The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
Acute Non-A–E Hepatitis in the United States and the Role of Hepatitis G Virus Infection
Open accessAbstract
BACKGROUND: Little is known about the relation of the newly discovered hepatitis G virus (HGV) to the cause and clinical course of acute and chronic viral hepatitis. METHODS: We selected patients from a surveillance study of acute viral hepatitis in four U.S. counties who had acute disease during 1985 to 1986 or 1991 to 1995. Serum samples were tested for HGV RNA by the polymerase chain reaction. RESULTS: HGV RNA was detected in 4 of 45 patients with a diagnosis of non-A-E hepatitis (9 percent), 23 of 116 patients with hepatitis C (20 percent), 25 of 100 patients with hepatitis A (25 percent), and 32 of 100 patients with hepatitis B (32 percent) (P<0.05 for the comparison of hepatitis B with hepatitis non-A-E or C). The clinical characteristics of the acute illness were similar for patients with HGV alone and those with hepatitis A, B, or C with or without HGV infection. During a follow-up period of one to nine years, chronic hepatitis did not develop in any of the patients with HGV alone, but 75 percent were persistently positive for HGV RNA, as were 87 percent of those with both hepatitis C and HGV infection. The rates of chronic hepatitis were similar in patients with hepatitis C alone (60 percent) and those with both hepatitis C and HGV infection (61 percent). CONCLUSIONS: The evidence from this surveillance study does not implicate HGV as an etiologic agent of non-A-E hepatitis. Persistent infection with HGV was common, but it did not lead to chronic disease and did not affect the clinical course in patients with hepatitis A, B, or C.
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Cites
The Natural History of Community-Acquired Hepatitis C in the United States
Alter, M. J., Margolis, H. S., Krawczynski, K., Judson, F. N., Mares, A., Alexander, W. J., Hu, P. Y., Miller, J. K., Gerber, M. A., Sampliner, R. E., et al. (1992) · New England Journal of Medicine · doi:10.1056/nejm199212313272702 · Cited by 1,592
Self-citationMolecular Cloning and Disease Association of Hepatitis G Virus: A Transfusion-Transmissible Agent
Linnen, J., Wages, J., Zhang-Keck, Z.-Y., Fry, K. E., Krawczynski, K. Z., Alter, H., Koonin, E., Gallagher, M., Alter, M., Hadziyannis, S., et al. (1996) · Science · doi:10.1126/science.271.5248.505 · Cited by 1,359
Self-citationIsolation of novel virus-like sequences associated with human hepatitis
Simons, J. N., Leary, T. P., Dawson, G. J., Pilot-Matias, T. J., Muerhoff, A. S., Schlauder, G. G., Desai, S. M., & Mushahwar, I. K. (1995) · Nature Medicine · doi:10.1038/nm0695-564 · Cited by 1,129
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Self-citationAlter, H. J., Nakatsuji, Y., Melpolder, J., Wages, J., Wesley, R., Shih, J. W.-K., & Kim, J. P. (1997) · New England Journal of Medicine · doi:10.1056/nejm199703133361102 · Cited by 579
Self-citationAach, R. D., Stevens, C. E., Hollinger, F. B., Mosley, J. W., Peterson, D. A., Taylor, P. E., Johnson, R. G., Barbosa, L. H., & Nemo, G. J. (1991) · New England Journal of Medicine · doi:10.1056/nejm199111073251901 · Cited by 523
Alter, M. J. (1990) · JAMA · doi:10.1001/jama.263.9.1218 · Cited by 458
Self-citationImportance of Heterosexual Activity in the Transmission of Hepatitis B and Non-A, Non-B Hepatitis
Alter, M. J. (1989) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.1989.03430090063034 · Cited by 435
Self-citationFiordalisi, G., Zanella, I., Mantero, G., Bettinardi, A., Stellini, R., Paraninfo, G., Cadeo, G., & Primi, D. (1996) · Journal of Infectious Diseases · doi:10.1093/infdis/174.1.181 · Cited by 162
Hepatitis C virus antigen in hepatocytes: Immunomorphologic detection and identification
Krawczyński, K., Beach, M. J., Bradley, D. W., Kuo, G., Bisceglie, A. M. D., Houghton, M., Reyes, G. R., Kim, J. P., Choo, Q.-L., & Alter, M. J. (1992) · Gastroenterology · doi:10.1016/0016-5085(92)90856-t · Cited by 151
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Cited by
Orland, J. R., Wright, T. L., & Cooper, S. (2001) · Hepatology · doi:10.1053/jhep.2001.22112 · Cited by 196
Chu, C. M., Lin, S., Hsieh, S., Yeh, C., Lin, D., Sheen, I., & Liaw, Y. (1999) · Journal of Medical Virology · doi:10.1002/(sici)1096-9071(199906)58:2<154::aid-jmv9>3.0.co;2-e · Cited by 32
Metadata
- Authors
- Alter, M. J., Gallagher, M., Morris, T. T., Moyer, L. A., Meeks, E. L., Krawczynski, K., Kim, J. P., & Margolis, H. S.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1997-03-13
- Volume
- 336
- Issue
- 11
- Pages
- 741-746
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2328399749
- Cited by
- 409
- References
- 12
- FWCI
- 51.27
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Alter, M. J., Gallagher, M., Morris, T. T., Moyer, L. A., Meeks, E. L., Krawczynski, K., Kim, J. P., & Margolis, H. S. (1997). Acute Non-A–E Hepatitis in the United States and the Role of Hepatitis G Virus Infection. New England Journal of Medicine. https://doi.org/10.1056/nejm199703133361101
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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