The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.
Treatment of Adult T-Cell Leukemia–Lymphoma with a Combination of Interferon Alfa and Zidovudine
Open accessAbstract
BACKGROUND: Infection with the human T-cell lymphotropic virus type I, a retrovirus, can cause a distinctive cancer, adult T-cell leukemia-lymphoma. The median survival of patients with the acute and lymphomatous forms of the disease is short, despite the use of cytotoxic chemotherapy. METHODS: We treated 19 patients with acute or lymphomatous forms of adult T-cell leukemia-lymphoma with oral zidovudine (200 mg five times daily) and interferon alfa (Intron A, 5 to 10 million units subcutaneously each day). Seven of these patients had either relapsed after multiagent cytotoxic chemotherapy or failed to respond to that treatment. RESULTS: Major responses were achieved in 58 percent of the patients (11 of 19), including complete remission in 26 percent (5 of 19). Four patients in whom prior cytotoxic therapy had failed had major responses, two of which were complete remissions. Six patients have survived for more than 12 months, with the longest remission since the discontinuation of treatment lasting more than 59 months. CONCLUSIONS: The combination of zidovudine and interferon alfa has activity against adult T-cell leukemia-lymphoma, even in patients in whom prior cytotoxic therapy has failed. This regimen should be evaluated further for its role in the treatment of adult T-cell leukemia-lymphoma.
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Cites
The Statistical Analysis of Failure Time Data.
Aitkin, M., Kalbfleisch, J. D., & Prentice, R. L. (1981) · Biometrics · doi:10.2307/2530581 · Cited by 9,877
Poiesz, B. J., Ruscetti, F. W., Gazdar, A. F., Bunn, P. A., Minna, J. D., & Gallo, R. C. (1980) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.77.12.7415 · Cited by 5,043
Adult T-cell leukemia: clinical and hematologic features of 16 cases
Uchiyama, T., Yodoi, J., Sagawa, K., Takatsuki, K., & Uchino, H. (1977) · Blood · doi:10.1182/blood.v50.3.481.481 · Cited by 2,316
Shimoyama, M., & members of The Lymphoma Study Group (1984–87) (1991) · British Journal of Haematology · doi:10.1111/j.1365-2141.1991.tb08051.x · Cited by 1,608
Furman, P. A., Fyfe, J. A., St Clair, M. H., Weinhold, K., Rideout, J. L., Freeman, G. A., Lehrman, S. N., Bolognesi, D. P., Broder, S., & Mitsuya, H. (1986) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.83.21.8333 · Cited by 1,347
On distribution-free tests for equality of survival distributions
TARONE, R. E., & WARE, J. (1977) · Biometrika · doi:10.1093/biomet/64.1.156 · Cited by 729
Friedman, R. L., Manly, S. P., McMahon, M., Kerr, I. M., & Stark, G. R. (1984) · Cell · doi:10.1016/0092-8674(84)90270-8 · Cited by 718
Hinuma, Y., Komoda, H., Chosa, T., Kondo, T., Kohakura, M., Takenaka, T., Kikuchi, M., Ichimaru, M., Yunoki, K., Sato, I., et al. (1982) · International Journal of Cancer · doi:10.1002/ijc.2910290606 · Cited by 591
Blattner, W. A., Kalyanaraman, V. S., Robert‐Guroff, M., Lister, T. A., Galton, D. A. G., Sarin, P. S., Crawford, M. H., Catovsky, D., Greaves, M., & Gallo, R. C. (1982) · International Journal of Cancer · doi:10.1002/ijc.2910300302 · Cited by 578
A Network Algorithm for Performing Fisher's Exact Test in r × c Contingency Tables
Mehta, C. R., & Patel, N. R. (1983) · Journal of the American Statistical Association · doi:10.2307/2288652 · Cited by 538
Cited by
Ishida, T., Joh, T., Uike, N., Yamamoto, K., Utsunomiya, A., Yoshida, S., Saburi, Y., Miyamoto, T., Takemoto, S., Suzushima, H., et al. (2012) · Journal of Clinical Oncology · doi:10.1200/jco.2011.37.3472 · Cited by 657
Tsukasaki, K., Hermine, O., Bazarbachi, A., Ratner, L., Ramos, J. C., Harrington, W., O’Mahony, D., Janik, J. E., Bittencourt, A. L., Taylor, G. P., et al. (2009) · Journal of Clinical Oncology · doi:10.1200/jco.2008.18.2428 · Cited by 558
Self-citationTsukasaki, K., Utsunomiya, A., Fukuda, H., Shibata, T., Fukushima, T., Takatsuka, Y., Ikeda, S., Masuda, M., Nagoshi, H., Ueda, R., et al. (2007) · Journal of Clinical Oncology · doi:10.1200/jco.2007.11.9958 · Cited by 493
Bazarbachi, A., Plumelle, Y., Carlos Ramos, J., Tortevoye, P., Otrock, Z., Taylor, G., Gessain, A., Harrington, W., Panelatti, G., & Hermine, O. (2010) · Journal of Clinical Oncology · doi:10.1200/jco.2010.28.0669 · Cited by 373
Self-citationMolecular mechanisms of human T-cell leukemia/lymphotropic virus type I infection
Franchini, G. (1995) · Blood · doi:10.1182/blood.v86.10.3619.bloodjournal86103619 · Cited by 360
Metadata
- Authors
- Gill, P. S., Harrington, W., Kaplan, M. H., Ribeiro, R. C., Bennett, J. M., Liebman, H. A., Bernstein-Singer, M., Espina, B. M., Cabral, L., Allen, S., Kornblau, S., Pike, M. C., & Levine, A. M.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1995-06-29
- Volume
- 332
- Issue
- 26
- Pages
- 1744-1748
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W1995670792
- Cited by
- 372
- References
- 23
- FWCI
- 5.27
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Gill, P. S., Harrington, W., Kaplan, M. H., Ribeiro, R. C., Bennett, J. M., Liebman, H. A., Bernstein-Singer, M., Espina, B. M., Cabral, L., Allen, S., Kornblau, S., Pike, M. C., & Levine, A. M. (1995). Treatment of Adult T-Cell Leukemia–Lymphoma with a Combination of Interferon Alfa and Zidovudine. New England Journal of Medicine. https://doi.org/10.1056/nejm199506293322603
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
