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Acute Lymphoblastic Leukemia
Abstract
Acute lymphoblastic leukemia (ALL) is diagnosed in 3000 to 4000 persons in the United States each year; two thirds of them are children.1,2 The current rate of cure of nearly 80 percent in children attests to remarkable progress in the development of effective treatments for resistant subtypes of the disease. Progress has been incremental, from the introduction of combination chemotherapy and central nervous system treatment for presymptomatic leukemia to newer, intensive treatment regimens for patients at high risk for relapse (Figure 1). In contrast, only 30 to 40 percent of adults with ALL are cured.2,3 This discrepancy can . . .
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Cited by
Golub, T. R., Slonim, D. K., Tamayo, P., Huard, C., Gaasenbeek, M., Mesirov, J. P., Coller, H., Loh, M. L., Downing, J. R., Caligiuri, M. A., et al. (1999) · Science · doi:10.1126/science.286.5439.531 · Cited by 11,516
Pui, C.-H., Robison, L. L., & Look, A. T. (2008) · The Lancet · doi:10.1016/s0140-6736(08)60457-2 · Cited by 1,564
Self-citationTreating Childhood Acute Lymphoblastic Leukemia without Cranial Irradiation
Pui, C.-H., Campana, D., Pei, D., Bowman, W. P., Sandlund, J. T., Kaste, S. C., Ribeiro, R. C., Rubnitz, J. E., Raimondi, S. C., Onciu, M., et al. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0900386 · Cited by 1,215
Self-citationPui, C.-H., Mahmoud, H. H., Wiley, J. M., Woods, G. M., Leverger, G., Camitta, B., Hastings, C., Blaney, S. M., Relling, M. V., & Reaman, G. H. (2001) · Journal of Clinical Oncology · doi:10.1200/jco.2001.19.3.697 · Cited by 361
Self-citationRacial and ethnic differences in survival of children with acute lymphoblastic leukemia
Bhatia, S., Sather, H. N., Heerema, N. A., Trigg, M. E., Gaynon, P. S., & Robison, L. L. (2002) · Blood · doi:10.1182/blood-2002-02-0395 · Cited by 270
Metadata
- Authors
- Pui, C.-H., & Evans, W. E.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1998-08-27
- Volume
- 339
- Issue
- 9
- Pages
- 605-615
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W4242108431
- Cited by
- 832
- References
- 0
- FWCI
- 57.77
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Acute Lymphoblastic Leukemia. https://app.cochat.ai/papers/10.1056/nejm199808273390907
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- Pui, C.-H., & Evans, W. E. (1998). Acute Lymphoblastic Leukemia. New England Journal of Medicine. https://doi.org/10.1056/nejm199808273390907
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
