The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
High Blood Alcohol Levels in Women
Abstract
Abstract After consuming comparable amounts of ethanol, women have higher blood ethanol concentrations than men, even with allowance for differences in size, and are more susceptible to alcoholic liver disease. Recently, we documented significant of ethanol due to its oxidation by gastric tissue. We report a study of the possible contribution of this metabolism to the sex-related difference in blood alcohol concentrations in 20 men and 23 women. Six in each group were alcoholics. The first-pass metabolism was determined on the basis of the difference in areas under the curves of blood alcohol concentrations after intravenous and oral administration of ethanol (0.3 g per kilogram of body weight). Alcohol dehydrogenase activity was also measured in endoscopic gastric biopsies. In nonalcoholic subjects, the first-pass metabolism and gastric alcohol dehydrogenase activity of the women were 23 and 59 percent, respectively, of those in the men, and there was a significant correlation (rs...
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Citations
Cites
Frezza, M., di Padova, C., Pozzato, G., Terpin, M., Baraona, E., & Lieber, C. S. (1990) · New England Journal of Medicine · doi:10.1056/nejm199001113220205 · Cited by 1,328
Korsten, M. A., Matsuzaki, S., Feinman, L., & Lieber, C. S. (1975) · New England Journal of Medicine · doi:10.1056/nejm197502202920802 · Cited by 518
Clinical Pharmacokinetics of Ethanol
Holford, N. H. G. (1987) · Clinical Pharmacokinetics · doi:10.2165/00003088-198713050-00001 · Cited by 283
Cited by
Franz, M. J., Bantle, J. P., Beebe, C. A., Brunzell, J. D., Chiasson, J.-L., Garg, A., Holzmeister, L. A., Hoogwerf, B., Mayer-Davis, E., Mooradian, A. D., et al. (2002) · Diabetes Care · doi:10.2337/diacare.25.1.148 · Cited by 1,165
EASL Clinical Practical Guidelines: Management of Alcoholic Liver Disease
European Association for the Study of the Liver (2012) · Journal of Hepatology · doi:10.1016/j.jhep.2012.04.004 · Cited by 720
Alcoholic fatty liver: its pathogenesis and mechanism of progression to inflammation and fibrosis
Lieber, C. S. (2004) · Alcohol · doi:10.1016/j.alcohol.2004.07.008 · Cited by 699
Donato, F. (2002) · American Journal of Epidemiology · doi:10.1093/aje/155.4.323 · Cited by 677
Drinking habits as cofactors of risk for alcohol induced liver damage
Bellentani, S., Saccoccio, G., Costa, G., Tiribelli, C., Manenti, F., Sodde, M., Croce’, L. S., Sasso, F., Pozzato, G., Cristianini, G., et al. (1997) · Gut · doi:10.1136/gut.41.6.845 · Cited by 630
Metadata
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1990-07-05
- Volume
- 323
- Issue
- 1
- Pages
- 58-62
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2331931199
- Cited by
- 289
- References
- 3
- FWCI
- 11.38
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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