Goal-Directed Resuscitation in Septic Shock

Early goal-directed therapy in the treatment of severe sepsis and septic shock

Rivers, E., Nguyen, B., Havstad, S., Ressler, J., Muzzin, A., Knoblich, B., Peterson, E., & Tomlanovich, M. (2001) · New England Journal of Medicine · doi:10.1056/nejmoa010307 · Cited by 10,743 · see citing works

Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock

Kumar, A., Roberts, D., Wood, K. E., Light, B., Parrillo, J. E., Sharma, S., Suppes, R., Feinstein, D., Zanotti, S., Taiberg, L., et al. (2006) · Critical Care Medicine · doi:10.1097/01.ccm.0000217961.75225.e9 · Cited by 6,109 · see citing works

Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock

Dellinger, R. P., Carlet, J. M., Masur, H., Gerlach, H., Calandra, T., Cohen, J., Gea‐Banacloche, J., Keh, D., Marshall, J. C., Parker, M. M., et al. (2004) · Critical Care Medicine · doi:10.1097/01.ccm.0000117317.18092.e4 · Cited by 3,012 · see citing works

A randomized trial of protocol-based care for early septic shock.

The ProCESS Investigators (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1401602 · Cited by 2,414 · see citing works

Goal-Directed Resuscitation for Patients with Early Septic Shock

The ARISE Investigators and the ANZICS Clinical Trials Group (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1404380 · Cited by 2,023 · see citing works

Mortality Related to Severe Sepsis and Septic Shock Among Critically Ill Patients in Australia and New Zealand, 2000-2012

Kaukonen, K., Bailey, M., Suzuki, S., Pilcher, D. V., & Bellomo, R. (2014) · JAMA · doi:10.1001/jama.2014.2637 · Cited by 1,704 · see citing works

Physiological effects of hyperchloraemia and acidosis

Handy, J. M., & Soni, N. (2008) · British Journal of Anaesthesia · doi:10.1093/bja/aen148 · Cited by 189 · see citing works

Hyperchloremic Metabolic Acidosis Is a Predictable Consequence of Intraoperative Infusion of 0.9% Saline

Prough, D. S., & Bidani, A. (1999) · Anesthesiology · doi:10.1097/00000542-199905000-00003 · Cited by 180 · see citing works

Australasian resuscitation of sepsis evaluation (ARISE): A multi-centre, prospective, inception cohort study

Peake, S., Bailey, M., Bellomo, R., Cameron, P. A., Cross, A., Delaney, A. P., Finfer, S. R., Higgins, A. M., Jones, D. A., Myburgh, J., et al. (2009) · Resuscitation · doi:10.1016/j.resuscitation.2009.03.008 · Cited by 128 · see citing works

Protocol-Based Care for Early Septic Shock

Angus, D. C., Yealy, D. M., & Kellum, J. A. (2014) · New England Journal of Medicine · doi:10.1056/nejmc1406745 · Cited by 108 · see citing works

The Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock: 2008. An assessment by the Australian and New Zealand Intensive Care Society

Hicks, P. R., Cooper, D. J., Webb, S. A. R., Myburgh, J., Seppelt, I., Peake, S., Joyce, C., Stephens, D. P., Turner, A. J., French, C., et al. (2008) · Anaesthesia and Intensive Care · doi:10.1177/0310057x0803600202 · Cited by 36 · see citing works

The Importance of Intraoperative Hyperchloremia

Silva, J. M., Neves, E. F., Santana, T. C., Ferreira, U. P., Marti, Y. N., & Silva, J. M. C. (2009) · Brazilian Journal of Anesthesiology · doi:10.1590/s0034-70942009000300005 · Cited by 30 · see citing works

Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021

Evans, L., Rhodes, A., Alhazzani, W., Antonelli, M., Coopersmith, C. M., French, C., Machado, F. R., Mcintyre, L., Ostermann, M., Prescott, H. C., et al. (2021) · Intensive Care Medicine · doi:10.1007/s00134-021-06506-y · Cited by 5,082 · see citing works

Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021.

