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Cited by 493

The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.

Local and Systemic Factors in the Pathogenesis of Osteoporosis

Epstein, Franklin H., Raisz, Lawrence G.·1988·New England Journal of Medicine

Abstract

OSTEOPOROSIS is defined as a decrease in bone mass and strength leading to an increase in fractures, particularly of the vertebral bodies, proximal femur, and distal radius. According to this definition, the disorder must exist before the fracture occurs, but at present we cannot reliably diagnose osteoporosis before a fracture. Moreover, most hip and wrist fractures occur after a fall, and if there is no trauma the osteoporosis may never become clinically apparent. Even in vertebral crush fractures, which usually occur with little or no trauma, the defect in bone mass and strength may exist for years before fracture occurs. . . .

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Crossref · 10.1056/nejm198803313181305

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Metadata

Authors
Epstein, F. H., & Raisz, L. G.
Venue
New England Journal of Medicine
Published
1988-03-31
Volume
318
Issue
13
Pages
818-828
ISSN
  • 0028-4793 (ISSN-L)
  • 1533-4406
OpenAlex
W2068872959
Cited by
493
References
5
FWCI
48.14
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Local and Systemic Factors in the Pathogenesis of Osteoporosis. https://app.cochat.ai/papers/10.1056/nejm198803313181305
The paper
Epstein, F. H., & Raisz, L. G. (1988). Local and Systemic Factors in the Pathogenesis of Osteoporosis. New England Journal of Medicine. https://doi.org/10.1056/nejm198803313181305

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.