Racial Differences in Genomic Profiling of Prostate Cancer

Clinical use of current polygenic risk scores may exacerbate health disparities

Martin, A. R., Kanai, M., Kamatani, Y., Okada, Y., Neale, B. M., & Daly, M. J. (2019) · Nature Genetics · doi:10.1038/s41588-019-0379-x · Cited by 2,821

AACR Project GENIE: Powering Precision Medicine through an International Consortium

The AACR Project GENIE Consortium, The AACR Project GENIE Consortium, André, F., Arnedos, M., Baras, A. S., Baselga, J., Bedard, P. L., Berger, M. F., Bierkens, M., Calvo, F., et al. (2017) · Cancer Discovery · doi:10.1158/2159-8290.cd-17-0151 · Cited by 1,964

Association of Black Race With Prostate Cancer–Specific and Other-Cause Mortality

Dess, R. T., Hartman, H. E., Mahal, B. A. V., Soni, P., Jackson, W., Cooperberg, M. R., Amling, C. L., Aronson, W. J., Kane, C. J., Terris, M. K., et al. (2019) · JAMA Oncology · doi:10.1001/jamaoncol.2019.0826 · Cited by 416

Disparities in Castration-Resistant Prostate Cancer Trials

Spratt, D. E., & Osborne, J. R. (2015) · Journal of Clinical Oncology · doi:10.1200/jco.2014.58.1751 · Cited by 57

Prostate Cancer Genomic-risk Differences Between African-American and White Men Across Gleason Scores

Mahal, B. A. V., Alshalalfa, M., Spratt, D. E., Davicioni, E., Zhao, S. G., Feng, F. Y.-C., Rebbeck, T. R., Nguyen, P. L., & Huang, F. W. (2019) · European Urology · doi:10.1016/j.eururo.2019.01.010 · Cited by 53

Prevalence of mutations in common tumour types in Northern England and comparable utility of national and international Trial Finders

Rae, S., Plummer, E. R., Fitzgerald, L., Hogarth, L., Bridgewood, A., Brown-Schofield, L.-J., Graham, J., Haigh, S., McAnulty, C., Drew, Y., et al. (2023) · Journal of Cancer Research and Clinical Oncology · doi:10.1007/s00432-023-05365-y · Cited by 2

Navigating Pathways in Prostate Cancer Survivorship: A Comprehensive Review of Challenges, Interventions, and Long-Term Outcomes

Galvez, A., Puri, D., Tran, E., Zaila, K. E., & Santiago‐Lastra, Y. (2025) · Uro · doi:10.3390/uro5020010 · Cited by 2

Subclonal CHD1 deletion is more frequent in African American prostate cancers and associated with rapid disease progression and limited levels of homologous recombination deficiencyPreprint

Dióssy, M., Tisza, V., Li, H., Zhou, J., Sztupinszki, Z. M., Young, D., Nousome, D., Kuo, H., Jiang, J., Chen, Y., et al. (2021) · medRxiv · doi:10.1101/2021.02.08.21251199 · Cited by 2

HIV and SARS-CoV-2 infection in postpartum Kenyan women and their infantsPreprint

Begnel, E. R., Chohan, B. H., Ojee, E., Adhiambo, J., Owiti, P., Ogweno, V. W., Holland, L. A., Fish, C. S., Richardson, B. A., Khan, A. K., et al. (2022) · medRxiv · doi:10.1101/2022.06.23.22276827 · Cited by 2

Prevalence of targetable genomic alterations among a diverse population participating in the ASCO TAPUR Study

Mangat, P. K., Kirkwood, M. K., Hinshaw, D. C., Garrett-Mayer, E. S., & Schilsky, R. L. (2025) · npj Precision Oncology · doi:10.1038/s41698-025-00962-1 · Cited by 1

Under-Representation of Black and Hispanic Men in Metastatic Castration-Resistant Prostate Cancer Trials (2005-2021): A Call to Action

Dirican, C. D., Patel, S. Y., Mardini, A., Sofia, A., Fernandes, B. A. C., Gondhi, V., & Maroules, M. (2025) · JCO Oncology Practice · doi:10.1200/op-25-00827 · Cited by 1