Evans, L., Rhodes, A., Alhazzani, W., Antonelli, M., Coopersmith, C. M., French, C., Machado, F. R., Mcintyre, L., Ostermann, M., Prescott, H. C., et al. (2021) · Critical Care Medicine · doi:10.1097/ccm.0000000000005337 · Cited by 2,935 · see citing works

Multicenter Implementation of a Treatment Bundle for Patients with Sepsis and Intermediate Lactate Values

Liu, V. X., Morehouse, J. W., Marelich, G. P., Soule, J., Russell, T., Skeath, M., Adams, C. L., Escobar, G. J., & Whippy, A. (2015) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201507-1489oc · Cited by 136 · see citing works

Perioperative goal-directed therapy and postoperative outcomes in patients undergoing high-risk abdominal surgery: a historical-prospective, comparative effectiveness study

Cannesson, M. P., Ramsingh, D. S., Rinehart, J. B., Demirjian, A. N., Vu, T. Q., Vakharia, S., Imagawa, D. K., Yu, Z., Greenfield, S., & Kain, Z. N. (2015) · Critical Care · doi:10.1186/s13054-015-0945-2 · Cited by 101 · see citing works

Early goal-directed therapy for severe sepsis and septic shock: A living systematic review

Simpson, S. Q., Gaines, M., Hussein, Y., & Badgett, R. G. (2016) · Journal of Critical Care · doi:10.1016/j.jcrc.2016.06.017 · Cited by 55 · see citing works

Barriers and facilitators towards implementing the Sepsis Six care bundle (BLISS-1): a mixed methods investigation using the theoretical domains framework

Roberts, N., Hooper, G., Lorencatto, F., Storr, W., & Spivey, M. (2017) · Scandinavian Journal of Trauma Resuscitation and Emergency Medicine · doi:10.1186/s13049-017-0437-2 · Cited by 52 · see citing works

Ebola virus disease complicated with viral interstitial pneumonia: a case report

INMI EBOV Team, Petrosillo, N., Nicastri, E., Lanini, S., Capobianchi, M. R., Di, A., Antonini, M., Puro, V., Lauria, F., Shindo, N., et al. (2015) · BMC Infectious Diseases · doi:10.1186/s12879-015-1169-4 · Cited by 48 · see citing works

Experiences of Ebola Survivors: Causes of Distress and Sources of Resilience

Schwerdtle, P. N., Clerck, V. D., & Plummer, V. (2017) · Prehospital and Disaster Medicine · doi:10.1017/s1049023x17000073 · Cited by 46 · see citing works

Modernising epidemic science: enabling patient-centred research during epidemics

Rojek, A. M., & Horby, P. (2016) · BMC Medicine · doi:10.1186/s12916-016-0760-x · Cited by 43 · see citing works

Advanced Hemodynamic Management in Patients with Septic Shock

Saugel, B., Huber, W., Nierhaus, A., Kluge, S., Reuter, D. A., & Wagner, J. Y. (2016) · BioMed Research International · doi:10.1155/2016/8268569 · Cited by 36 · see citing works

Challenging the One-hour Sepsis Bundle

Kalantari, A., & Rezaie, S. R. (2019) · Western Journal of Emergency Medicine · doi:10.5811/westjem.2018.11.39290 · Cited by 37 · see citing works

Quality of Life and 1-Year Survival in Patients With Early Septic Shock: Long-Term Follow-Up of the Australasian Resuscitation in Sepsis Evaluation Trial

Higgins, A. M., Peake, S., Bellomo, R., Cooper, D. J., Delaney, A. P., Harris, A., Howe, B. D., Nichol, A., Webb, S. A. R., & Williams, P. J. (2019) · Critical Care Medicine · doi:10.1097/ccm.0000000000003762 · Cited by 28 · see citing works

Contemporary hemodynamic monitoring, fluid responsiveness, volume optimization, and endpoints of resuscitation: an AAST critical care committee clinical consensus

