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Doxorubicin-Induced Cardiac Toxicity
Abstract
Doxorubicin (Adriamycin) and the related anthracycline antibiotic daunorubicin play a central part in cancer therapy because of their efficacy in the treatment of hematologic cancers (both acute leukemias and lymphomas), as well as carcinomas of the breast, lung, and thyroid and bone and soft-tissue sarcomas.1 Furthermore, these drugs are widely used in both adults and children in treatment regimens aimed at the cure of neoplasms as well as at palliation. The discovery more than 20 years ago that therapy with anthracyclines could produce irreversible and possibly life-threatening cardiac injury has led to limitations on the use of these drugs in . . .
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Citations
Cited by
Hypolipidemic, Antioxidant, and Antiinflammatory Activities of Microalgae Spirulina
Deng, R., & Chow, T. (2010) · Cardiovascular Therapeutics · doi:10.1111/j.1755-5922.2010.00200.x · Cited by 435
Cardiac spheroids as promising in vitro models to study the human heart microenvironment
Polonchuk, L., Chabria, M., Badi, L., Hoflack, J.-C., Figtree, G., Davies, M. J., & Gentile, C. (2017) · Scientific Reports · doi:10.1038/s41598-017-06385-8 · Cited by 223
Protective effect ofSpirulina against doxorubicin-induced cardiotoxicity
Khan, M., Shobha, J. C., Mohan, I. K., Naidu, M. U. R., Sundaram, C., Singh, S., Kuppusamy, P., & Kutala, V. K. (2005) · Phytotherapy Research · doi:10.1002/ptr.1783 · Cited by 159
Metadata
- Authors
- Doroshow, J. H.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1991-03-21
- Volume
- 324
- Issue
- 12
- Pages
- 843-845
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W1995054939
- Cited by
- 198
- References
- 0
- FWCI
- 10.88
- Type
- journal article
- Language
- en
- Open access
- closed
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- Doroshow, J. H. (1991). Doxorubicin-Induced Cardiac Toxicity. New England Journal of Medicine. https://doi.org/10.1056/nejm199103213241210
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
