The DOI matches its Crossref record; 25 of the 25 references it cites were found in a registry or an index.
Effect of Restricting Dietary Protein on the Progression of Renal Failure in Patients with Insulin-Dependent Diabetes Mellitus
Abstract
BACKGROUND: Restriction of dietary protein may slow the progression of renal failure in diverse renal diseases, but the extent to which such a diet is beneficial in patients with diabetic nephropathy is uncertain. METHODS: We studied the effect of reduced intake of protein and phosphorus on the progression of renal disease in 35 patients with insulin-dependent (Type I) diabetes mellitus and clinically evident nephropathy. The low-protein, low-phosphorus diet contained 0.6 g of protein per kilogram of ideal body weight per day, 500 to 1000 mg of phosphorus, and 2000 mg of sodium. The control diet consisted of the patient's prestudy diet with the stipulation that it contain 2000 mg of sodium and at least 1 g of protein per kilogram per day and 1000 mg of phosphorus. Renal function was assessed by measurement of iothalamate and creatinine clearances at intervals of 3 to 6 months, and the patients were followed for a minimum of 12 months (mean, 34.7). The declines in mean glomerular filtration rates were compared between groups by linear-regression analysis of the glomerular filtration rate as a function of time. RESULTS: The patients who followed the study diet for a mean of 37.1 months had declines in iothalamate clearance of 0.0043 ml per second per month and in creatinine clearance of 0.0055 ml per second per month. The comparable values in the control group were 0.0168 and 0.0135, respectively (P less than 0.05). Blood pressure was well controlled, and the degree of glycemic control was comparable in both groups. CONCLUSION: Dietary restriction of protein and phosphorus can retard the progression of renal failure in patients with Type I diabetes mellitus who have nephropathy. We believe that wider use of this treatment is indicated.
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Cites
Diabetic nephropathy in type 1 (insulin-dependent) diabetes: An epidemiological study
Andersen, A. R., Christiansen, J. S., Andersen, J. K., Kreiner, S., & Deckert, T. (1983) · Diabetologia · doi:10.1007/bf00284458 · Cited by 1,067
Parving, H.-H., Smidt, U., Andersen, A., & Svendsen, P. (1983) · The Lancet · doi:10.1016/s0140-6736(83)92462-5 · Cited by 867
A method for estimating nitrogen intake of patients with chronic renal failure
Maroni, B. J., Steinman, T. I., & Mitch, W. E. (1985) · Kidney International · doi:10.1038/ki.1985.10 · Cited by 780
Long-term antihypertensive treatment inhibiting progression of diabetic nephropathy
Mogensen, C. E. (1982) · BMJ · doi:10.1136/bmj.285.6343.685 · Cited by 760
PROSPECTIVE RANDOMISED TRIAL OF EARLY DIETARY PROTEIN RESTRICTION IN CHRONIC RENAL FAILURE
Rosman, J., Ter Wee, P., Meijer Truus, S., Piers-Becht, P. M., Sluiter, W., & Donker, A. M. (1984) · The Lancet · doi:10.1016/s0140-6736(84)90818-3 · Cited by 555
Deckert, T., Poulsen, J. E., & Larsen, M. (1978) · Diabetologia · doi:10.1007/bf01228130 · Cited by 471
Bjorck, S., Nyberg, G., Mulec, H., Granerus, G., Herlitz, H., & Aurell, M. (1986) · BMJ · doi:10.1136/bmj.293.6545.471 · Cited by 405
Dorman, J. S., Laporte, R. E., Kuller, L. H., Cruickshanks, K. J., Orchard, T. J., Wagener, D. K., Becker, D. J., Cavender, D. E., & Drash, A. L. (1984) · Diabetes · doi:10.2337/diab.33.3.271 · Cited by 350
Preservation of Function in Experimental Renal Disease by Dietary Restriction of Phosphate
Ibels, L. S., Alfrey, A. C., Haut, L., & Huffer, W. E. (1978) · New England Journal of Medicine · doi:10.1056/nejm197801192980302 · Cited by 296
Effects of dietary protein and phosphorus restriction on the progression of early renal failure
Maschio, G., Oldrizzi, L., Tessitore, N., D'Angelo, A., Valvo, E., Lupo, A., Loschiavo, C., Fabris, A., Gammaro, L., Rugiu, C., et al. (1982) · Kidney International · doi:10.1038/ki.1982.184 · Cited by 229
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KDOQI clinical practice guideline for nutrition in CKD: 2020 update
Ikizler, T. A., Burrowes, J. D., Byham-Gray, L. D., Campbell, K. L., Carrero, J.-J., Chan, W., Fouque, D., Friedman, A. N., Ghaddar, S., Goldstein-Fuchs, D. J., et al. (2020) · American Journal of Kidney Diseases · doi:10.1053/j.ajkd.2020.05.006 · Cited by 1,960
KDIGO 2020 Clinical practice guideline for diabetes management in chronic kidney disease
de Boer, I. H., Caramori, M. L., Chan, J. C. N., Heerspink, H. J. L., Hurst, C., Khunti, K., Liew, A., Michos, E. D., Navaneethan, S. D., Olowu, W. A., et al. (2020) · Kidney International · doi:10.1016/j.kint.2020.06.019 · Cited by 1,399
KDIGO 2022 Clinical Practice Guideline for Diabetes Management in Chronic Kidney Disease
Rossing, P., Caramori, M. L., Chan, J. C. N., Heerspink, H. J. L., Hurst, C., Khunti, K., Liew, A., Michos, E. D., Navaneethan, S. D., Olowu, W. A., et al. (2022) · Kidney International · doi:10.1016/j.kint.2022.06.008 · Cited by 1,373
Franz, M. J., Bantle, J. P., Beebe, C. A., Brunzell, J. D., Chiasson, J.-L., Garg, A., Holzmeister, L. A., Hoogwerf, B., Mayer-Davis, E., Mooradian, A. D., et al. (2002) · Diabetes Care · doi:10.2337/diacare.25.1.148 · Cited by 1,165
The modification of diet in renal disease study group
Beck, G. J., Berg, R. L., Coggins, C. H., Gassman, J. J., Hunsicker, L. G., Schluchter, M. D., & Williams, G. W. (1991) · Controlled Clinical Trials · doi:10.1016/0197-2456(91)90069-x · Cited by 818
Metadata
- Authors
- Zeller, K., Whittaker, E., Sullivan, L., Raskin, P., & Jacobson, H. R.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1991-01-10
- Volume
- 324
- Issue
- 2
- Pages
- 78-84
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2330121013
- Cited by
- 409
- References
- 25
- FWCI
- 36.39
- Type
- journal article
- Language
- en
- Open access
- closed
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- Zeller, K., Whittaker, E., Sullivan, L., Raskin, P., & Jacobson, H. R. (1991). Effect of Restricting Dietary Protein on the Progression of Renal Failure in Patients with Insulin-Dependent Diabetes Mellitus. New England Journal of Medicine. https://doi.org/10.1056/nejm199101103240202
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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