Martin, N. D., Codner, P. A., Greene, W. R., Brasel, K. J., & Michetti, C. P. (2020) · Trauma Surgery & Acute Care Open · doi:10.1136/tsaco-2019-000411 · Cited by 24 · see citing works

Emergency Neurologic Life Support: Meningitis and Encephalitis

Gaieski, D. F., Nathan, B. R., Weingart, S. D., & Smith, W. S. (2012) · Neurocritical Care · doi:10.1007/s12028-012-9751-8 · Cited by 23 · see citing works

Passive Leg Raising: Simple and Reliable Technique to Prevent Fluid Overload in Critically ill Patients

Assadi, F. K. (2017) · International Journal of Preventive Medicine · doi:10.4103/ijpvm.ijpvm_11_17 · Cited by 18 · see citing works

Fluid management strategies in critically ill patients with ARDS: a narrative review

Ziaka, M., & Exadaktylos, A. K. (2025) · European journal of medical research · doi:10.1186/s40001-025-02661-w · Cited by 20 · see citing works

Meningitis and encephalitis management in the ICU

Robinson, C. P., & Busl, K. M. (2019) · Current Opinion in Critical Care · doi:10.1097/mcc.0000000000000640 · Cited by 14 · see citing works

Resolution of remitting seronegative symmetrical synovitis with pitting edema (RS3PE) during Nivolumab therapy for non-small cell lung cancer: a case report.

Filetti, M., Anselmi, E., Macrini, S., Rizzo, F., Iacono, D., Giusti, R., & Marchetti, P. (2018) · Seminars in Arthritis and Rheumatism · doi:10.1016/j.semarthrit.2017.12.013 · Cited by 12 · see citing works

Effect of Fluid Resuscitation Strategies for Obese Patients with Sepsis and Septic Shock: A Systematic Review

Zhang, Y., Wang, M., Lu, Z., & Yang, M. (2022) · Intensive Care Research · doi:10.1007/s44231-022-00019-y · Cited by 9 · see citing works

Improved survival in critically ill patients: are large RCTs more useful than personalized medicine? We are not sure

Gattinoni, L., Tonetti, T., & Quintel, M. (2016) · Intensive Care Medicine · doi:10.1007/s00134-016-4471-8 · Cited by 8 · see citing works

Is venous blood drawn from femoral access adequate to estimate the central venous oxygen saturation and arterial lactate levels in critically ill patients?

Marti, Y. N., Freitas, F. G. R., de Azevedo, R. P., Leão, M., Bafi, A. T., & Machado, F. R. (2015) · Revista Brasileira de Terapia Intensiva · doi:10.5935/0103-507x.20150058 · Cited by 7 · see citing works

The West African Ebola outbreak: finishing the job, preparing for future

Parsons, C., & Ahmad, U. N. (2015) · Transactions of the Royal Society of Tropical Medicine and Hygiene · doi:10.1093/trstmh/trv053 · Cited by 7 · see citing works

"Early goal-directed therapy" versus "Early" and "goal-directed" therapy for severe sepsis and septic shock: Time to rationalize

Dhooria, S., & Agarwal, R. (2015) · Lung India · doi:10.4103/0970-2113.164180 · Cited by 7 · see citing works

Temporal changes in the epidemiology of sepsis‐related intensive care admissions from the emergency department in Australia and New Zealand

Jones, D. A., Moran, J. L., Udy, A. A., Pilcher, D. V., Delaney, A. P., Peake, S., & the ARISE‐TRIPS study investigators (2022) · Emergency Medicine Australasia · doi:10.1111/1742-6723.14034 · Cited by 6 · see citing works

Evidence-based medicine: A predictably flawed paradigm

Keane, M. J., & Berg, C. (2016) · Trends in Anaesthesia and Critical Care · doi:10.1016/j.tacc.2016.07.002 · Cited by 6 · see citing works

Zielorientierte Volumen- und Kreislauftherapie

Haas, S., Saugel, B., Trepte, C. J. C., & Reuter, D. A. (2015) · Der Anaesthesist · doi:10.1007/s00101-015-0035-5 · Cited by 5 · see citing works