Integrative molecular analyses of lineage identity and morphology in aggressive variant prostate cancer

Li, C., Yin, J., Abel, M. L., Solivan, D. S. V., Bhadresha, K. P., Kartal, S., Nichols, S., Parmar, K., Twohig, J. D., Truong, T. M., et al. (2026) · npj Precision Oncology · doi:10.1038/s41698-026-01400-6 · Cited by 1

The Paradigm of Immune Dysregulation in COVID-19 InfectionPreprint

Sahoo, O. S., Pethusamy, K., Nayek, A., Minocha, R., Dhar, R., & Karmakar, S. (2023) · Preprints.org · doi:10.20944/preprints202307.1880.v1 · Cited by 1

Reply to: Addressing racial and ethnic disparities in AACR project GENIE

Cheung, A. T. M., Niemierko, A., Allen, E. M. V., Vapiwala, N., & Kamran, S. C. (2023) · npj Precision Oncology · doi:10.1038/s41698-023-00426-4 · Cited by 1

Molecular decoupling of lineage identity and morphology in aggressive variant prostate cancerPreprint

Li, C., Yin, J., Abel, M. L., Solivan, D. S. V., Bhadresha, K. P., Kartal, S., Nichols, S., Parmar, K., Twohig, J. D., Truong, T. M., et al. (2026) · medRxiv · doi:10.64898/2026.01.07.26343520 · Cited by 1

Long-Term Complications of Open and Robot-Assisted Laparoscopic Radical Prostatectomy in an Afro-Caribbean Population

Khosla, L., Bamberger, J. N., Uddin, N., Vizgan, G., Fink, L. E., & Winer, A. (2022) · Cureus · doi:10.7759/cureus.25370

Neoplasms of the Prostate

Aparicio, A. M., Pilie, P. G., Surasi, D. S., Choi, S., Chapin, B. F., Logothetis, C. J., & Corn, P. G. (2022) · Wiley eBooks · doi:10.1002/9781119000822.hfcm099.pub2

Precision medicine targets for prostate cancers in African American menPreprint

Jung, M. (2024) · Research Square · doi:10.21203/rs.3.rs-4125012/v1

Oncogenic Alterations, Race, and Survival in US Veterans with Metastatic Prostate Cancer Undergoing Somatic Tumor Next Generation SequencingPreprint

Valle, L., Li, J., Desai, H., Hausler, R. M., Haroldsen, C. L., Chatwal, M. S., Ojo, M., Kelley, M. J., Rebbeck, T. R., Rose, B. S., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.10.24.620071

Real world prevalence of pelvic lymph node involvement in prostate cancer in Asia: do we need a rethink on normograms?

Lau, R., Lee, H. J., Fong, K. Y., Lee, A. Y. M., Tan, Y. G., Law, Y. M., Ngo, N. T., Tuan, J. K. L., Tay, K. J., Lee, L. S., et al. (2025) · Frontiers in Oncology · doi:10.3389/fonc.2025.1583806

Racial disparities in the receipt of therapies for cancer, hypertension, and diabetes, and in mortality in a large population-based cohort of older men with prostate cancer

Li, Z., & Du, X. L. (2025) · Ethnicity and Health · doi:10.1080/13557858.2025.2525791

Inference of Genetic Ancestry from Cancer-Derived Molecular Data with RAIDS

Belleau, P., Deschênes, A., Tuveson, D. A., & Krasnitz, A. (2025) · Methods in molecular biology · doi:10.1007/978-1-0716-4566-6_8

Circulating cell-free DNA profiling reveals ancestry-dependent genetic variation in metastatic prostate cancer

Maleknia, S., Hassoun, R., Adra, N., & Shahbazi, R. (2026) · Molecular Biomedicine · doi:10.1186/s43556-026-00405-8

The distinct molecular profile of metastatic prostate cancer in the mixed Brazilian population

Macedo, G. S., Schuch, J. B., Cadore, N. A., de Baumont, A. C., Curzel, G. D., Bordignon, C., Lopes, R. M., Rosa, B., Louzeiro, D. L. C., do, R. B. L. A., et al. (2026) · Genetics in Medicine Open · doi:10.1016/j.gimo.2026.104403

