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Cited by 499

The DOI matches its Crossref record; 15 of the 15 references it cites were found in a registry or an index.

Shock-Wave Lithotripsy of Gallbladder Stones

Sackmann, Michael, Delius, Michael, Sauerbruch, Tilman, Holl, Joseph, Weber, Werner, Ippisch, Ernst, Hagelauer, Ulrich, Wess, Othmar, Hepp, Wolfgang, Brendel, Walter, Paumgartner, Gustav·1988·New England Journal of Medicine

Abstract

To substantiate the early results of extracorporeal shock-wave fragmentation of gallstones, we used this nonsurgical procedure to treat 175 patients with radiolucent gallbladder calculi. Chenodeoxycholic acid and ursodeoxycholic acid were administered as adjuvant litholytic therapy. The gallstones disintegrated in all patients except one and completely disappeared in 30 percent of all patients within 2 months after lithotripsy, in 48 percent at 2 to 4 months, in 63 percent at 4 to 8 months, in 78 percent at 8 to 12 months, and in 91 percent at 12 to 18 months. In patients with solitary stones up to 20 mm in diameter, the corresponding values were 45, 69, 78, 86, and 95 percent, respectively. Shock-wave therapy had no adverse effects except cutaneous petechiae (14 percent) and transient gross hematuria (3 percent). One third of the patients had one or more episodes of biliary colic before all the fragments disappeared. Two patients had mild pancreatitis, which necessitated endoscopic sphincterotomy in one. The patient with insufficient stone fragmentation underwent elective cholecystectomy; no additional operations were necessary. Extracorporeal shock-wave lithotripsy combined with medical therapy for stone dissolution is a safe and effective treatment in selected patients with radiolucent gallbladder calculi.

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Metadata

Authors
Sackmann, M., Delius, M., Sauerbruch, T., Holl, J., Weber, W., Ippisch, E., Hagelauer, U., Wess, O., Hepp, W., Brendel, W., & Paumgartner, G.
Venue
New England Journal of Medicine
Published
1988-02-18
Volume
318
Issue
7
Pages
393-397
ISSN
  • 0028-4793 (ISSN-L)
  • 1533-4406
OpenAlex
W2329230000
Cited by
499
References
15
FWCI
133.58
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Shock-Wave Lithotripsy of Gallbladder Stones. https://app.cochat.ai/papers/10.1056/nejm198802183180701
The paper
Sackmann, M., Delius, M., Sauerbruch, T., Holl, J., Weber, W., Ippisch, E., Hagelauer, U., Wess, O., Hepp, W., Brendel, W., & Paumgartner, G. (1988). Shock-Wave Lithotripsy of Gallbladder Stones. New England Journal of Medicine. https://doi.org/10.1056/nejm198802183180701

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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