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Infection in Organ-Transplant Recipients
Abstract
A primary goal in organ transplantation is the prevention or effective treatment of infection, the most common life-threatening complication of long-term immunosuppressive therapy. The challenges involved in achieving this goal are several: a broad range of potential sources of infection ranging from latent viruses to pathogens of both community and hospital origin; immunosuppression-induced impairment of the inflammatory response, which attenuates the signs and symptoms of invasive infection; and the adverse effects of the antimicrobial drugs used for prophylaxis and therapy, which result both from the duration of therapy required and from interactions with the immunosuppressive drugs cyclosporine and tacrolimus. Our . . .
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Cited by
Qu, J., Zhao, X., Ma, P. X., & Guo, B. (2018) · Acta Biomaterialia · doi:10.1016/j.actbio.2018.03.018 · Cited by 468
Transplantation of Anergic Histoincompatible Bone Marrow Allografts
Guinan, E. C., Boussiotis, V. A., Neuberg, D., Brennan, L. L., Hirano, N., Nadler, L. M., & Gribben, J. G. (1999) · New England Journal of Medicine · doi:10.1056/nejm199906033402202 · Cited by 429
Edwards, Jr., Bodey, G. P., Bowden, R. A., Buchner, T., de Pauw, B. E., Filler, S. G., Ghannoum, M. A., Glauser, M., Herbrecht, R., Kauffman, C. A., et al. (1997) · Clinical Infectious Diseases · doi:10.1086/514504 · Cited by 418
Self-citationvan Delden, C., Stampf, S., Hirsch, H. H., Manuel, O., Meylan, P., Cusini, A., Hirzel, C., Khanna, N., Weisser, M., Garzoni, C., et al. (2020) · Clinical Infectious Diseases · doi:10.1093/cid/ciz1113 · Cited by 319
Metadata
- Authors
- Fishman, J. A., & Rubin, R. H.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1998-06-11
- Volume
- 338
- Issue
- 24
- Pages
- 1741-1751
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2332401864
- Cited by
- 1,622
- References
- 0
- FWCI
- 64.00
- Type
- journal article
- Language
- en
- Open access
- closed
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- Fishman, J. A., & Rubin, R. H. (1998). Infection in Organ-Transplant Recipients. New England Journal of Medicine. https://doi.org/10.1056/nejm199806113382407
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