Cited by 156Cardiac Arrhythmias and TreatmentsCardiac electrophysiology and arrhythmiasCardiac pacing and defibrillation studies

The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.

Longitudinal Electrophysiologic Assessment of Asymptomatic Patients with the Wolff–Parkinson–White Electrocardiographs Pattern

Klein, George J., Yee, Raymond, Sharma, Arjun D.·1989·New England Journal of Medicine

DOI 10.1056/nejm198905113201901

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Abstract

Although most asymptomatic patients with the Wolff-Parkinson-White electrocardiographic pattern have a good prognosis, some die suddenly. The mechanism of sudden death is usually ventricular fibrillation, which is triggered by atrial fibrillation with a rapid ventricular response rate. Electrophysiologic testing has been proposed to identify asymptomatic patients who may be at risk for sudden death. Meaningful application of such testing requires a knowledge of whether the electrophysiologic measurements are reproducible over time. Consequently, we performed electrophysiologic studies on two occasions at least 36 months apart (mean +/- SD, 54.7 +/- 14) in 29 asymptomatic patients with the pattern. Twenty-seven patients remained asymptomatic, and sustained supraventricular tachycardia developed in two during the follow-up period. Nine patients (31 percent) lost the capacity for preexcitation and anterograde conduction over the accessory pathway, which produces the Wolff-Parkinson-White pattern. The others had little change in measurements of conduction over the accessory pathway. Patients who lost conduction over the accessory pathway tended to be older (mean +/- SD, 50 +/- 18 vs. 39 +/- 11 years; P = 0.06) than patients who retained preexcitation, and they had longer anterograde effective refractory periods at the first assessment (414 +/- 158 vs. 295 +/- 27 msec; P = 0.003). We conclude that a considerable number of asymptomatic patients with the Wolff-Parkinson-White pattern lose their capacity for anterograde conduction over the accessory pathway. This loss of capacity probably contributes to the low mortality among asymptomatic patients.

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Ventricular fibrillation in the Wolff-Parkinson-White syndrome
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Self-citation
Intermittent preexcitation in the wolff-parkinson-white syndrome
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Self-citation
An Algorithm for the Electrocardiographic Localization of Accessory Pathways in the Wolff‐Parkinson‐White Syndrome
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Self-citation
The Wolff–Parkinson–White Electrocardiogram
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Self-citation
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(1980) · American Heart Journal · doi:10.1016/0002-8703(80)90298-7 · Cited by 24

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Guize, 1985, Ann Med Interne (Paris), 136, 474
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Authors: Klein, G. J., Yee, R., & Sharma, A. D.
Affiliations: London Health Sciences Centre (CA)
ORCID: Klein, George J.
Yee, Raymond
Sharma, Arjun D.
Venue: New England Journal of Medicine
Publisher: Massachusetts Medical Society
Published: 1989-05-11
Volume: 320
Issue: 19
Pages: 1229-1233
ISSN: 0028-4793 (ISSN-L)
1533-4406
DOI: 10.1056/nejm198905113201901
OpenAlex: W2340334067
Cited by: 156
References: 11
Citations by year: 2026: 1 · 2024: 3 · 2023: 1 · 2022: 1 · 2021: 3 · 2020: 2 · 2019: 4 · 2018: 4 · 2017: 7 · 2016: 3 · 2015: 13 · 2014: 3 · 2013: 4 · 2012: 10
FWCI: 6.18
Type: journal article
Language: en
Open access: closed
Locations: New England Journal of Medicine (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Arrhythmias and Treatments
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac pacing and defibrillation studies
Keywords: Wolff-Parkinson-White syndrome, asymptomatic patients, accessory pathway, preexcitation, effective refractory period, sudden cardiac death, ventricular fibrillation, atrial fibrillation, supraventricular tachycardia
MeSH terms: Atrial Fibrillation, Electrocardiography, Female, Heart Conduction System, Humans, Longitudinal Studies, Male, Middle Aged, Refractory Period, Electrophysiological, Ventricular Fibrillation, Wolff-Parkinson-White Syndrome

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Longitudinal Electrophysiologic Assessment of Asymptomatic Patients with the Wolff–Parkinson–White Electrocardiographs Pattern

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