Incidence of chronic kidney disease among adults with diabetes, 2015-2020
Open accessAbstract
The prevalence of kidney failure warranting dialysis or transplantation more than doubled between 2000 and 2019 to nearly 800,000 persons in the United States, with diabetes as the leading cause in 47% of those affected.1,2 The incidence of chronic kidney disease (CKD) among patients with diabetes is unknown, yet such data are vital for identifying high-risk populations, determining the effectiveness of interventions, and assessing the effects on health care delivery and public health responses.
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Reduced eGFR without albuminuria has been frequently reported in type 1 and type 2 diabetes and is becoming more common over time as the prevalence of diabetes increases in the U.S.
“Reduced eGFR without albuminuria has been frequently reported in type 1 and type 2 diabetes and is becoming more common over time as the prevalence of diabetes increases in the U.S. (2,3,18,20,21).”
From 11. Chronic Kidney Disease and Risk Management: Standards of Care in Diabetes—2026 (2026) · cites this paper as [3]
In “TO THE EDITOR” (page unavailable), the paper treats reduced eGFR as a CKD criterion independent of albuminuria and notes a large increase in diabetes prevalence. It does not report how frequently reduced eGFR occurs without albuminuria in type 1 or type 2 diabetes, or show that this phenotype is becoming more common. Its measured outcome—overall CKD incidence among adults with diabetes—declined from 2015–2016 to 2019–2020. (LLM, conf=0.83)
Experimental — accuracy not yet measuredThe incidence of CKD in people with diabetes has decreased over the last decade but remains high in the U.S. and around the world.
“The incidence of CKD in people with diabetes has decreased over the last decade but remains high in the U.S. (3) and around the world (7).”
From 11. Chronic Kidney Disease and Risk Management: Standards of Care in Diabetes—2026 (2026) · cites this paper as [3]
CKD attributed to diabetes in adults occurs in 20-40% of people with diabetes.
“In this section, the focus is on CKD attributed to diabetes in adults, which occurs in 20-40% of people with diabetes (1)(2)(3)(4).”
From 11. Chronic Kidney Disease and Risk Management: Standards of Care in Diabetes—2026 (2026) · cites this paper as [3]
The “To the Editor” section reports CKD incidence among adults with diabetes in two U.S. health care systems, not the proportion of people with diabetes who have CKD. Searches for the 20–40% figure and CKD prevalence found no passage in our copy supporting that estimate; no page number is available. (LLM, conf=0.76)
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- Authors
- Tuttle, K. R., Jones, C. R., Daratha, K. B., Koyama, A. K., Nicholas, S. B., Alicic, R. Z., Duru, O. K., Neumiller, J. J., Norris, K. C., Ríos Burrows, N., & Pavkov, M. E.
- Affiliations
- Providence Health, Spokane, WA
- Centers for Disease Control and Prevention (US)
- University of California, Los Angeles (US)
- Centers for Disease Control and Prevention, Atlanta, GA
- ORCID
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2022-10-13
- Volume
- 387
- Issue
- 15
- Pages
- 1430-1431
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- PMC
- PMC10701747
- OpenAlex
- W4304809004
- Cited by
- 109
- References
- 4
- Citations by year
- 2026: 18 · 2025: 33 · 2024: 34 · 2023: 22 · 2022: 2
- FWCI
- 14.44
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- Centers for Disease Control and Prevention (75D301-21-P-12254)
- Topics
- Health Sciences › Medicine › Nephrology › Chronic Kidney Disease and Diabetes
- Health Sciences › Medicine › Nephrology › Dialysis and Renal Disease Management
- Health Sciences › Medicine › Nephrology › Acute Kidney Injury Research
- Keywords
- chronic kidney disease, diabetes mellitus, incidence, renal failure, dialysis, kidney transplantation, adults
- MeSH terms
- Adult, Diabetes Mellitus, Type 2, Diabetic Nephropathies, Glomerular Filtration Rate, Humans, Kidney Failure, Chronic, Risk Factors, Incidence, Renal Insufficiency, Chronic
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
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