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Treatment of Patients with Cancer of an Unknown Primary Site
Abstract
Few diagnoses in medicine engender as much pessimism as the diagnosis of metastatic cancer of an unknown primary site. Patients with this syndrome often have widespread metastatic disease, with involvement of multiple visceral sites such as the liver, lungs, and bones, and are often debilitated at the time of diagnosis. Early reports of chemotherapy in these patients documented low rates of response and no effect on the dismal median survival of three to four months, thereby strengthening arguments for a nihilistic approach14.Recently, however, the treatment of some patients with cancer of an unknown primary site has improved . . .
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Cited by
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Ramaswamy, S., Tamayo, P., Rifkin, R., Mukherjee, S., Yeang, C.-H., Angelo, M., Ladd, C., Reich, M., Latulippe, E., Mesirov, J. P., et al. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.211566398 · Cited by 2,023
MicroRNAs accurately identify cancer tissue origin
Rosenfeld, N., Aharonov, R., Meiri, E., Rosenwald, S., Spector, Y., Zepeniuk, M., Benjamin, H., Shabes, N., Tabak, S., Levy, A., et al. (2008) · Nature Biotechnology · doi:10.1038/nbt1392 · Cited by 812
Kaufmann, O., Fietze, E., Mengs, J., & Dietel, M. (2001) · American Journal of Clinical Pathology · doi:10.1309/21tw-2ndg-jrk4-pfjx · Cited by 324
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Metadata
- Authors
- Wood, A. J. J., Hainsworth, J. D., & Greco, F. A.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1993-07-22
- Volume
- 329
- Issue
- 4
- Pages
- 257-263
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2333179120
- Cited by
- 233
- References
- 0
- FWCI
- 2.08
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Treatment of Patients with Cancer of an Unknown Primary Site. https://app.cochat.ai/papers/10.1056/nejm199307223290407
- The paper
- Wood, A. J. J., Hainsworth, J. D., & Greco, F. A. (1993). Treatment of Patients with Cancer of an Unknown Primary Site. New England Journal of Medicine. https://doi.org/10.1056/nejm199307223290407
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.