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Rapid Decay of Anti–SARS-CoV-2 Antibodies in Persons with Mild Covid-19
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Covid-19 Antibodies after Mild Infection Among 34 volunteers who had recovered from mild Covid-19 illness, antiviral antibodies to the receptor-binding domain of the viral spike protein declined wi...
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“However, neutralizing antibody responses decay rapidly in early convalescence9,14–17.”
From Prospects for durable immune control of SARS-CoV-2 and prevention of reinfection (2021) · cites this paper as [14]
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Brehm, J., Spaeth, A., Dreßler, L., Masetto, T., Dannenberg, R., Peter, C., & Grimmler, M. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.915338 · Cited by 5
RETRACTED: The pathogenicity of COVID-19 and the role of pentraxin-3: An updated review study
Margiana, R., Sharma, S. K., Khan, B. I., Alameri, A. A., Opulencia, M. J. C., Hammid, A. T., Hamza, T. A., Хамракулович, Б. Ш., Abdelbasset, W. K., & Jawhar, Z. H. (2022) · Pathology - Research and Practice · doi:10.1016/j.prp.2022.154128 · Cited by 5
RetractedKharroubi, G., Cherif, I., Ghawar, W., Dhaouadi, N., Yazidi, R., Châabane, S., Snoussi, M. A., Salem, S., Hamouda, W. B., Hamouda, S. B., et al. (2023) · Archives of Virology · doi:10.1007/s00705-022-05636-y · Cited by 5
Mouna, L., Razazian, M., Duquesne, S., Roque‐Afonso, A., & Vauloup‐Fellous, C. (2023) · Viruses · doi:10.3390/v15020426 · Cited by 6
García‐Carreras, B., Hitchings, M. D. T., Johansson, M. A., Biggerstaff, M., Slayton, R. B., Healy, J. M., Lessler, J., Quandelacy, T. M., Salje, H., Huang, A. T., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-37944-5 · Cited by 5
Dhawan, M. K., Thakur, N., Sharma, M. K., & Rabaan, A. A. (2025) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2025.117936 · Cited by 5
COVID-19-Pandemie-bedingte Belastungen und SARS-CoV-2-Prävalenz in Pflegeeinrichtungen
Perkhofer, L., Grünke, P., Gashi-Ymeri, E., Grünke, T., Kroschel, J., Michel, D., Pensel, E., Rost, A., Denkinger, M. D., Dallmeier, D., et al. (2021) · Zeitschrift für Gerontologie und Geriatrie · doi:10.1007/s00391-021-01931-6 · Cited by 5
The protective immunity induced by SARS-CoV-2 infection and vaccination: a critical appraisal
Tosta, E. (2021) · Exploration of Immunology · doi:10.37349/ei.2021.00014 · Cited by 5
Comparison of SARS-CoV-2 variant lethality in human angiotensin-converting enzyme 2 transgenic mice
Lee, T. Y., Lee, H., Kim, N., Jeon, P., Kim, J., Lim, H., Yang, J., Kim, K.-C., & Lee, J.-Y. (2021) · Virus Research · doi:10.1016/j.virusres.2021.198563 · Cited by 4
Practical management of patients with hematological diseases during the COVID-19 pandemic in Japan
Hagihara, M., Ohara, S., Uchida, T., & Inoue, M. (2021) · International Journal of Hematology · doi:10.1007/s12185-021-03175-x · Cited by 5
de Boer, J., Saade, U., Granjon, E., Trouillet‐Assant, S., Saade, C., Pottel, H., Zrein, M. A., & Covid ser study group (2022) · PLoS ONE · doi:10.1371/journal.pone.0274553 · Cited by 6
Pidal, P., Fernández, J. O., Airola, C., Araujo, M., Menjiba, A. M., Martín, H. S., Bruneau, N., Balanda, M., Elgueta, C., Fasce, R., et al. (2022) · Medical Microbiology and Immunology · doi:10.1007/s00430-022-00753-6 · Cited by 5
Adeniyi, O. V., Durojaiye, O. C., & Masilela, C. M. (2023) · Vaccines · doi:10.3390/vaccines11061068 · Cited by 5
