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Rapid Decay of Anti–SARS-CoV-2 Antibodies in Persons with Mild Covid-19
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Covid-19 Antibodies after Mild Infection Among 34 volunteers who had recovered from mild Covid-19 illness, antiviral antibodies to the receptor-binding domain of the viral spike protein declined wi...
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“However, neutralizing antibody responses decay rapidly in early convalescence9,14–17.”
From Prospects for durable immune control of SARS-CoV-2 and prevention of reinfection (2021) · cites this paper as [14]
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Metadata
- Authors
- Ibarrondo, F. J., Fulcher, J. A., Goodman-Meza, D., Elliott, J., Hofmann, C., Hausner, M. A., Ferbas, K. G., Tobin, N. H., Aldrovandi, G. M., & Yang, O. O.
- Affiliations
- University of California, Los Angeles (US)
- David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, CA
- Corresponding author
- Yang, Otto O.
- ORCID
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2020-09-10
- Volume
- 383
- Issue
- 11
- Pages
- 1085-1087
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- PMC
- PMC7397184
- OpenAlex
- W3044311014
- Cited by
- 1,021
- References
- 5
- Citations by year
- 2026: 12 · 2025: 28 · 2024: 36 · 2023: 92 · 2022: 198 · 2021: 476 · 2020: 177
- FWCI
- 30.93
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- Funders
- McCarthy Family Foundation
- AIDS Healthcare Foundation (Grant to OOY)
- National Institutes of National Institute of Allergy and Infectious Diseases (AI124979, AI131879, AI140775, UM1AI068616, UM1AI068632, UM1AI106716)
- Doris Duke Charitable Foundation (2019086)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development
- National Institute of Mental Health
- James B. Pendleton Charitable Trust
- Topics
- Health Sciences › Medicine › Infectious Diseases › SARS-CoV-2 and COVID-19 Research
- Health Sciences › Medicine › Infectious Diseases › COVID-19 Clinical Research Studies
- Physical Sciences › Mathematics › Modeling and Simulation › COVID-19 epidemiological studies
- Keywords
- SARS-CoV-2, COVID-19 pandemic, antibody persistence, anti-spike antibodies, receptor binding domain, mild COVID-19, antibody waning
- MeSH terms
- Betacoronavirus, COVID-19, SARS-CoV-2, Adult, Aged, Antibodies, Viral, Female, Humans, Immunoglobulin G, Male, Middle Aged, Pneumonia, Viral, Coronavirus Infections, Young Adult, Pandemics
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