Sepsis and Septic Shock: Evolving Evidence, Evolving Paradigms

Shorr, A. F., & Zilberberg, M. D. (2022) · Seminars in Respiratory and Critical Care Medicine · doi:10.1055/s-0041-1740975 · Cited by 4 · see citing works

Nanozymes for Antimicrobes: Precision Biocide

Xu, Z., Li, D., Qiu, Z., & Gao, L. (2020) · Nanostructure science and technology · doi:10.1007/978-981-15-1490-6_15 · Cited by 4 · see citing works

Possibilities of transesophageal echocardiography for assessing the volemic status of patients during direct myocardial revascularization operations on the beating heart: a review

Batigyan, O. A., Lebedeva, Y. A., & Мартынов, Д. В. (2022) · Annals of critical care · doi:10.21320/1818-474x-2021-4-88-97 · Cited by 3 · see citing works

Evidence or belief-based medicine? Ten doubts

Gattinoni, L., Marini, J. J., & Quintel, M. (2017) · Intensive Care Medicine · doi:10.1007/s00134-017-4724-1 · Cited by 3 · see citing works

Analyzing outcomes for peripheral versus central administration of vasopressors: A narrative review

Dryden, J., & Navas‐Blanco, J. R. (2025) · Saudi Journal of Anaesthesia · doi:10.4103/sja.sja_211_25 · Cited by 3 · see citing works

Enhancing intensive care outcome prediction with nutrition information available at admission: An analytic observational study conducted in 31 intensive care units throughout Australia and New Zealand

Simpson, F. O. (2015) · The Sydney eScholarship Repository (The University of Sydney)

Die richtige Hämoglobinkonzentration beim kritisch kranken Patienten

Bone, H.-G. (2015) · Intensivmedizin up2date · doi:10.1055/s-0041-106800

Ebola, Selective Memory and Educational Costs

Brett‐Major, D. M. (2018) · The Journal of the Royal College of Physicians of Edinburgh · doi:10.4997/jrcpe.2018.316

Rise and fall of CVP

Chamala, V. (2022) · Indian Journal of Respiratory Care · doi:10.5005/jp-journals-11010-06102

Sepsis as Organ and Health System Failure

Dickmann, P., & Bauer, M. W. (2020) · Annual update in intensive care and emergency medicine · doi:10.1007/978-3-030-37323-8_47

The Physiology, Pathophysiology, and Clinical Implications of Fluid Resuscitation in Critically Ill Patients

Eraky, A. M., Mokhtar, Y., Khan, A. A., Farag, A., Elawany, S., Alsabbagh, W., Wright, A., & Alamrosy, M. (2026) · Cureus · doi:10.7759/cureus.104736

Early, Goal-Directed Resuscitation for Septic Shock.

Auinger, K., & Maggiorini, M. (2015) · PubMed · doi:10.1056/nejmc1506514 · Cited by 8 · see citing works

Early, Goal-Directed Resuscitation for Septic Shock. The authors reply

(7638896), P. R. M., (7638899), G. S. P., & (7609565), T. J. C. (2015) · Figshare

Goal-Directed Resuscitation for Patients with Early Septic Shock

(13477150), S. L. P., (20681), A. D., (62872), M. B., (982), R. B., (13514155), P. A. C., (13583407), D. J. C., (12059119), A. M. H., (13477117), A. H., (13477165), B. D. H., (15804716), S. A. W., et al. (2024) · Figshare · Cited by 74 · see citing works

Goal-directed resuscitation in sepsis: The game continues but the goalposts have been removed.

Al-Soufi, S., & Nayyar, V. (2015) · PubMed

Goal-Directed Resuscitation for Patients with Early Septic Shock The ARISE Investigators and the ANZICS Clinical Trials Group*

Peake, S., Bailey, M., Bellomo, R., Cooper, D. J., Higgins, A. M., & Howe, B. D. (2014) · Cited by 142 · see citing works