The DOI matches its Crossref record; 53 of the 53 references it cites were found in a registry or an index.
Passive smoking and the risk of coronary heart disease—a meta-analysis of epidemiologic studies
Open accessAbstract
BACKGROUND: The effect of passive smoking on the risk of coronary heart disease is controversial. We conducted a meta-analysis of the risk of coronary heart disease associated with passive smoking among nonsmokers. METHODS: We searched the Medline and Dissertation Abstracts Online data bases and reviewed citations in relevant articles to identify 18 epidemiologic (10 cohort and 8 case-control) studies that met prestated inclusion criteria. Information on the designs of the studies, the characteristics of the study subjects, exposure and outcome measures, control for potential confounding factors, and risk estimates was abstracted independently by three investigators using a standardized protocol. RESULTS: Overall, nonsmokers exposed to environmental smoke had a relative risk of coronary heart disease of 1.25 (95 percent confidence interval, 1.17 to 1.32) as compared with nonsmokers not exposed to smoke. Passive smoking was consistently associated with an increased relative risk of coronary heart disease in cohort studies (relative risk, 1.21; 95 percent confidence interval, 1.14 to 1.30), in case-control studies (relative risk, 1.51; 95 percent confidence interval, 1.26 to 1.81), in men (relative risk, 1.22; 95 percent confidence interval, 1.10 to 1.35), in women (relative risk, 1.24; 95 percent confidence interval, 1.15 to 1.34), and in those exposed to smoking at home (relative risk, 1.17; 95 percent confidence interval, 1.11 to 1.24) or in the workplace (relative risk, 1.11; 95 percent confidence interval, 1.00 to 1.23). A significant dose-response relation was identified, with respective relative risks of 1.23 and 1.31 for nonsmokers who were exposed to the smoke of 1 to 19 cigarettes per day and those who were exposed to the smoke of 20 or more cigarettes per day, as compared with nonsmokers not exposed to smoke (P=0.006 for linear trend). CONCLUSIONS: Passive smoking is associated with a small increase in the risk of coronary heart disease. Given the high prevalence of cigarette smoking, the public health consequences of passive smoking with regard to coronary heart disease may be important.
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“Previous studies have found different effect sizes for SHS exposure at home and at work442,443,462, a factor that was not investigated in our analysis.”
From Health effects associated with exposure to secondhand smoke: a Burden of Proof study (2024) · cites this paper as [442]
In the citing paper
“Accumulated evidence shows that passive smoking increases the risk of CHD, with a higher relative risk than might be expected.209,224,225”
From European Guidelines on cardiovascular disease prevention in clinical practice (version 2012) (2012) · cites this paper as [209]
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Cites
Meta-analysis in clinical trials
DerSimonian, R., & Laird, N. (1986) · Controlled Clinical Trials · doi:10.1016/0197-2456(86)90046-2 · Cited by 39,552
Mortality in relation to smoking: 40 years' observations on male British doctors
Doll, R., Peto, R., Wheatley, K., Gray, R., & Sutherland, I. (1994) · BMJ · doi:10.1136/bmj.309.6959.901 · Cited by 5,932
(1994) · New England Journal of Medicine · doi:10.1056/nejm199404143301501 · Cited by 4,737
The Handbook of Research Synthesis.
Howel, D., Cooper, H., & Hedges, L. V. (1995) · Biometrics · doi:10.2307/2533295 · Cited by 3,657
Hennekens, C. H., Buring, J. E., Manson, J. E., Stampfer, M., Rosner, B., Cook, N. R., Belanger, C., LaMotte, F., Gaziano, J. M., Ridker, P. M., et al. (1996) · New England Journal of Medicine · doi:10.1056/nejm199605023341801 · Cited by 2,397
Mortality in relation to smoking : 40 years' observations on male British doctors
Doll, H. (1994) · Medical Entomology and Zoology · Cited by 1,417
Statistical Methods in Epidemiology
(2012) · Springer eBooks · doi:10.1007/springerreference_205629 · Cited by 1,123
Pirkle, J. L. (1996) · JAMA · doi:10.1001/jama.275.16.1233 · Cited by 707
Passive smoking and heart disease. Epidemiology, physiology, and biochemistry.
Glantz, S. A., & Parmley, W. W. (1991) · Circulation · doi:10.1161/01.cir.83.1.1 · Cited by 683
Environmental tobacco smoke exposure and ischaemic heart disease: an evaluation of the evidence
Law, M. R., Morris, J. K., & Wald, N. J. (1997) · BMJ · doi:10.1136/bmj.315.7114.973 · Cited by 604
Research works printed but not linked: 5
- 1993, MMWR Morb Mortal Wkly Rep, 42, 645
- Hirayama T, 1990, N Z Med J, 103, 54
- Butler TL. The relationship of passive smoking to various health outcomes among Seventh-day Adventists in California. (Doctoral dissertation. Los Angeles: University of California, 1988.)
