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Pregnancy after Transplantation of Cryopreserved Ovarian Tissue in a Patient with Ovarian Failure after Chemotherapy
Open accessAbstract
To the Editor: Premenopausal women who undergo high-dose chemotherapy have a very high risk of ovarian failure.1 Cryopreservation of ovarian tissue with subsequent autotransplantation has effectively preserved fertility in an animal model,2 but its efficacy in humans has been uncertain. Eggs that were aspirated from cryopreserved ovarian tissue transplanted in heterotopic sites did not result in a pregnancy.3 A live birth was reported after transplantation of cryopreserved ovarian tissue in a woman who had undergone treatment for Hodgkin's disease; however, since the woman had ovulated before transplantation, it is uncertain whether the egg came from the native ovary or the . . .
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Citations
Cited by
(2019) · Fertility and Sterility · doi:10.1016/j.fertnstert.2019.09.013 · Cited by 753
Children born after autotransplantation of cryopreserved ovarian tissue. A review of 13 live births
Donnez, J., Silber, S., Andersen, C. Y., Demeestere, I., Piver, P., Meirow, D., Pellicer, A., & Dolmans, M.-M. (2011) · Annals of Medicine · doi:10.3109/07853890.2010.546807 · Cited by 342
Self-citationFertility Preservation in Adolescents and Young Adults With Cancer
Levine, J., Canada, A., & Stern, C. J. (2010) · Journal of Clinical Oncology · doi:10.1200/jco.2009.22.8312 · Cited by 323
Gellert, S. E., Pors, S. E., Kristensen, S. G., Bay-Bjørn, A. M., Ernst, E., & Yding Andersen, C. (2018) · Journal of Assisted Reproduction and Genetics · doi:10.1007/s10815-018-1144-2 · Cited by 282
Birgit, B., Julius, H., Carsten, R., Maryam, S., Gabriel, F., Victoria, K., Margareta, F., & Outi, H. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2008-0708 · Cited by 254
Metadata
- Authors
- Meirow, D., Levron, J., Eldar-Geva, T., Hardan, I., Fridman, E., Zalel, Y., Schiff, E., & Dor, J.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2005-07-21
- Volume
- 353
- Issue
- 3
- Pages
- 318-321
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W1991238536
- Cited by
- 851
- References
- 0
- FWCI
- 69.87
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: Pregnancy after Transplantation of Cryopreserved Ovarian Tissue in a Patient with Ovarian Failure after Chemotherapy. https://app.cochat.ai/papers/10.1056/nejmc055237
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- Meirow, D., Levron, J., Eldar-Geva, T., Hardan, I., Fridman, E., Zalel, Y., Schiff, E., & Dor, J. (2005). Pregnancy after Transplantation of Cryopreserved Ovarian Tissue in a Patient with Ovarian Failure after Chemotherapy. New England Journal of Medicine. https://doi.org/10.1056/nejmc055237
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
