Long-Term Leptin-Replacement Therapy for Lipoatrophic Diabetes
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correspondence 615 and Decherd do not provide robust outcome data on the procedures they advocate.I consider an average fee of more than $5,000 for an operation lasting several hours to be expensive and profitable. 1 The experience of a mystery shopper who consulted five established plastic surgeons with the same requests illustrates the lack of consensus among cosmetic surgeons about optimal therapy. 2 Both the recommended treatments and their costs ($2,900 to $14,150) varied greatly among the surgeons.Given the lack of good studies quantifying the benefits and risks of many of the cosmetic procedures and products that leading plastic sur-geons now advocate and sell, and given the even scantier information on individual surgeons' outcomes, I hope the American Society of Plastic Surgeons will take a leading role in filling this void in the data.
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“Despite these limitations, our observations have been supported by a recent report from Japan (14).”
From Long-Term Efficacy of Leptin Replacement in Patients With Generalized Lipodystrophy (2005) · cites this paper as [14]
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Leptin-Replacement Therapy for Lipodystrophy
Oral, E. A., Simha, V., Ruiz, E., Andewelt, A., Premkumar, A., Snell, P., Wagner, A. J., DePaoli, A. M., Reitman, M. L., Taylor, S. I., et al. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa012437 · Cited by 1,247 · see citing works
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Brennan, A. M., & Mantzoros, C. S. (2006) · Nature Clinical Practice Endocrinology & Metabolism · doi:10.1038/ncpendmet0196 · Cited by 374 · see citing works
Long-Term Efficacy of Leptin Replacement in Patients With Generalized Lipodystrophy
Javor, E. D., Cochran, E. K., Musso, C., Young, J. R., DePaoli, A. M., & Gorden, P. (2005) · Diabetes · doi:10.2337/diabetes.54.7.1994 · Cited by 226 · see citing works
- Authors
- Ebihara, K., Masuzaki, H., & Nakao, K.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2004-08-05
- Volume
- 351
- Issue
- 6
- Pages
- 615-616
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W1964092078
- Cited by
- 48
- References
- 1
- Citations by year
- 2025: 2 · 2023: 2 · 2022: 1 · 2020: 1 · 2019: 2 · 2018: 1 · 2017: 2 · 2015: 3 · 2014: 3 · 2013: 5 · 2012: 5
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
- Health Sciences › Medicine › Surgery › Bariatric Surgery and Outcomes
- Keywords
- leptin replacement therapy, lipoatrophic diabetes, lipodystrophy, long-term treatment outcomes, cosmetic surgery, plastic surgeons, surgeon fees, treatment costs, American Society of Plastic Surgeons
- MeSH terms
- Adult, Child, Diabetes Mellitus, Lipoatrophic, Female, Glycated Hemoglobin, Humans, Liver, Male, Triglycerides, Hypertriglyceridemia, Leptin
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