The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Management of Life-Threatening Acid–Base Disorders
Abstract
Adverse Consequences of Severe AlkalemiaSevere alkalemia (blood pH greater than 7.60) can compromise cerebral and myocardial perfusion by causing arteriolar constriction, an effect that is more pronounced in respiratory than in metabolic alkalosis (Table 2).6971 Neurologic abnormalities may ensue, including headache, tetany, seizures, lethargy, delirium, and stupor. The associated reduction in the plasma concentration of ionized calcium probably contributes to these manifestations. Although it exerts a moderate positive inotropic effect on the isolated heart, alkalemia reduces the anginal threshold and predisposes the patient to refractory supraventricular and ventricular arrhythmias. This arrhythmogenic action is more pronounced in patients with . . .
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Amato, M. B., Barbas, C. S., Medeiros, D. M., Schettino, G. D. P., Lorenzi Filho, G., Kairalla, R. A., Deheinzelin, D., Morais, C., Fernandes, E. D. O., & Takagaki, T. Y. (1995) · American journal of respiratory and critical care medicine · doi:10.1164/ajrccm.152.6.8520744 · Cited by 625
Cooper, D. J., Walley, K. R., Wiggs, B. R., & Russell, J. A. (1990) · Annals of Internal Medicine · doi:10.7326/0003-4819-112-7-492 · Cited by 452
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Laffey, J. G., & Kavanagh, B. P. (2002) · New England Journal of Medicine · doi:10.1056/nejmra012457 · Cited by 391
Sodium Bicarbonate for the Treatment of Lactic Acidosis
Forsythe, S. M., & Schmidt, G. A. (2000) · Chest · doi:10.1378/chest.117.1.260 · Cited by 340
Hypocapnia and the injured brain: More harm than benefit
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Metadata
- Authors
- Adrogué, H. J., & Madias, N. E.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1998-01-08
- Volume
- 338
- Issue
- 2
- Pages
- 107-111
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2313287572
- Cited by
- 405
- References
- 2
- FWCI
- 14.34
- Type
- journal article
- Language
- en
- Open access
- closed
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