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Cited by 1,592

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Hyponatremia

Adrogué, Horacio J., Madias, Nicolaos E.·2000·New England Journal of Medicine

Abstract

Hyponatremia is defined as a decrease in the serum sodium concentration to a level below 136 mmol per liter. Whereas hypernatremia always denotes hypertonicity, hyponatremia can be associated with low, normal, or high tonicity.1,2 Effective osmolality or tonicity refers to the contribution to osmolality of solutes, such as sodium and glucose, that cannot move freely across cell membranes, thereby inducing transcellular shifts in water.3 Dilutional hyponatremia, by far the most common form of the disorder, is caused by water retention. If water intake exceeds the capacity of the kidneys to excrete water, dilution of body solutes results, causing hypo-osmolality . . .

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Crossref · 10.1056/nejm200005253422107

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Metadata

Authors
Adrogué, H. J., & Madias, N. E.
Venue
New England Journal of Medicine
Published
2000-05-25
Volume
342
Issue
21
Pages
1581-1589
ISSN
  • 0028-4793 (ISSN-L)
  • 1533-4406
OpenAlex
W4254729059
Cited by
1,592
References
1
FWCI
25.47
Type
journal article
Language
en
Open access
closed

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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