The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Beneficial effects of angiotensin converting enzyme inhibition on renal function in patients with diabetic nephropathy.
Open accessAbstract
The effects of angiotensin converting enzyme inhibition with captopril were investigated in patients with diabetic nephropathy and hypertension. After nine days' treatment with captopril glomerular filtration rate was unchanged in 13 patients, whereas renal plasma flow had increased from 265 to 302 ml/min/1.73 m2 body surface area (p less than 0.05) and the filtration fraction had decreased from 14.3 to 12.8% (p less than 0.025). During two years' treatment with captopril in 14 patients the mean arterial blood pressure had fallen by 5 mm Hg (p less than 0.005) and the deterioration in glomerular filtration rate had decreased from 10.3 to 2.4 ml/min/year (p less than 0.005). There was no correlation between the fall in blood pressure and the reduction in the deterioration of glomerular filtration rate. These findings suggest that the effects of angiotensin converting enzyme inhibition on renal haemodynamics protect renal function. Inhibitors of angiotensin converting enzyme should be considered for lowering blood pressure in patients with diabetic nephropathy.
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Blantz, R. C., Konnen, K. S., & Tucker, B. J. (1976) · Journal of Clinical Investigation · doi:10.1172/jci108293 · Cited by 428
Cited by
The effect of angiotensin-converting-enzyme inhibition on diabetic nephropathy
Lewis, E. J., Hunsicker, L. G., Bain, R. P., & Rohde, R. D. (1993) · New England Journal of Medicine · doi:10.1056/nejm199311113292004 · Cited by 5,394
Effect of antihypertensive treatment on kidney function in diabetic nephropathy.
Parving, H. H., Andersen, A. R., Smidt, U. M., Hommel, E., Mathiesen, E. R., & Svendsen, P. A. (1987) · BMJ · doi:10.1136/bmj.294.6585.1443 · Cited by 537
Interactions of Transforming Growth Factor-β and Angiotensin II in Renal Fibrosis
Border, W. A., & Noble, N. A. (1998) · Hypertension · doi:10.1161/01.hyp.31.1.181 · Cited by 447
Zeller, K., Whittaker, E., Sullivan, L., Raskin, P., & Jacobson, H. R. (1991) · New England Journal of Medicine · doi:10.1056/nejm199101103240202 · Cited by 409
Short and long term effects of antihypertensive therapy in the diabetic rat
Anderson, S., Rennke, H. G., Garcia, D. L., Brenner, B. M., Riley, S. L., & Sandstrom, D. J. (1989) · Kidney International · doi:10.1038/ki.1989.227 · Cited by 306
Metadata
- Authors
- Bjorck, S., Nyberg, G., Mulec, H., Granerus, G., Herlitz, H., & Aurell, M.
- Venue
- BMJ
- Publisher
- BMJ
- Published
- 1986-08-23
- Volume
- 293
- Issue
- 6545
- Pages
- 471-474
- ISSN
- 0007-1447 (ISSN-L)
- 0959-8138
- 1468-5833
- OpenAlex
- W1996485736
- Cited by
- 405
- References
- 1
- FWCI
- 30.84
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Bjorck, S., Nyberg, G., Mulec, H., Granerus, G., Herlitz, H., & Aurell, M. (1986). Beneficial effects of angiotensin converting enzyme inhibition on renal function in patients with diabetic nephropathy. BMJ. https://doi.org/10.1136/bmj.293.6545.471
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
