Hypothyroidism due to ethionamide
Abstract
To the Editor: Ethionamide (Trecator-SC, Wyeth-Ayerst) is an antimycobacterial drug used as a second-line agent in the treatment of multidrug-resistant tuberculosis. It is structurally similar to m...
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Hypothyroid HAART-treated patients needing increased L-T4 doses were reported with ritonavir, abacavir-lamivudine and lopinavir-ritonavir, and lopinavir/ritonavir plus zidovudine and lamivudine.
“Hypothyroid HAART-treated patients needing increased L-T4 doses were reported (53–55). HAART drugs were ritonavir (48), abacavir–lamivudine and lopinavir–ritonavir (54), and lopinavir/ritonavir plus zidovudine and lamivudine (55).”
From L-T4 therapy in the presence of pharmacological interferents (2020) · cites this paper as [48]
Cites
Tuberculosis Drug Resistance: A Global Threat
Nachega, J. B., & Chaisson, R. E. (2003) · Clinical Infectious Diseases · doi:10.1086/344657 · Cited by 225 · see citing works
Disorders of the thyroid gland
Balasubramanian, S. P., & Smith, D. (2015) · CRC Press eBooks · doi:10.1201/b17820-23 · Cited by 217 · see citing works
Ethionamide-lnduced Goitrous Hypothyroidism
Drucker, D. J., EGGO, M. C., SALIT, I. E., & BURROW, G. N. (1984) · Annals of Internal Medicine · doi:10.7326/0003-4819-100-6-837 · Cited by 40 · see citing works
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Andries, A., Isaakidis, P., Das, M., Khan, S., Paryani, R., Desai, C., Dalal, A., Mansoor, H., Verma, R., Fernandes, D., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0078313 · Cited by 27 · see citing works
“In rare cases, hypothyroidism can manifest severely as cardiac disease and development of a pericardial effusion[18].”
BackgroundL-T4 therapy in the presence of pharmacological interferents
Benvenga, S. (2020) · Frontiers in Endocrinology · doi:10.3389/fendo.2020.607446 · Cited by 13 · see citing works
“HAART drugs were ritonavir (48), abacavir– lamivudine and lopinavir–ritonavir (54), and lopinavir/ritonavir plus zidovudine and lamivudine (55).”
Background
- Authors
- McDonnell, M. E., Braverman, L. E., & Bernardo, J.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2005-06-30
- Volume
- 352
- Issue
- 26
- Pages
- 2757-2759
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2026637351
- Cited by
- 27
- References
- 3
- Citations by year
- 2025: 1 · 2022: 1 · 2020: 2 · 2019: 1 · 2018: 1 · 2017: 3 · 2016: 1 · 2015: 3 · 2014: 1 · 2013: 1
- FWCI
- 1.04
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Disorders and Treatments
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
- Health Sciences › Medicine › Infectious Diseases › Tuberculosis Research and Epidemiology
- Keywords
- ethionamide, hypothyroidism, drug-induced thyroid dysfunction, multidrug-resistant tuberculosis, adverse drug reactions
- MeSH terms
- Antitubercular Agents, Ethionamide, Female, Humans, Hypothyroidism, Middle Aged, Tuberculosis, Multidrug-Resistant
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