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Provencio, M., Rodríguez‐Abreu, D., Granados, A. L. O., Serrano, G., Aguado, C., Franco, F., Gutiérrez, V., López-Vivanco, G., Guirado, M., Benítez, G., et al. (2021) · Translational Lung Cancer Research · doi:10.21037/tlcr-21-504 · Cited by 5
Antibody Response to SARS-CoV-2 in Relation to the Contributing Factors in COVID-19 Patients
Aziz, H., Fatima, S., Mahmood, H., Muhammad, S., Saeed, M. A. R., Khurshid, S., Aslam, W., Aziz, S., & Faheem, M. (2022) · Viral Immunology · doi:10.1089/vim.2021.0097 · Cited by 5
Chen, L., Pang, P., Qi, H., Yan, K., Ren, Y., Ma, M., Cao, R., Li, H., Hu, C., Li, Y., et al. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.770982 · Cited by 5
Seroprevalence of immunoglobulin G antibodies against SARS-CoV-2 in Cyprus
Papaneophytou, C. P., Nicolaou, A., Pieri, M., Nicolaidou, V., Galatou, E., Sarigiannis, Y. M., Pantelidou, M., Panayi, P., Thoma, T., Stavraki, A., et al. (2022) · PLoS ONE · doi:10.1371/journal.pone.0269885 · Cited by 6
MacLeod, M. R., & Hunter, D. G. (2021) · INFORMS Journal on Applied Analytics · doi:10.1287/inte.2020.1070 · Cited by 5
Vidales, E. P. R., Garza‐Carrillo, D., Perez‐Trujillo, J. J., Robles‐Rodríguez, O. A., Salinas-Martı́nez, A. M., Montes‐de‐Oca‐Luna, R., Treviño‐Garza, C., & de la O-Cavazos, M. E. (2021) · Journal of Medical Virology · doi:10.1002/jmv.27131 · Cited by 5
Letter to the Editor: The Interpretation of COVID-19 Seroprevalence Study Should Be Cautious
Lee, J., Kim, S. Y., Sung, H., Choe, Y. J., & Hong, K. H. (2020) · Journal of Korean Medical Science · doi:10.3346/jkms.2020.35.e338 · Cited by 5
Metadata
- Authors
- Ibarrondo, F. J., Fulcher, J. A., Goodman-Meza, D., Elliott, J., Hofmann, C., Hausner, M. A., Ferbas, K. G., Tobin, N. H., Aldrovandi, G. M., & Yang, O. O.
- Affiliations
- University of California, Los Angeles (US)
- David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, CA
- Corresponding author
- Yang, Otto O.
- ORCID
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2020-09-10
- Volume
- 383
- Issue
- 11
- Pages
- 1085-1087
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- PMC
- PMC7397184
- OpenAlex
- W3044311014
- Cited by
- 1,021
- References
- 5
- Citations by year
- 2026: 12 · 2025: 28 · 2024: 36 · 2023: 92 · 2022: 198 · 2021: 476 · 2020: 177
- FWCI
- 30.93
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- Funders
- McCarthy Family Foundation
- AIDS Healthcare Foundation (Grant to OOY)
- National Institutes of National Institute of Allergy and Infectious Diseases (AI124979, AI131879, AI140775, UM1AI068616, UM1AI068632, UM1AI106716)
- Doris Duke Charitable Foundation (2019086)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development
- National Institute of Mental Health
- James B. Pendleton Charitable Trust
- Topics
- Health Sciences › Medicine › Infectious Diseases › SARS-CoV-2 and COVID-19 Research
- Health Sciences › Medicine › Infectious Diseases › COVID-19 Clinical Research Studies
- Physical Sciences › Mathematics › Modeling and Simulation › COVID-19 epidemiological studies
- Keywords
- SARS-CoV-2, COVID-19 pandemic, antibody persistence, anti-spike antibodies, receptor binding domain, mild COVID-19, antibody waning
- MeSH terms
- Betacoronavirus, COVID-19, SARS-CoV-2, Adult, Aged, Antibodies, Viral, Female, Humans, Immunoglobulin G, Male, Middle Aged, Pneumonia, Viral, Coronavirus Infections, Young Adult, Pandemics
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