C. Y., & Seidman, C. E. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-383834-6.00053-7
Ventricular Preexcitation in a Patient Found to Have Wolff-Parkinson-White Pattern
Thakkar, A., Scheinman, M. M., & Goldschlager, N. (2020) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2020.6847
Lexikalischer Teil
Witköwski, R., Prokop, O., Ullrich, E., & Thiel, G. (2003) · Springer eBooks · doi:10.1007/978-3-642-55694-4_5
Preexcitation
Wellens, H. J. J. (2007) · Springer eBooks · doi:10.1007/978-1-84628-715-2_96
CACNA1B gain-of-function mutation drives familial atrioventricular nodal re-entrant tachycardia through sympathetic hyperactivityPreprint
Luo, R., Cao, X., Zheng, C., Tang, Y., Tang, Q., Sheng, Q., Deng, H., Yao, L., Yang, Z., Lim, W.-W., et al. (2022) · medRxiv · doi:10.1101/2022.03.09.22271906
The Wolff-Parkinson-White Syndrome and the Risk of Sudden Death
Gollob, M. H., Samie, R., Birnie, D. H., Green, M. S., & Gow, R. M. (2013) · Springer eBooks · doi:10.1007/978-1-4471-4978-1_5
Préexcitations ventriculaires
Savouré, A., Verdonck, A., & Anselme, F. (2006) · EMC - Cardiologie · doi:10.1016/s1166-4568(04)31222-2
Management of Arrhythmia: Medications, Electrophysiology Studies, and Ablation
Zakhary, D. R., & Germano, J. J. (2018) · Springer eBooks · doi:10.1007/978-3-319-92423-6_21
Préexcitations ventriculaires
Savouré, A., Verdonck, A., & Anselme, F. (2004) · EMC - Cardiologie-Angéiologie · doi:10.1016/j.emcaa.2004.08.007
Preexcitation Syndrome
Lenarczyk, R., Kowalski, O., & Kalarus, Z. (2009) · Springer eBooks · doi:10.1007/978-3-540-29676-8_1452
Tachycardia, Supraventricular
Shah, A. N., & Kantharia, B. K. (2009) · Springer eBooks · doi:10.1007/978-3-540-29676-8_1694
Atrioventricular (AV) Reentry Tachycardia
Kolditz, D. P., Jongbloed, M. R. M., & Schalij, M. J. (2010) · Springer eBooks · doi:10.1007/978-1-84996-471-5_16
Uso de Donante con Síndrome de Wolff-Parkinson-White en Trasplante de Corazón: Informe de dos Casos y Revisión de la Bibliografía
Stolf, N. A. G., Honorato, R., Fiorelli, A. I., Bacal, F., & Jatene, F. (2022) · Brazilian Journal of Transplantation · doi:10.53855/bjt.v25i3.443_esp
„Asymptomatisches WPW“
Hessling, G., Telishevska, M., Lengauer, S., & Deisenhofer, I. (2023) · Herzschrittmachertherapie + Elektrophysiologie · doi:10.1007/s00399-023-00930-x
Incidental WPW Pattern in a Patient of Acute Coronary Syndrome: Case Report and Review of Literature
Mehrotra, A., Sharma, A., & Kacker, S. (2023) · International Journal of Research and Review · doi:10.52403/ijrr.20230364
Accessory pathways in monozygotic twins with different clinical phenotypes: a case report
Marzak, H., Fitouchi, S., Cardi, T., Kanso, M., Schatz, A., & Jesel, L. (2023) · International Journal of Arrhythmia · doi:10.1186/s42444-023-00091-5
Familial Occurrence of Atrioventricular Nodal Reentrant Tachycardia in Mother, Father and Their Daughter
Tekinşen, K., Sucu, M., & Yıldırım, A. (2023) · Bulletin of Cardiovasculer Academy · doi:10.4274/kvbulten.galenos.2023.00719
A rare genetic variant in PRDM16 is associated with Wolff–Parkinson–White syndrome with complex accessory pathway characteristics and left ventricular non-compaction cardiomyopathy
Umapathi, K. K., Schmidt, S. B., & Kohli, U. (2025) · Cardiology in the Young · doi:10.1017/s1047951124036631
A Review of Wolff-Parkinson-White for the General Practitioner
Corral, I., & Perez-Corral, C. (2025) · Advances in Pediatrics · doi:10.1016/j.yapd.2025.03.007
Management of Arrhythmia: Medications, Diagnostic Studies, and Catheter Ablation
Iwai, S., Germano, J. J., & Jacobson, J. T. (2025) · Springer eBooks · doi:10.1007/978-3-031-99282-7_22

Authors: Vidaillet, H. J., Pressley, J. C., Henke, E., Harrell, F. E., & German, L. D.
ORCID: Pressley, Joyce C.
Harrell, Frank E.
Venue: New England Journal of Medicine
Publisher: Massachusetts Medical Society
Published: 1987-07-09
Volume: 317
Issue: 2
Pages: 65-69
ISSN: 0028-4793 (ISSN-L)
1533-4406
DOI: 10.1056/nejm198707093170201
OpenAlex: W2335789543
Cited by: 147
References: 18
Citations by year: 2026: 1 · 2025: 6 · 2024: 2 · 2023: 4 · 2022: 9 · 2021: 1 · 2020: 5 · 2019: 6 · 2018: 5 · 2017: 1 · 2016: 6 · 2015: 2 · 2014: 1 · 2013: 7 · 2012: 6
FWCI: 3.72
Type: journal article
Language: en
Open access: closed
Locations: New England Journal of Medicine (publishedVersion)
PubMed (publishedVersion)
Funders: Agency for Healthcare Research and Quality (HS-03834)
National Heart, Lung, and Blood Institute (HL 07063, HL17670)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Arrhythmias and Treatments
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Congenital Heart Disease Studies
Keywords: accessory pathway, preexcitation syndrome, Wolff-Parkinson-White syndrome, familial occurrence, genetic transmission, autosomal dominant inheritance, first-degree relatives, multiple accessory pathways, sudden cardiac death, heart development
MeSH terms: Death, Sudden, Female, Heart Conduction System, Heart Diseases, Humans, Male, Pedigree, Pre-Excitation Syndromes, Sex Factors, United States

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Familial Occurrence of Accessory Atrioventricular Pathways (Preexcitation Syndrome)

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks