The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Coagulopathy and Antiphospholipid Antibodies in Patients with Covid-19
Open accessAbstract
The authors describe a 69-year-old man with Covid-19 diagnosed in January 2020 in Wuhan, China, along with two other critically ill patients with Covid-19 who were also seen in the same intensive care unit. Coagulopathy and antiphospholipid antibodies were seen in all three patients.
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“Multiple immunostaining studies reveal that ACE2 protein in the human brain is predominantly or exclusively expressed in vasculature (and specifically expressed within pericytes) (52, 53, 70), and many neurological symptoms associated with CoV-2 infection like stroke or altered consciousness are consistent with an underlying vasculopathy (71-76).”
From Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia (2020) · cites this paper as [71]
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Cites
Viral infections and antiphospholipid antibodies
Uthman, I. W., & Gharavi, A. E. (2002) · Seminars in Arthritis and Rheumatism · doi:10.1053/sarh.2002.28303 · Cited by 302
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Bikdeli, B., Madhavan, M. V., Jiménez, D., Chuich, T., Dreyfus, I., Driggin, E., Der-Nigoghossian, C. A., Ageno, W., Madjid, M., Guo, Y., et al. (2020) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2020.04.031 · Cited by 2,967
Pathological inflammation in patients with COVID-19: a key role for monocytes and macrophages
Merad, M., & Martin, J. C. (2020) · Nature Reviews Immunology · doi:10.1038/s41577-020-0331-4 · Cited by 2,472
Neurological associations of COVID-19
Ellul, M. A., Benjamin, L., Singh, B., Lant, S., Michael, B. D., Easton, A., Kneen, R., Defres, S., Sejvar, J., & Solomon, T. (2020) · The Lancet Neurology · doi:10.1016/s1474-4422(20)30221-0 · Cited by 2,156
Neutrophil extracellular traps in COVID-19
Zuo, Y., Yalavarthi, S., Shi, H., Gockman, K., Zuo, M., Madison, J. A., Blair, C., Weber, A. G., Barnes, B. J., Egeblad, M., et al. (2020) · JCI Insight · doi:10.1172/jci.insight.138999 · Cited by 1,598
Varatharaj, A., Thomas, N., Ellul, M. A., Davies, N. W. S., Pollak, T. A., Tenorio, E. L., Sultan, M., Easton, A., Breen, G., Zandi, M., et al. (2020) · The Lancet Psychiatry · doi:10.1016/s2215-0366(20)30287-x · Cited by 1,246
Metadata
- Authors
- Zhang, Y., Xiao, M., Zhang, S., Xia, P., Cao, W., Jiang, W., Chen, H., Ding, X., Zhao, H., Zhang, H., Wang, C., Zhao, J., Sun, X., Tian, R., Wu, W., Wu, D., Ma, J., Chen, Y., Zhang, D., Xie, J., Yan, X., Zhou, X., Liu, Z., Wang, J., Du, B., Qin, Y., Gao, P., Qin, X., Xu, Y., Zhang, W., Li, T., Zhang, F., Zhao, Y., Li, Y., & Zhang, S.
- Affiliations
- Peking Union Medical College Hospital (CN)
- Peking Union Medical College Hospital, Beijing, China
- ORCID
- Zhang, Yan
- Xiao, Meng
- Zhang, Shulan
- Cao, Wei
- Jiang, Wei
- Chen, Huan
- Ding, Xin
- Zhao, Hua
- Zhang, Hongmin
- Wang, Chunyao
- Zhao, Jing
- Wu, Wei
- Wu, Dong
- Ma, Jie
- Zhang, Dong
- Xie, Jing
- Yan, Xiaowei
- Zhou, Xiang
- Du, Bin
- Qin, Yan
- Gao, Peng
- Qin, Xuzhen
- Xu, Yingchun
- Zhang, Wen
- Li, Taisheng
- Zhang, Fengchun
- Zhao, Yongqiang
- Li, Yongzhe
- Zhang, Shuyang
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2020-04-23
- Volume
- 382
- Issue
- 17
- Pages
- e38-e38
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- PMC
- PMC7161262
- OpenAlex
- W3014573995
- Cited by
- 2,179
- References
- 1
- Citations by year
- 2026: 17 · 2025: 37 · 2024: 88 · 2023: 143 · 2022: 280 · 2021: 630 · 2020: 973
- FWCI
- 66.46
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Infectious Diseases › COVID-19 Clinical Research Studies
- Health Sciences › Medicine › Rheumatology › Systemic Lupus Erythematosus Research
- Health Sciences › Medicine › Hematology › Heparin-Induced Thrombocytopenia and Thrombosis
- Keywords
- COVID-19 pandemic, coagulopathy, antiphospholipid antibodies, critically ill patients, intensive care unit, thrombosis, hypercoagulability
- MeSH terms
- COVID-19, Aged, Antibodies, Anti-Idiotypic, Blood Coagulation Disorders, Humans, Immunoglobulin A, Immunoglobulin G, Male, Pneumonia, Viral, Antibodies, Antiphospholipid, Antibodies, Anticardiolipin, Coronavirus Infections, Pandemics
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