The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.
Outcome of Cord-Blood Transplantation from Related and Unrelated Donors
Open accessAbstract
BACKGROUND: Cord-blood banks have increased the use of cord-blood transplantation in patients with hematologic disorders. We have established a registry containing information on the outcome of cord-blood transplantation. METHODS: We sent questionnaires to 45 transplantation centers for information on patients receiving cord-blood transplants from 1988 to 1996. Reports on 143 transplantations, performed at 45 centers, were studied, and the responses were analyzed separately according to whether the donor was related or unrelated to the recipient. RESULTS: Among 78 recipients of cord blood from related donors, the Kaplan-Meier estimate of survival at one year was 63 percent. Younger age, lower weight, transplants from HLA-identical donors, and cytomegalovirus-negative serologic results in the recipient were favorable prognostic factors. Graft-versus-host-disease of at least grade II occurred at estimated rates of 9 percent in 60 recipients of HLA-matched cord blood and 50 percent in 18 recipients of HLA-mismatched cord blood. Neutrophil engraftment was associated with an age of less than six years (P = 0.02) and a weight of less than 20 kg (P = 0.02), and it occurred in 85 percent of patients receiving 37 million or more nucleated cells per kilogram of body weight. Among 65 patients who received cord blood from unrelated donors, the Kaplan-Meier estimate of survival at one year was 29 percent. Cytomegalovirus-negative serologic status in these recipients was associated with improved survival (P = 0.03) and was the most important predictor of graft-versus-host disease (P = 0.04). Neutrophil recovery occurred in 94 percent of the patients who received 37 million or more nucleated cells per kilogram from unrelated donors. CONCLUSIONS: Cord blood is a feasible alternative source of hematopoietic stem cells for pediatric and some adult patients with major hematologic disorders, particularly if the donor and the recipient are related.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
GLUCKSBERG, H., STORB, R., FEFER, A., BUCKNER, C. D., NEIMAN, P. E., CLIFT, R. A., LERNER, K. G., & THOMAS, E. D. (1974) · Transplantation · doi:10.1097/00007890-197410000-00001 · Cited by 3,694
Gluckman, E., Broxmeyer, H. E., Auerbach, A. D., Friedman, H. S., Douglas, G. W., Devergie, A., Esperou, H., Thierry, D., Socie, G., Lehn, P., et al. (1989) · New England Journal of Medicine · doi:10.1056/nejm198910263211707 · Cited by 2,094
Self-citationBroxmeyer, H. E., Douglas, G. W., Hangoc, G., Cooper, S., Bard, J., English, D., Arny, M., Thomas, L., & Boyse, E. A. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.10.3828 · Cited by 1,201
Evidence for a mitotic clock in human hematopoietic stem cells: loss of telomeric DNA with age.
Vaziri, H., Dragowska, W., Allsopp, R. C., Thomas, T. E., Harley, C. B., & Lansdorp, P. M. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.21.9857 · Cited by 1,132
Kurtzberg, J., Laughlin, M., Graham, M. L., Smith, C., Olson, J. F., Halperin, E. C., Ciocci, G., Carrier, C., Stevens, C. E., & Rubinstein, P. (1996) · New England Journal of Medicine · doi:10.1056/nejm199607183350303 · Cited by 1,024
The aging of hematopoietic stem cells
Morrison, S. J., Wandycz, A. M., Akashi, K., Globerson, A., & Weissman, I. L. (1996) · Nature Medicine · doi:10.1038/nm0996-1011 · Cited by 853
Rubinstein, P., Dobrila, L., Rosenfield, R. E., Adamson, J. W., Migliaccio, G., Migliaccio, A. R., Taylor, P. E., & Stevens, C. E. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.22.10119 · Cited by 819
Wagner, J., Rosenthal, J., Sweetman, R., Shu, X., Davies, S., Ramsay, N., McGlave, P., Sender, L., & Cairo, M. (1996) · Blood · doi:10.1182/blood.v88.3.795.795 · Cited by 629
Wagner, J., Steinbuch, M., Kernan, N., Broxmayer, H., & Gluckman, E. (1995) · The Lancet · doi:10.1016/s0140-6736(95)91268-1 · Cited by 587
Self-citationBroxmeyer, H. E., Hangoc, G., Cooper, S., Ribeiro, R. C., Graves, V, Yoder, M., Wagner, J., Vadhan-Raj, S., Benninger, L., & Rubinstein, P. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.9.4109 · Cited by 490
Cited by
Isolation of multipotent mesenchymal stem cells from umbilical cord blood
Lee, O. K., Kuo, T. K., Chen, W.-M., Lee, K.-D., Hsieh, S.-L., & Chen, T.-H. (2004) · Blood · doi:10.1182/blood-2003-05-1670 · Cited by 1,360
Umbilical cord blood transplantation: the first 25 years and beyond
Ballen, K. K., Gluckman, E., & Broxmeyer, H. E. (2013) · Blood · doi:10.1182/blood-2013-02-453175 · Cited by 709
Self-citationLong-Term Survival and Late Deaths after Allogeneic Bone Marrow Transplantation
Socié, G., Stone, J. V., Wingard, J. R., Weisdorf, D., Henslee-Downey, P. J., Bredeson, C., Cahn, J.-Y., Passweg, J. R., Rowlings, P. A., Schouten, H. C., et al. (1999) · New England Journal of Medicine · doi:10.1056/nejm199907013410103 · Cited by 698
The rate of telomere sequence loss in human leukocytes varies with age
Frenck, R. W., Blackburn, E. H., & Shannon, K. M. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.10.5607 · Cited by 675
Guidelines for the diagnosis and management of aplastic anaemia
Marsh, J. C. W., Ball, S. E., Cavenagh, J., Darbyshire, P., Dokal, I., Gordon‐Smith, E. C., Keidan, J., Laurie, A., Martin, A., Mercieca, J., et al. (2009) · British Journal of Haematology · doi:10.1111/j.1365-2141.2009.07842.x · Cited by 560
Metadata
- Authors
- Gluckman, E., Rocha, V., Boyer-Chammard, A., Locatelli, F., Arcese, W., Pasquini, R., Ortega, J., Souillet, G., Ferreira, E., Laporte, J.-P., Fernandez, M., & Chastang, C.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1997-08-07
- Volume
- 337
- Issue
- 6
- Pages
- 373-381
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2330713242
- Cited by
- 1,249
- References
- 14
- FWCI
- 37.22
- Type
- journal article
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Outcome of Cord-Blood Transplantation from Related and Unrelated Donors. https://app.cochat.ai/papers/10.1056/nejm199708073370602
- The paper
- Gluckman, E., Rocha, V., Boyer-Chammard, A., Locatelli, F., Arcese, W., Pasquini, R., Ortega, J., Souillet, G., Ferreira, E., Laporte, J.-P., Fernandez, M., & Chastang, C. (1997). Outcome of Cord-Blood Transplantation from Related and Unrelated Donors. New England Journal of Medicine. https://doi.org/10.1056/nejm199708073370602
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
