Investigation of a Researcher's Death Due to Septicemic Plague
Open accessAbstract
This letter identifies the death of a researcher from infection with disseminated Yersinia pestis, which he was working with in the lab. It was subsequently determined that he had hemochromatosis, a condition that may have increased his susceptibility to this infection.
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Infections with extracellular siderophilic pathogens can be lethal to HH patients.
“Considering that infections with extracellular siderophilic pathogens can be lethal to HH patients (Frank et al., 2011), these data highlight another possible application of hepcidin agonists.”
From Pharmacological Targeting of the Hepcidin/Ferroportin Axis (2016) · cites this paper as Frank et al., 2011
These data highlight another possible application of hepcidin agonists.
“Considering that infections with extracellular siderophilic pathogens can be lethal to HH patients (Frank et al., 2011), these data highlight another possible application of hepcidin agonists.”
From Pharmacological Targeting of the Hepcidin/Ferroportin Axis (2016) · cites this paper as Frank et al., 2011
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- Authors
- Frank, K. M., Schneewind, O., & Shieh, W.-J.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2011-06-30
- Volume
- 364
- Issue
- 26
- Pages
- 2563-2564
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2319134582
- Cited by
- 62
- References
- 4
- Citations by year
- 2026: 4 · 2025: 5 · 2024: 5 · 2023: 4 · 2022: 2 · 2021: 2 · 2020: 6 · 2019: 3 · 2018: 2 · 2017: 3 · 2016: 5 · 2015: 6 · 2014: 3 · 2013: 4 · 2012: 8
- FWCI
- 2.99
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Allergy and Infectious Diseases (U54AI057153)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Yersinia bacterium, plague, ectoparasites research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Bacillus and Francisella bacterial research
- Health Sciences › Medicine › Epidemiology › Fungal Infections and Studies
- Keywords
- Yersinia pestis, septicemic plague, laboratory-acquired infection, hemochromatosis, infection susceptibility, occupational exposure
- MeSH terms
- Autopsy, Ferritins, Hemochromatosis, Humans, Iron, Liver, Male, Middle Aged, Plague, Research Personnel, Yersinia pestis, Fatal Outcome
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