The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Aspirin as an Antiplatelet Drug
Abstract
The past 10 years have witnessed major changes in our understanding of the pathophysiologic mechanisms underlying vascular occlusion1,2 and considerable progress in the clinical assessment of aspirin and other antiplatelet agents35. The purpose of this review is to describe a rational basis for antithrombotic prophylaxis and treatment with aspirin. Basic information on the molecular mechanism of action of aspirin in inhibiting platelet function will be integrated with the appropriate clinical pharmacologic data and the results of randomized clinical trials.Mechanism of ActionAspirin induces a long-lasting functional defect in platelets, clinically detectable as a prolongation of the . . .
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Citations
Cites
Platelet Activation in Unstable Coronary Disease
Fitzgerald, D. J., Roy, L., Catella, F., & FitzGerald, G. A. (1986) · New England Journal of Medicine · doi:10.1056/nejm198610163151602 · Cited by 1,141
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Cyclooxygenases: Structural, cellular, and molecular biology
Smith, W. L., DeWitt, D. L., & Garavito, R. M. (2000) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.69.1.145 · Cited by 2,925
A meta-analysis of randomized controlled trials: Efficacy of selenium treatment for sepsis
Li, S., Tang, T., Guo, P., Zou, Q., Ao, X., Hu, L., & Tan, L. (2019) · Medicine · doi:10.1097/md.0000000000014733 · Cited by 802
ACOG Committee Opinion No. 743: Low-Dose Aspirin Use During Pregnancy
(2018) · Obstetrics & Gynecology · doi:10.1097/aog.0000000000002708 · Cited by 711
Platelet activation in type 2 diabetes mellitus
Ferroni, P., Basili, S., Falco, A., & Davì, G. (2004) · Journal of Thrombosis and Haemostasis · doi:10.1111/j.1538-7836.2004.00836.x · Cited by 493
Jennings, L. (2009) · Thrombosis and Haemostasis · doi:10.1160/th09-03-0192 · Cited by 436
Metadata
- Authors
- Wood, A. J. J., & Patrono, C.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1994-05-05
- Volume
- 330
- Issue
- 18
- Pages
- 1287-1294
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2331216347
- Cited by
- 955
- References
- 1
- FWCI
- 29.95
- Type
- journal article
- Language
- en
- Open access
- closed
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- Wood, A. J. J., & Patrono, C. (1994). Aspirin as an Antiplatelet Drug. New England Journal of Medicine. https://doi.org/10.1056/nejm199405053301808
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.