Collateral Effect of Covid-19 on Stroke Evaluation in the United States
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Use of Stroke Imaging during the Covid-19 Pandemic The authors reviewed an imaging database used to determine whether patients with acute stroke were eligible to undergo endovascular thrombectomy. ...
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Previous studies have reported significant reductions in hospital admissions for myocardial infarction and stroke during the COVID-19 pandemic.
“Previous studies have also reported significant reductions in hospital admissions for MI and stroke during the COVID-19 pandemic (2–7).”
From Potential Indirect Effects of the COVID-19 Pandemic on Use of Emergency Departments for Acute Life-Threatening Conditions — United States, January–May 2020 (2020) · cites this paper as [7]
The paper reports a 39% decrease in patients undergoing acute-stroke imaging at U.S. hospitals during the early pandemic. It explicitly describes imaging as a surrogate for care provided, not a count of stroke admissions, and does not report myocardial-infarction admissions. (LLM, conf=0.88)
Experimental — accuracy not yet measuredNeuroimaging data from approximately 850 U.S. hospitals indicate a 39% reduction in the number of patients who were evaluated for signs of stroke.
“and neuroimaging data from approximately 850 U.S. hospitals indicate a 39% reduction in the number of patients who were evaluated for signs of stroke (7).”
Public health interventions, limited medical care, and behavioral changes could have contributed to the surge in excess deaths unrelated to COVID-19 in young adults, resulting in a notable peak of mortality in summer 2020.
“Public health interventions, limited medical care, and behavioral changes (e.g., delays in seeking timely medical help due to fear of infection) (Bollmann et al., 2020; Kansagra et al., 2020; Mafham et al., 2020; Woolf et al., 2021) could have contributed to the surge in excess deaths unrelated to COVID-19 in young adults, resulting in a notable peak of mortality in summer 2020.”
From Direct and indirect mortality impacts of the COVID-19 pandemic in the United States, March 1, 2020 to January 1, 2022 (2023) · cites this paper as Kansagra et al., 2020
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Goyal, M., Menon, B. K., van Zwam, W. H., Dippel, D. W. J., Mitchell, P. J., Demchuk, A. M., Dávalos, A., Majoie, C. B. L. M., van der Lugt, A., de Miquel, M. Á., et al. (2016) · The Lancet · doi:10.1016/s0140-6736(16)00163-x · Cited by 7,866 · see citing works
Self-citationThrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct
Nogueira, R. G., Jadhav, A. P., Haussen, D. C., Bonafé, A., Budzik, R. F., Bhuva, P., Yavagal, D. R., Ribó, M., Cognard, C., Hanel, R. A., et al. (2017) · New England Journal of Medicine · doi:10.1056/nejmoa1706442 · Cited by 5,667 · see citing works
Thrombectomy for Stroke at 6 to 16 Hours with Selection by Perfusion Imaging
Albers, G. W., Marks, M. P., Kemp, S. M., Christensen, S., Tsai, J. P.-C., Ortega‐Gutiérrez, S., McTaggart, R., Torbey, M., Kim‐Tenser, M. A., Leslie‐Mazwi, T. M., et al. (2018) · New England Journal of Medicine · doi:10.1056/nejmoa1713973 · Cited by 4,966 · see citing works
Self-citationGarcia, S., Albaghdadi, M. S., Meraj, P. M., Schmidt, C., Garberich, R., Jaffer, F. A., Dixon, S., Rade, J. J., Tannenbaum, M., Chambers, J., et al. (2020) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2020.04.011 · Cited by 1,194 · see citing works
Perfusion Computed Tomography in Acute Ischemic Stroke
Heit, J. J., Sussman, E. S., & Wintermark, M. (2019) · Radiologic Clinics of North America · doi:10.1016/j.rcl.2019.06.003 · Cited by 15 · see citing works
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Kontis, V., Bennett, J. E., Rashid, T., Parks, R. M., Pearson-Stuttard, J., Guillot, M., Asaria, P., Zhou, B., Battaglini, M., Corsetti, G., et al. (2020) · Nature Medicine · doi:10.1038/s41591-020-1112-0 · Cited by 410 · see citing works
Lange, S. J., Ritchey, M. D., Goodman, A. B., Dias, T., Twentyman, E., Fuld, J., Schieve, L. A., Imperatore, G., Benoit, S. R., Kite-Powell, A., et al. (2020) · MMWR Morbidity and Mortality Weekly Report · doi:10.15585/mmwr.mm6925e2 · Cited by 367 · see citing works
Excess mortality: the gold standard in measuring the impact of COVID-19 worldwide?
Beaney, T., Clarke, J. M., Jain, V., Golestaneh, A. K., Lyons, G., Salman, D., & Majeed, A. (2020) · Journal of the Royal Society of Medicine · doi:10.1177/0141076820956802 · Cited by 370 · see citing works
Thrombotic complications of COVID-19
Avila, J., Long, B., Holladay, D., & Gottlieb, M. (2021) · The American Journal of Emergency Medicine · doi:10.1016/j.ajem.2020.09.065 · Cited by 143 · see citing works
Lee, W.-E., Woo Park, S., Weinberger, D. M., Olson, D., Simonsen, L., Grenfell, B. T., & Viboud, C. (2023) · eLife · doi:10.7554/elife.77562 · Cited by 90 · see citing works
Excess cerebrovascular mortality in the united states during the COVID-19 pandemic
Sharma, R., Kuohn, L. R., Weinberger, D. M., Warren, J. L., Sansing, L. H., Jasne, A., Falcone, G., Dhand, A., & Sheth, K. N. (2021) · Stroke · doi:10.1161/strokeaha.120.031975 · Cited by 46 · see citing works
Odone, A., Delmonte, D., Gaetti, G., & Signorelli, C. (2021) · Public Health · doi:10.1016/j.puhe.2020.11.016 · Cited by 34 · see citing works
- Authors
- Kansagra, A. P., Goyal, M. S., Hamilton, S., & Albers, G. W.
- Affiliations
- Washington University in St. Louis (US)
- Stanford University (US)
- Corresponding author
- Kansagra, Akash P.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2020-07-23
- Volume
- 383
- Issue
- 4
- Pages
- 400-401
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- PMC
- PMC7233187
- OpenAlex
- W3020954032
- Cited by
- 432
- References
- 5
- Citations by year
- 2026: 9 · 2025: 9 · 2024: 18 · 2023: 22 · 2022: 57 · 2021: 145 · 2020: 172
- FWCI
- 35.75
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Oncology › COVID-19 and healthcare impacts
- Health Sciences › Medicine › Epidemiology › Acute Ischemic Stroke Management
- Health Sciences › Medicine › Infectious Diseases › COVID-19 Clinical Research Studies
- Keywords
- COVID-19 pandemic, acute ischemic stroke, mechanical thrombectomy, stroke imaging, stroke assessment
- MeSH terms
- Betacoronavirus, COVID-19, SARS-CoV-2, Humans, Pneumonia, Viral, United States, Databases, Factual, Coronavirus Infections, Stroke, Pandemics, Neuroimaging
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