- He Y, 1989, Chung Hua Yu Fang I Hsueh Tsa Chih, 23, 19
- Khalfen ES, 1987, Ter Arkh, 59, 112
Cited by
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Items 601–613 of 613
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俊明, 海. (2011) · Journal of JCS Cardiologists · doi:10.1253/jjcsc.19.2_330
1.世界で広まる法的喫煙規制とその効果(Smoking banの実態とその効果:心臓発作は著減する,第8回禁煙推進セミナー)
真美, 飯. (2009) · Journal of JCS Cardiologists · doi:10.1253/jjcsc.17.2_341
4. 受動喫煙防止条例と急性冠症候群(受動喫煙防止条例を全国で実施するには,第11回禁煙推進セミナー)
海老名, 俊. (2012) · Journal of JCS Cardiologists · doi:10.1253/jjcsc.20.2_364
Yang, Y., 彭年春, Chen, G., Wan, Q., Yan, L., Wang, G., Qin, Y., Luo, Z., Tang, X., Huo, Y., et al. (2022) · Figshare · doi:10.6084/m9.figshare.19029174
Awareness regarding the effect of passive smoking among adults: a cross-sectional study
Kkunnil, S. P., Pradeep, S., Shankar, V., Sujith, S. K. C., Sreelakshmi, T., Cheriyakandi, S. V., Kandiyil, T. A., Purayil, S. P., Puthukkudy, V. N., Mangi, T., et al. (2026) · International Journal of Community Medicine and Public Health · doi:10.18203/2394-6040.ijcmph20260691
Patient Selection for Cardiac Transplantation
Cronley, A. C., Craig, M. L., & Bakel, A. B. V. (2026) · Springer eBooks · doi:10.1007/978-3-032-12629-0_1
Le risque cardiovasculaire : l'environnement de diffusion des facteurs de risque modifiables
Bennia, F. (2015) · theses.fr (ABES) · doi:10.70675/999c757cza445z4871zb4bczfe34a83d8866
Cui, L., Han, S., Yu, P., Miao, R., Cun, X., Zhang, Y., Ren, P., Feng, P., Song, L., Fu, Y., et al. (2026) · Archives of Toxicology · doi:10.1007/s00204-026-04405-z
“Furthermore, an increasing amount of evidence indicates that exposure to second-hand smoke (SHS) is also a risk factor, closely related to coronary heart disease, stroke, and other conditions (He et al. 1999).”
Sergeev, A. S., & Дыдышко, В. Т. (2026) · Новые Санкт-Петербургские врачебные ведомости. · doi:10.24884/1609-2201-2026-105-2-67-70
“Для всех курящих в связи с доказанным негативным эффектом курения на смертность рекомен-дуется полный отказ от курения (ОК) [2], что сопровождается достоверным улучшением кардиоваскулярного прогноза относительно субъектов, продолжающих курить [3], однако для лиц со сниженной мотивацией возможно…”
Can Smoking Cessation Slow the Rate of Decline in FEV1/FVC(%) Seen in Smokers?
Moriuchi, T., Matsui, H., Matsuda, Y., Nishi, K., & Kanamoto, I. (2005) · Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences) · doi:10.5649/jjphcs.31.173
Cardiovascular disease among diabetic women with bilateral oophorectomy.
Appiah, D. (2013) · ThinkIR: The University of Louisville's Institutional Repository (University of Louisville) · doi:10.18297/etd/43
Rauchen - ein verkannter Risikofaktor für die Progredienz primärer und sekundärer Nierenkrankheiten
Orth, & Ritz, E. (2000) · Journal für Kardiologie (Krause & Pachernegg GmbH)
Ruíz, D. L. M., & Bruno, G. (2013) · renati
Metadata
- Authors
- He, J., Vupputuri, S., Allen, K., Prerost, M. R., Hughes, J., & Whelton, P. K.
- Affiliations
- Tulane University (US)
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1999-03-25
- Volume
- 340
- Issue
- 12
- Pages
- 920-926
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2316007655
- Cited by
- 616
- References
- 51
- Citations by year
- 2026: 4 · 2025: 6 · 2024: 8 · 2023: 6 · 2022: 9 · 2021: 8 · 2020: 9 · 2019: 22 · 2018: 21 · 2017: 39 · 2016: 21 · 2015: 25 · 2014: 26 · 2013: 41 · 2012: 31
- FWCI
- 3.43
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (1p20es006435-01, 5r01hl060300-05)
- National Heart, Lung, and Blood Institute (HL60300)
- National Institute of Environmental Health Sciences (ES06435)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Smoking Behavior and Cessation
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
- Keywords
- passive smoking, environmental tobacco smoke, coronary artery disease, non-smokers, cardiovascular risk, dose-response relationship, sex differences
- MeSH terms
- Coronary Disease, Environmental Exposure, Female, Humans, Male, Risk, Risk Factors, Tobacco Smoke Pollution, Epidemiologic Studies
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