Platelet–Prostate cancer crosstalk driving disparities and therapeutic vulnerabilities

Mariani, V., & Lee, N. H. (2026) · Discover Oncology · doi:10.1007/s12672-026-05369-3

Diagnostic performance of 18F-prostate-specific membrane antigen-1007 PET/computed tomography and multiparametric MRI in prostate cancer: application of the PRIMARY score in a sub-Saharan African cohort

Loyal, P. K., Olwit, W. K., Shah, J., Mwania, M. M., Makhdomi, K. B., & Gitau, S. N. (2026) · Nuclear Medicine Communications · doi:10.1097/mnm.0000000000002202

Homologous Recombination and Mismatch Repair Assessment in Men With Advanced Prostate Cancer: A Cross-Sectional Study From a Center in Mexico City

Rodríguez-Olivares, J. L., Pineda, M. M., Beas-Lozano, E. L., Seidman-Sorsby, A., Remolina-Bonilla, Y. A., Gamboa‐Domínguez, A., Weitzel, J. N., Barata, P., Chavarri-Guerra, Y., & Bourlon, M. T. (2026) · ONCOLOGY · doi:10.46883/2026.25921234

Subclonal Complete Loss of CDKN1B as a Common Genomic Alteration in Prostate Cancer: Associations With Race and Prostate Cancer Outcomes

Sfanos, K. S., Morton, R., Flores, J., Sosa, R. Y., Ernst, S. E., Mummert, L. A., Hicks, J., Lotan, T. L., Lu, J., Jing, Y., et al. (2026) · Modern Pathology · doi:10.1016/j.modpat.2026.101065

Molecular stratification of SPOP-mutant prostate cancer demonstrates Wnt signaling and replication stress signatures in diverse patient populations

Rizwan, K., Manikonda, S. P. R., Dowst, H., Castro, P., Echartea, M. E. R., Coarfa, C., Ittmann, M., Zarrin‐Khameh, N., Huang, Q., Mims, M. P., et al. (2026) · Cell Reports · doi:10.1016/j.celrep.2026.118006

Personalized genomic landscape of prostate cancer in African American men reveals novel drivers and therapeutic opportunities

Murthy, S., Fago, K., Knight, J., Kowalczyk, K. J., Hankins, R. A., Bandi, G., Dritschilo, A., & Jung, M. (2026) · PLoS ONE · doi:10.1371/journal.pone.0360389

Epidemiology, Risk Factors, and Prevention of Prostate Cancer

Gandaglia, G., Weiner, A. B., Briganti, A., Eeles, R. A., Eggener, S. E., Gleave, M., Graefen, M., Vecchia, C. L., Mignozzi, S., Stattin, P. E., et al. (2026) · European Urology · doi:10.1016/j.eururo.2026.10.007

Molecular Discriminators of Racial Disparities in Prostate Cancer

Ateeq, B., Bhatia, V., & Goel, S. (2016) · Trends in cancer · doi:10.1016/j.trecan.2016.01.005 · Cited by 11

Genetic ancestry associations with somatic mutations in a real-world cohort of over 3,000 patients with prostate cancer.

Vega, F. M. D. L., Rhead, B. L., Pouliot, Y., Guinney, J., Craig, D. W., & Carpten, J. D. (2023) · Journal of Clinical Oncology · doi:10.1200/jco.2023.41.16_suppl.5034

Race and prostate cancer: genomic landscape

Gallo, C. A., Owiredu, J. N., Weinstein, I., Lewicki, P., Basourakos, S. P., Vince, R., Awamlh, B. A. H. A., Schumacher, F. R., Spratt, D. E., Barbieri, C. E., et al. (2022) · Nature Reviews Urology · doi:10.1038/s41585-022-00622-0 · Cited by 36

Abstract C045: Investigating molecular and genetic contributions to racial disparities in prostate cancer by integrating multi-omic datasets available in public

Hightower, A. J., Rhie, S. K., Falzarano, S. M., & Buxbaum, S. G. (2023) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1538-7755.disp22-c045

Gene Alterations Linked to Prostate Cancer Disparities

Froelich, W. (2020) · Oncology Times · doi:10.1097/01.cot.0000725488.32051.39